NVP-AUY922 alleviates radiation-induced lung injury via inhibition of autophagy-dependent ferroptosis

Chaperone-mediated autophagy sustains haematopoietic stem-cell function

(2021) Shuxian Dong et al.   NATURE

Ferroptosis, radiotherapy, and combination therapeutic strategies

(2021) Guang Lei et al.   Protein & Cell

Inhibition of TLR4 prevents hippocampal hypoxic-ischemic injury by regulating ferroptosis in neonatal rats

(2021) Kaiyi Zhu et al.   EXPERIMENTAL NEUROLOGY

Radiation-Induced Lipid Peroxidation Triggers Ferroptosis and Synergizes with Ferroptosis Inducers

(2020) Ling F. Ye et al.   ACS Chemical Biology

Natural heat shock protein 90 inhibitors in cancer and inflammation

(2020) Thadeu E.M.M. Costa et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Ferroptosis at the crossroads of infection, aging and cancer

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Post-treatment with a heat shock protein 90 inhibitor prevents chronic lung injury and pulmonary fibrosis, following acute exposure of mice to HCl

(2020) Margarita Marinova et al.   EXPERIMENTAL LUNG RESEARCH

The emerging role of ferroptosis in inflammation

(2020) Yitian Sun et al.   BIOMEDICINE & PHARMACOTHERAPY

Inhibition of the NLRP3 inflammasome by HSP90 inhibitors

(2020) Sohaib Nizami et al.   IMMUNOLOGY

Ferroptosis in plants: triggers, proposed mechanisms and the role of iron in modulating cell death

(2020) Ayelén Mariana Distéfano et al.   JOURNAL OF EXPERIMENTAL BOTANY

Crosstalk Between Autophagy and Ferroptosis and Its Putative Role in Ischemic Stroke

(2020) Jie Liu et al.   Frontiers in Cellular Neuroscience

Mechanisms of Ferroptosis and Relations With Regulated Cell Death: A Review

(2019) Pengxu Lei et al.   Frontiers in Physiology

Chaperone-mediated autophagy is involved in the execution of ferroptosis

(2019) Zheming Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Radiation-Induced Lung Injury

(2019) Alexander N. Hanania et al.   CHEST

Modern radiotherapy in cancer treatment during pregnancy

(2019) Rosario Mazzola et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Ferroptosis inhibitor alleviates Radiation-induced lung fibrosis (RILF) via down-regulation of TGF-β1

(2019) Xuan Li et al.   Journal of Inflammation-London

Radiation-Induced Lung Injury (RILI)

(2019) Lorena Giuranno et al.   Frontiers in Oncology

Recent Progress in Ferroptosis Inducers for Cancer Therapy

(2019) Chen Liang et al.   ADVANCED MATERIALS

Role of ferroptosis in the process of acute radiation-induced lung injury in mice

(2019) Xuan Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Bayesian Adaptive Randomization Trial of Passive Scattering Proton Therapy and Intensity-Modulated Photon Radiotherapy for Locally Advanced Non–Small-Cell Lung Cancer

(2018) Zhongxing Liao et al.   JOURNAL OF CLINICAL ONCOLOGY

Phase 2 Study of the HSP-90 Inhibitor AUY922 in Previously Treated and Molecularly Defined Patients with Advanced Non–Small Cell Lung Cancer

(2018) Enriqueta Felip et al.   Journal of Thoracic Oncology

Mesenchymal stem cell-based therapy for radiation-induced lung injury

(2018) Tiankai Xu et al.   Stem Cell Research & Therapy

Ferroptosis Contributes to Neuronal Death and Functional Outcome After Traumatic Brain Injury

(2018) Elizabeth M. Kenny et al.   CRITICAL CARE MEDICINE

Nrf2 inhibition reverses resistance to GPX4 inhibitor-induced ferroptosis in head and neck cancer

(2018) Daiha Shin et al.   FREE RADICAL BIOLOGY AND MEDICINE

Heat shock protein antagonists in early stage clinical trials for NSCLC

(2017) Lizza E.L. Hendriks et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Neuronal Death After Hemorrhagic Stroke In Vitro and In Vivo Shares Features of Ferroptosis and Necroptosis

(2017) Marietta Zille et al.   STROKE

Ferroptosis: Death by Lipid Peroxidation

(2016) Wan Seok Yang et al.   TRENDS IN CELL BIOLOGY

Intravenous delivery of adipose-derived mesenchymal stromal cells attenuates acute radiation-induced lung injury in rats

(2015) Xinping Jiang et al.   CYTOTHERAPY

Standard-dose versus high-dose conformal radiotherapy with concurrent and consolidation carboplatin plus paclitaxel with or without cetuximab for patients with stage IIIA or IIIB non-small-cell lung cancer (RTOG 0617): a randomised, two-by-two factorial phase 3 study

(2015) Jeffrey D Bradley et al.   LANCET ONCOLOGY

HSP90 Inhibition Suppresses Lipopolysaccharide-Induced Lung Inflammation In Vivo

(2015) Andrew Lilja et al.   PLoS One

Entering the lysosome through a transient gate by chaperone-mediated autophagy

(2014) Urmi Bandyopadhyay et al.   Autophagy

Regulation of Ferroptotic Cancer Cell Death by GPX4

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LAMP2A overexpression in breast tumors promotes cancer cell survival via chaperone-mediated autophagy

(2012) Tapas Saha   Autophagy

Melatonin reduces X-ray radiation-induced lung injury in mice by modulating oxidative stress and cytokine expression

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Cyclodepsipeptide toxin promotes the degradation of Hsp90 client proteins through chaperone-mediated autophagy

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Targeting Hsp90: small-molecule inhibitors and their clinical development

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