Glycation modulates glutamatergic signaling and exacerbates Parkinson’s disease-like phenotypes
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Title
Glycation modulates glutamatergic signaling and exacerbates Parkinson’s disease-like phenotypes
Authors
Keywords
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Journal
npj Parkinsons Disease
Volume 8, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2022-04-25
DOI
10.1038/s41531-022-00314-x
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Note: Only part of the references are listed.- α-Synuclein Oligomers Induce Glutamate Release from Astrocytes and Excessive Extrasynaptic NMDAR Activity in Neurons, Thus Contributing to Synapse Loss
- (2021) Dorit Trudler et al. JOURNAL OF NEUROSCIENCE
- Insulin‐degrading enzyme: an ally against metabolic and neurodegenerative diseases
- (2021) Luís Sousa et al. JOURNAL OF PATHOLOGY
- The PRIDE database resources in 2022: a hub for mass spectrometry-based proteomics evidences
- (2021) Yasset Perez-Riverol et al. NUCLEIC ACIDS RESEARCH
- Hsp27 reduces glycation‐induced toxicity and aggregation of alpha‐synuclein
- (2020) Hugo Vicente Miranda et al. FASEB JOURNAL
- Glutamate-induced excitotoxicity in Parkinson's disease: The role of glial cells
- (2020) L. Iovino et al. JOURNAL OF PHARMACOLOGICAL SCIENCES
- The role of astrocytic glutamate transporters GLT-1 and GLAST in neurological disorders: Potential targets for neurotherapeutics
- (2019) Edward Pajarillo et al. NEUROPHARMACOLOGY
- Activation of the unfolded protein response in high glucose treated endothelial cells is mediated by methylglyoxal
- (2019) Zehra Irshad et al. Scientific Reports
- Advanced Glycation End Products Modulate Amyloidogenic APP Processing and Tau Phosphorylation: A Mechanistic Link between Glycation and the Development of Alzheimer’s Disease
- (2018) Kedar Batkulwar et al. ACS Chemical Neuroscience
- Diabetes mellitus and Parkinson disease
- (2018) Gennaro Pagano et al. NEUROLOGY
- Serum amino acid profile in patients with Parkinson’s disease
- (2018) Monika Figura et al. PLoS One
- Alpha-Synuclein Glycation and the Action of Anti-Diabetic Agents in Parkinson’s Disease
- (2018) Annekatrin König et al. Journal of Parkinsons Disease
- Modulation of CaMKIIa-GluN2B interaction in levodopa-induced dyskinesia in 6-OHDA-lesioned Parkinson’s rats
- (2018) Xin-Shi Wang et al. BIOMEDICINE & PHARMACOTHERAPY
- Intermittent low-level lead exposure provokes anxiety, hypertension, autonomic dysfunction and neuroinflammation
- (2018) Liana Shvachiy et al. NEUROTOXICOLOGY
- Beyond Dopamine: GABA, Glutamate, and the Axial Symptoms of Parkinson Disease
- (2018) Ruth L. O'Gorman Tuura et al. Frontiers in Neurology
- STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets
- (2018) Damian Szklarczyk et al. NUCLEIC ACIDS RESEARCH
- Synaptic, Mitochondrial, and Lysosomal Dysfunction in Parkinson’s Disease
- (2018) Maria Nguyen et al. TRENDS IN NEUROSCIENCES
- CaMKII Isoforms in Learning and Memory: Localization and Function
- (2018) Gisela Zalcman et al. Frontiers in Molecular Neuroscience
- Glyoxal and methylglyoxal as urinary markers of diabetes. Determination using a dispersive liquid–liquid microextraction procedure combined with gas chromatography–mass spectrometry
- (2017) M. Pastor-Belda et al. JOURNAL OF CHROMATOGRAPHY A
- Epidemiology of Parkinson’s disease
- (2017) Ole-Bjørn Tysnes et al. JOURNAL OF NEURAL TRANSMISSION
- Increased risk of Parkinson disease with diabetes mellitus in a population-based study
- (2017) Yu-Wan Yang et al. MEDICINE
- α-synuclein interacts with PrPC to induce cognitive impairment through mGluR5 and NMDAR2B
- (2017) Diana G Ferreira et al. NATURE NEUROSCIENCE
- Non-motor features of Parkinson disease
- (2017) Anthony H.V. Schapira et al. NATURE REVIEWS NEUROSCIENCE
- The Synucleinopathies: Twenty Years On
- (2017) Michel Goedert et al. Journal of Parkinsons Disease
