The Retinal Renin-Angiotensin-Aldosterone System: Implications for Glaucoma

Compromised blood flow in the optic nerve head after systemic administration of 2 aldosterone in rats: A possible rat model of retinal ganglion cell loss

(2022) Yasushi Wada et al.   CURRENT EYE RESEARCH

A review of potential novel glaucoma therapeutic options independent of intraocular pressure

(2021) Wesam Shamseldin Shalaby et al.   SURVEY OF OPHTHALMOLOGY

Mineralocorticoid receptor antagonism limits experimental choroidal neovascularization and structural changes associated with neovascular age-related macular degeneration

(2019) Min Zhao et al.   Nature Communications

Mineralocorticoid receptor antagonists and kidney diseases: pathophysiological basis

(2019) Jonatan Barrera-Chimal et al.   KIDNEY INTERNATIONAL

The renin angiotensin aldosterone system and its therapeutic targets

(2019) Katrina M. Mirabito Colafella et al.   EXPERIMENTAL EYE RESEARCH

Aldosterone as a mediator of severity in retinal vascular disease: Evidence and potential mechanisms

(2019) Michael J. Allingham et al.   EXPERIMENTAL EYE RESEARCH

Gene expression changes in the retina after systemic administration of aldosterone

(2018) Aoi Ono et al.   JAPANESE JOURNAL OF OPHTHALMOLOGY

Elevated plasma aldosterone levels are associated with a reduction in retinal ganglion cell survival

(2018) Yukari Takasago et al.   JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM

Plasma aldosterone level within the normal range is less associated with cardiovascular and cerebrovascular risk in primary aldosteronism

(2017) Masahiko Murata et al.   JOURNAL OF HYPERTENSION

Prevalence and Clinical Manifestations of Primary Aldosteronism Encountered in Primary Care Practice

(2017) Silvia Monticone et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Adeno-Associated Virus Overexpression of Angiotensin-Converting Enzyme-2 Reverses Diabetic Retinopathy in Type 1 Diabetes in Mice

(2016) James M. Dominguez et al.   AMERICAN JOURNAL OF PATHOLOGY

The expression of Mas-receptor of the renin–angiotensin system in the human eye

(2015) A. Vaajanen et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

SPIRONOLACTONE FOR NONRESOLVING CENTRAL SEROUS CHORIORETINOPATHY

(2015) Elodie Bousquet et al.   RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES

Oxidative stress induces autophagy in response to multiple noxious stimuli in retinal ganglion cells

(2014) Wen-jian Lin et al.   Autophagy

Angiotensin II and Vascular Injury

(2014) Augusto C. Montezano et al.   CURRENT HYPERTENSION REPORTS

Effect of the renin inhibitor aliskiren against retinal ischemia-reperfusion injury

(2014) Kaori Tenkumo et al.   EXPERIMENTAL EYE RESEARCH

Oral Delivery of ACE2/Ang-(1–7) Bioencapsulated in Plant Cells Protects against Experimental Uveitis and Autoimmune Uveoretinitis

(2014) Pollob K Shil et al.   MOLECULAR THERAPY

Dock3 attenuates neural cell death due to NMDA neurotoxicity and oxidative stress in a mouse model of normal tension glaucoma

(2013) K Namekata et al.   CELL DEATH AND DIFFERENTIATION

Long-Term Cardio- and Cerebrovascular Events in Patients With Primary Aldosteronism

(2013) Paolo Mulatero et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Aldosterone: a mediator of retinal ganglion cell death and the potential role in the pathogenesis in normal-tension glaucoma

(2013) E Nitta et al.   Cell Death & Disease

Aldosterone affects blood flow and vascular tone regulated by endothelium-derived NO: therapeutic implications

(2012) Noboru Toda et al.   BRITISH JOURNAL OF PHARMACOLOGY

Neovascularization Is Attenuated With Aldosterone Synthase Inhibition in Rats With Retinopathy

(2012) Devy Deliyanti et al.   HYPERTENSION

Bone involvement in aldosteronism

(2012) Antonio Stefano Salcuni et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Mineralocorticoid receptor is involved in rat and human ocular chorioretinopathy

(2012) Min Zhao et al.   JOURNAL OF CLINICAL INVESTIGATION

The retinal renin–angiotensin system: Roles of angiotensin II and aldosterone

(2012) Jennifer L. Wilkinson-Berka et al.   PEPTIDES

Aldosterone, From (Patho)Physiology to Treatment in Cardiovascular and Renal Damage

(2011) Femke Waanders et al.   Current Vascular Pharmacology

Therapeutic perspectives in hypertension: novel means for renin-angiotensin-aldosterone system modulation and emerging device-based approaches

(2011) T. Unger et al.   EUROPEAN HEART JOURNAL

Activation of the aldosterone/mineralocorticoid receptor system and protective effects of mineralocorticoid receptor antagonism in retinal ischemia-reperfusion injury

(2011) Ye Liu et al.   EXPERIMENTAL EYE RESEARCH

ACE2 and Ang-(1-7) Confer Protection Against Development of Diabetic Retinopathy

(2011) Amrisha Verma et al.   MOLECULAR THERAPY

Aldosterone and inflammation

(2011) Kimberly C Gilbert et al.   Current Opinion in Endocrinology Diabetes and Obesity

Angiotensin-converting enzyme 2 is a key modulator of the renin–angiotensin system in cardiovascular and renal disease

(2010) Chris Tikellis et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Dynamic Observation of Mechanically-Injured Mouse Femoral Artery Reveals an Antiinflammatory Effect of Renin Inhibitor

(2009) Jun Ino et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Erratum: The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2009)—Chapter 2

(2009) Toshio Ogihara et al.   HYPERTENSION RESEARCH

Understanding the Importance of IOP Variables in Glaucoma: A Systematic Review

(2009) Marla B. Sultan et al.   SURVEY OF OPHTHALMOLOGY

Angiotensin-(1-7) and Its Effects in the Kidney

(2009) Marc Dilauro et al.   TheScientificWorldJOURNAL

Cardiovascular Outcomes in Patients With Primary Aldosteronism After Treatment

(2008) Cristiana Catena   ARCHIVES OF INTERNAL MEDICINE

Identification of a Retinal Aldosterone System and the Protective Effects of Mineralocorticoid Receptor Antagonism on Retinal Vascular Pathology

(2008) Jennifer L. Wilkinson-Berka et al.   CIRCULATION RESEARCH

Renin Inhibition by Aliskiren Prevents Atherosclerosis Progression

(2008) Jürg Nussberger et al.   HYPERTENSION

Aldosterone Nongenomically Produces NADPH Oxidase−Dependent Reactive Oxygen Species and Induces Myocyte Apoptosis

(2008) Hironori HAYASHI et al.   HYPERTENSION RESEARCH

Risk Factors Associated with a Low Glomerular Filtration Rate in Primary Aldosteronism

(2008) Martin Reincke et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Renin Inhibition in Hypertension

(2008) Alan H. Gradman et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Risk Factors for Glaucoma Onset and Progression

(2008) Anne L. Coleman et al.   SURVEY OF OPHTHALMOLOGY