Neuroimaging evidence of glymphatic system dysfunction in possible REM sleep behavior disorder and Parkinson’s disease

Impaired meningeal lymphatic drainage in patients with idiopathic Parkinson’s disease

(2021) Xue-Bing Ding et al.   NATURE MEDICINE

An immunohistochemical study of lymphatic elements in the human brain

(2021) Éva Mezey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glymphatic clearance function in patients with cerebral small vessel disease

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Sleep-related and diurnal effects on brain diffusivity and cerebrospinal fluid flow

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Slow-wave sleep affects synucleinopathy and regulates proteostatic processes in mouse models of Parkinson’s disease

(2021) Marta M. Morawska et al.   Science Translational Medicine

Impairment of the Glymphatic Pathway and Putative Meningeal Lymphatic Vessels in the Aging Human

(2020) Ying Zhou et al.   ANNALS OF NEUROLOGY

Amyloid-Beta Peptides Trigger Aggregation of Alpha-Synuclein In Vitro

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Rest‐activity Pattern Alterations in Idiopathic REM Sleep Behavior Disorder

(2020) Hongliang Feng et al.   ANNALS OF NEUROLOGY

Dream enactment behavior: review for the clinician

(2020) Marc Baltzan et al.   Journal of Clinical Sleep Medicine

Residual Injurious Symptoms and Its Association with Neurodegenerative Outcomes in Idiopathic Rapid Eye Movement Sleep Behavior Disorder: A Retrospective, Longitudinal Follow‐Up Study

(2020) Jing Wang et al.   MOVEMENT DISORDERS

Safety of Intrathecal Administration of Gadolinium-based Contrast Agents: A Systematic Review and Meta-Analysis

(2020) Mihilkumar Patel et al.   RADIOLOGY

Pituitary Adenylate Cyclase-Activating Polypeptide Attenuates Brain Edema by Protecting Blood–Brain Barrier and Glymphatic System After Subarachnoid Hemorrhage in Rats

(2020) Yuanjian Fang et al.   Neurotherapeutics

Nonrapid eye movement sleep electroencephalographic oscillations in idiopathic rapid eye movement sleep behavior disorder: a study of sleep spindles and slow oscillations

(2020) Jun-Sang Sunwoo et al.   SLEEP

Circadian control of brain glymphatic and lymphatic fluid flow

(2020) Lauren M. Hablitz et al.   Nature Communications

Associations of sleep characteristics with alpha‐synuclein in cerebrospinal fluid in older adults

(2020) Xiao‐Tong Wang et al.   Annals of Clinical and Translational Neurology

Altered glymphatic system in idiopathic normal pressure hydrocephalus

(2020) Yun Jung Bae et al.   PARKINSONISM & RELATED DISORDERS

Dysfunction of the Glymphatic System Might Be Related to Iron Deposition in the Normal Aging Brain

(2020) Wei Zhou et al.   Frontiers in Aging Neuroscience

Blocking meningeal lymphatic drainage aggravates Parkinson’s disease-like pathology in mice overexpressing mutated α-synuclein

(2019) Wenyan Zou et al.   Translational Neurodegeneration

NLRP3 inflammasome inhibition with MCC950 improves diabetes-mediated cognitive impairment and vasoneuronal remodeling after ischemia

(2019) Rebecca Ward et al.   PHARMACOLOGICAL RESEARCH

Sleep in Parkinson’s disease

(2019) Ambra Stefani et al.   NEUROPSYCHOPHARMACOLOGY

Prevalence and clinical aspects of mild cognitive impairment in Parkinson's disease: A meta‐analysis

(2019) Chiara Baiano et al.   MOVEMENT DISORDERS

Coupled electrophysiological, hemodynamic, and cerebrospinal fluid oscillations in human sleep

(2019) Nina E. Fultz et al.   SCIENCE

Intrastriatal injection of preformed alpha-synuclein fibrils alters central and peripheral immune cell profiles in non-transgenic mice

(2019) Rachael H. Earls et al.   Journal of Neuroinflammation

CSF tau and β-amyloid predict cerebral synucleinopathy in autopsied Lewy body disorders

(2018) David J. Irwin et al.   NEUROLOGY

Lymphatic drainage system of the brain: A novel target for intervention of neurological diseases

(2018) Bao-Liang Sun et al.   PROGRESS IN NEUROBIOLOGY

Circadian rhythms of melatonin and peripheral clock gene expression in idiopathic REM sleep behavior disorder