- The mechanism of sirtuin 2–mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease
- (2017) Rita Machado de Oliveira et al. PLOS BIOLOGY
- Parkinson disease
- (2017) Werner Poewe et al. Nature Reviews Disease Primers
- Posttranslational modifications of blood-derived alpha-synuclein as biochemical markers for Parkinson’s disease
- (2017) Hugo Vicente Miranda et al. Scientific Reports
- The genetic background of Parkinson's disease: current progress and future prospects
- (2016) K. Kalinderi et al. ACTA NEUROLOGICA SCANDINAVICA
- The clinical symptoms of Parkinson's disease
- (2016) Sigurlaug Sveinbjornsdottir JOURNAL OF NEUROCHEMISTRY
- Mitochondrial dysfunction in Parkinson's disease
- (2016) Anindita Bose et al. JOURNAL OF NEUROCHEMISTRY
- Risk of Parkinson Disease in Diabetes Mellitus
- (2016) Xuejing Yue et al. MEDICINE
- Glycation in Parkinson's disease and Alzheimer's disease
- (2016) Hugo Vicente Miranda et al. MOVEMENT DISORDERS
- The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible
- (2016) Damian Szklarczyk et al. NUCLEIC ACIDS RESEARCH
- Non-motor symptoms in Parkinson's disease
- (2016) Ronald F. Pfeiffer PARKINSONISM & RELATED DISORDERS
- Methylglyoxal can mediate behavioral and neurochemical alterations in rat brain
- (2016) Fernanda Hansen et al. PHYSIOLOGY & BEHAVIOR
- Insulin resistance and Parkinson’s disease: A new target for disease modification?
- (2016) D. Athauda et al. PROGRESS IN NEUROBIOLOGY
- Epidemiology of Parkinson's disease
- (2016) A. Elbaz et al. REVUE NEUROLOGIQUE
- Glutamate neurons are intermixed with midbrain dopamine neurons in nonhuman primates and humans
- (2016) David H. Root et al. Scientific Reports
- Dysregulation of protein phosphatase 2A in parkinson disease and dementia with lewy bodies
- (2016) Hye-Jin Park et al. Annals of Clinical and Translational Neurology
- Glycation potentiates neurodegeneration in models of Huntington’s disease
- (2016) Hugo Vicente Miranda et al. Scientific Reports
- SVD-phy: improved prediction of protein functional associations through singular value decomposition of phylogenetic profiles
- (2015) Andrea Franceschini et al. BIOINFORMATICS
- InteractiVenn: a web-based tool for the analysis of sets through Venn diagrams
- (2015) Henry Heberle et al. BMC BIOINFORMATICS
- The role of methylglyoxal and the glyoxalase system in diabetes and other age-related diseases
- (2015) Dionne E.M. Maessen et al. CLINICAL SCIENCE
- Parkinson's disease
- (2015) Lorraine V Kalia et al. LANCET
- Increased expression of the dopamine transporter leads to loss of dopamine neurons, oxidative stress and l-DOPA reversible motor deficits
- (2015) S.T. Masoud et al. NEUROBIOLOGY OF DISEASE
- Neuroimaging of Parkinson's disease: Expanding views
- (2015) Carol P. Weingarten et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- VPS35 Deficiency or Mutation Causes Dopaminergic Neuronal Loss by Impairing Mitochondrial Fusion and Function
- (2015) Fu-Lei Tang et al. Cell Reports
- Methylglyoxal, the dark side of glycolysis
- (2015) Igor Allaman et al. Frontiers in Neuroscience
- Type 2 diabetes mellitus
- (2015) Ralph A. DeFronzo et al. Nature Reviews Disease Primers
- Measurement of glyoxalase activities
- (2014) Makoto Arai et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Glutamatergic pathways as a target for the treatment of dyskinesias in Parkinson's disease: Figure 1
- (2014) M. Angela Cenci BIOCHEMICAL SOCIETY TRANSACTIONS
- The strong relation between post-hemodialysis blood methylglyoxal levels and post-hemodialysis blood glucose concentration rise
- (2014) Miho Senda et al. Clinical and Experimental Nephrology
- Premotor and nonmotor features of Parkinsonʼs disease
- (2014) Jennifer G. Goldman et al. CURRENT OPINION IN NEUROLOGY
- Theoretical and practical applications of the intracerebroventricular route for CSF sampling and drug administration in CNS drug discovery research: A mini review
- (2014) Andy Kuo et al. JOURNAL OF NEUROSCIENCE METHODS
- Direct and indirect pathways of basal ganglia: a critical reappraisal
- (2014) Paolo Calabresi et al. NATURE NEUROSCIENCE
- Extrasynaptic NMDA Receptor Involvement in Central Nervous System Disorders
- (2014) Matthew P. Parsons et al. NEURON
- STRING v10: protein–protein interaction networks, integrated over the tree of life
- (2014) Damian Szklarczyk et al. NUCLEIC ACIDS RESEARCH
- Dopamine Reduction in the Substantia Nigra of Parkinson's Disease Patients Confirmed by In Vivo Magnetic Resonance Spectroscopic Imaging
- (2014) Adriane Gröger et al. PLoS One
- Interactions of CaMKII with dopamine D2 receptors: roles in levodopa-induced dyskinesia in 6-hydroxydopamine lesioned Parkinson's rats
- (2014) SuFang Zhang et al. Scientific Reports
- Involvement of dopamine loss in extrastriatal basal ganglia nuclei in the pathophysiology of Parkinson’s disease
- (2014) Abdelhamid Benazzouz et al. Frontiers in Aging Neuroscience
- Increased plasma levels of the methylglyoxal in patients with newly diagnosed type 2 diabetes 初诊2型糖尿病患者血浆甲基乙二醛水平升高
- (2014) Xiang Kong et al. Journal of Diabetes
- The glycolytic metabolite methylglyoxal induces changes in vigilance by generating low-amplitude non-REM sleep
- (2013) Vladimira Jakubcakova et al. JOURNAL OF PSYCHOPHARMACOLOGY
- Glycation exacerbates the neuronal toxicity of β-amyloid
- (2013) X-H Li et al. Cell Death & Disease
- Functional Neuroanatomy of the Basal Ganglia
- (2013) J. L. Lanciego et al. Cold Spring Harbor Perspectives in Medicine
- Parkinson's Disease and Parkinsonism: Neuropathology
- (2013) D. W. Dickson Cold Spring Harbor Perspectives in Medicine
- Cognitive deficits in a mouse model of pre-manifest Parkinson’s disease
- (2012) Iddo Magen et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Ca2+/Calmodulin-dependent Protein Kinase IIα (αCaMKII) Controls the Activity of the Dopamine Transporter
- (2012) Thomas Steinkellner et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Glyoxalase 1 increases anxiety by reducing GABAA receptor agonist methylglyoxal
- (2012) Margaret G. Distler et al. JOURNAL OF CLINICAL INVESTIGATION
- Extracellular Alpha-Synuclein Oligomers Modulate Synaptic Transmission and Impair LTP Via NMDA-Receptor Activation
- (2012) M. J. Diogenes et al. JOURNAL OF NEUROSCIENCE
- Relationship between increase in astrocytic GLT-1 glutamate transport and late-LTP
- (2012) J. D. Pita-Almenar et al. LEARNING & MEMORY
- Glutamate-based depression GBD
- (2012) Dennis J. McCarthy et al. MEDICAL HYPOTHESES
- Fiji: an open-source platform for biological-image analysis
- (2012) Johannes Schindelin et al. NATURE METHODS
- The many faces of α-synuclein: from structure and toxicity to therapeutic target
- (2012) Hilal A. Lashuel et al. NATURE REVIEWS NEUROSCIENCE
- Hippocampal Glutamate Level and Glutamate Aspartate Transporter (GLAST) are Up-Regulated in Senior Rat Associated with Isoflurane-Induced Spatial Learning/Memory Impairment
- (2012) Xiangdong Qu et al. NEUROCHEMICAL RESEARCH
- A Progressive Mouse Model of Parkinson’s Disease: The Thy1-aSyn (“Line 61”) Mice
- (2012) Marie-Francoise Chesselet et al. Neurotherapeutics
- STRING v9.1: protein-protein interaction networks, with increased coverage and integration
- (2012) Andrea Franceschini et al. NUCLEIC ACIDS RESEARCH
- A Mutation in VPS35, Encoding a Subunit of the Retromer Complex, Causes Late-Onset Parkinson Disease
- (2011) Alexander Zimprich et al. AMERICAN JOURNAL OF HUMAN GENETICS
- VPS35 Mutations in Parkinson Disease
- (2011) Carles Vilariño-Güell et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Role of the Glyoxalase System in Astrocyte-Mediated Neuroprotection
- (2011) M. Belanger et al. JOURNAL OF NEUROSCIENCE
- Enhanced Phosphatase Activity Attenuates -Synucleinopathy in a Mouse Model