(2018) Kamila Weissová et al.   SLEEP MEDICINE

Local hippocampal fast gamma rhythms precede brain-wide hyperemic patterns during spontaneous rodent REM sleep

(2018) Antoine Bergel et al.   Nature Communications

Aquaporin-4-dependent glymphatic solute transport in the rodent brain

(2018) Humberto Mestre et al.   eLife

Iron-related nigral degeneration influences functional topology mediated by striatal dysfunction in Parkinson's disease

(2018) Xiaojun Guan et al.   NEUROBIOLOGY OF AGING

Evaluation of glymphatic system activity with the diffusion MR technique: diffusion tensor image analysis along the perivascular space (DTI-ALPS) in Alzheimer’s disease cases

(2017) Toshiaki Taoka et al.   JAPANESE JOURNAL OF RADIOLOGY

Neuropathological and genetic correlates of survival and dementia onset in synucleinopathies: a retrospective analysis

(2017) David J Irwin et al.   LANCET NEUROLOGY

REMSleep Behavior Disorder in Parkinson's Disease and Other Synucleinopathies

(2017) Erik K. St Louis et al.   MOVEMENT DISORDERS

Sleep fragmentation and Parkinson's disease pathology in older adults without Parkinson's disease

(2017) Shahmir Sohail et al.   MOVEMENT DISORDERS

Evaluation of glymphatic system activity with the diffusion MR technique: diffusion tensor image analysis along the perivascular space (DTI-ALPS) in Alzheimer’s disease cases

(2017) Toshiaki Taoka et al.   Japanese Journal of Radiology

Human and nonhuman primate meninges harbor lymphatic vessels that can be visualized noninvasively by MRI

(2017) Martina Absinta et al.   eLife

Voluntary Exercise Promotes Glymphatic Clearance of Amyloid Beta and Reduces the Activation of Astrocytes and Microglia in Aged Mice

(2017) Xiao-fei He et al.   Frontiers in Molecular Neuroscience

Current understanding of the molecular mechanisms in Parkinson's disease: Targets for potential treatments

(2017) Panchanan Maiti et al.   Translational Neurodegeneration

Defects in trafficking bridge Parkinson's disease pathology and genetics

(2016) Asa Abeliovich et al.   NATURE

Suppression of glymphatic fluid transport in a mouse model of Alzheimer's disease

(2016) Weiguo Peng et al.   NEUROBIOLOGY OF DISEASE

Deletion of aquaporin-4 in APP/PS1 mice exacerbates brain Aβ accumulation and memory deficits

(2015) Zhiqiang Xu et al.   Molecular Neurodegeneration

The Glymphatic System: A Beginner’s Guide

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Impairment of paravascular clearance pathways in the aging brain

(2014) Benjamin T. Kress et al.   ANNALS OF NEUROLOGY

Autophagy modulates SNCA/α-synuclein release, thereby generating a hostile microenvironment

(2014) Anne-Maria Poehler et al.   Autophagy

The neurobiological basis of cognitive impairment in Parkinson's disease

(2014) Glenda M. Halliday et al.   MOVEMENT DISORDERS

Extracellular α-synuclein—a novel and crucial factor in Lewy body diseases

(2014) He-Jin Lee et al.   Nature Reviews Neurology

Validation study of REM Sleep Behavior Disorder Questionnaire – Hong Kong (RBDQ-HK) in East China

(2014) Si-Si Shen et al.   SLEEP MEDICINE

The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement: Guidelines for reporting observational studies

(2014) Erik von Elm et al.   International Journal of Surgery

Circadian Melatonin Rhythm and Excessive Daytime Sleepiness in Parkinson Disease

(2014) Aleksandar Videnovic et al.   JAMA Neurology

Neuronal vulnerability, pathogenesis, and Parkinson's disease

(2013) David Sulzer et al.   MOVEMENT DISORDERS

Parkinson's disease dementia: convergence of α-synuclein, tau and amyloid-β pathologies

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Sleep Drives Metabolite Clearance from the Adult Brain

(2013) L. Xie et al.   SCIENCE

Neuropathologic substrates of Parkinson disease dementia

(2012) David J. Irwin et al.   ANNALS OF NEUROLOGY

Functional brain activity and presynaptic dopamine uptake in patients with Parkinson's disease and mild cognitive impairment: a cross-sectional study

(2012) Urban Ekman et al.   LANCET NEUROLOGY

A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid  

(2012) J. J. Iliff et al.   Science Translational Medicine

The MOCA: Well-suited screen for cognitive impairment in Parkinson disease

(2011) J. Marinus et al.   NEUROLOGY