- (2011) K.-W. Lee et al. JOURNAL OF NEUROSCIENCE
- Elevated tonic extracellular dopamine concentration and altered dopamine modulation of synaptic activity precede dopamine loss in the striatum of mice overexpressing human α-synuclein
- (2011) Hoa A. Lam et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Pathological roles of α-synuclein in neurological disorders
- (2011) Kostas Vekrellis et al. LANCET NEUROLOGY
- Glutamate and NMDA receptors activation leads to cerebellar dysfunction and impaired motor coordination in unilateral 6-hydroxydopamine lesioned Parkinson’s rat: functional recovery with bone marrow cells, serotonin and GABA
- (2011) M. S. Nandhu et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Global quantification of mammalian gene expression control
- (2011) Björn Schwanhäusser et al. NATURE
- Synucleinopathies from bench to bedside
- (2011) Andreas Puschmann et al. PARKINSONISM & RELATED DISORDERS
- Glutamatergic mechanisms in the dyskinesias induced by pharmacological dopamine replacement and deep brain stimulation for the treatment of Parkinson's disease
- (2011) Véronique Sgambato-Faure et al. PROGRESS IN NEUROBIOLOGY
- Stroke intervention pathways: NMDA receptors and beyond
- (2011) Ted Weita Lai et al. TRENDS IN MOLECULAR MEDICINE
- Advanced glycation endproducts and their pathogenic roles in neurological disorders
- (2010) Gerald Münch et al. AMINO ACIDS
- Behavioral phenotyping of mouse models of Parkinson's disease
- (2010) Tonya N. Taylor et al. BEHAVIOURAL BRAIN RESEARCH
- Cortical Regulation of Striatal Medium Spiny Neuron Dendritic Remodeling in Parkinsonism: Modulation of Glutamate Release Reverses Dopamine Depletion–Induced Dendritic Spine Loss
- (2010) Bonnie G. Garcia et al. CEREBRAL CORTEX
- Increased plasma methylglyoxal level, inflammation, and vascular endothelial dysfunction in diabetic nephropathy
- (2010) Jianxin Lu et al. CLINICAL BIOCHEMISTRY
- The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored
- (2010) D. Szklarczyk et al. NUCLEIC ACIDS RESEARCH
- A Simple Composite Phenotype Scoring System for Evaluating Mouse Models of Cerebellar Ataxia
- (2010) Stephan J. Guyenet et al. Jove-Journal of Visualized Experiments
- Hyperglycemia and Glycation in Diabetic Complications
- (2009) Anne Negre-Salvayre et al. ANTIOXIDANTS & REDOX SIGNALING
- Glutamate, excitotoxicity, and programmed cell death in parkinson disease
- (2009) W. Michael Caudle et al. EXPERIMENTAL NEUROLOGY
- Delivery of a read-through inducing compound, TC007, lessens the severity of a spinal muscular atrophy animal model
- (2009) Virginia B. Mattis et al. HUMAN MOLECULAR GENETICS
- Parkinson's disease: from monogenic forms to genetic susceptibility factors
- (2009) S. Lesage et al. HUMAN MOLECULAR GENETICS
- The sour side of neurodegenerative disorders: the effects of protein glycation
- (2009) Hugo Vicente Miranda et al. JOURNAL OF PATHOLOGY
- Neuropathological assessment of Parkinson's disease: refining the diagnostic criteria
- (2009) Dennis W Dickson et al. LANCET NEUROLOGY
- Initial clinical manifestations of Parkinson's disease: features and pathophysiological mechanisms
- (2009) Maria C Rodriguez-Oroz et al. LANCET NEUROLOGY
- The adhesive removal test: a sensitive method to assess sensorimotor deficits in mice
- (2009) Valentine Bouet et al. Nature Protocols
- Tests to assess motor phenotype in mice: a user's guide
- (2009) Simon P. Brooks et al. NATURE REVIEWS NEUROSCIENCE
- Elevated Plus Maze for Mice
- (2009) Munekazu Komada et al. Jove-Journal of Visualized Experiments
- Olfactory deficits in mice overexpressing human wildtype -synuclein
- (2008) Sheila M. Fleming et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- STRING 8--a global view on proteins and their functional interactions in 630 organisms
- (2008) L. J. Jensen et al. NUCLEIC ACIDS RESEARCH
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