Pharmacokinetics, Mass Balance, Excretion, and Tissue Distribution of Plasmalogen Precursor PPI-1011
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Pharmacokinetics, Mass Balance, Excretion, and Tissue Distribution of Plasmalogen Precursor PPI-1011
Authors
Keywords
-
Journal
Frontiers in Cell and Developmental Biology
Volume 10, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2022-04-25
DOI
10.3389/fcell.2022.867138
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Oral Supplementation of an Alkylglycerol Mix Comprising Different Alkyl Chains Effectively Modulates Multiple Endogenous Plasmalogen Species in Mice
- (2021) Sudip Paul et al. Metabolites
- Dietary Ethanolamine Plasmalogen Alleviates DSS-Induced Colitis by Enhancing Colon Mucosa Integrity, Antioxidative Stress, and Anti-inflammatory Responses via Increased Ethanolamine Plasmalogen Molecular Species: Protective Role of Vinyl Ether Linkages
- (2021) Ephantus Nguma et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Plasmalogen Replacement Therapy
- (2021) José Carlos Bozelli et al. Membranes
- Oral batyl alcohol supplementation rescues decreased cardiac conduction in ether phospholipid‐deficient mice
- (2020) Hannes Todt et al. JOURNAL OF INHERITED METABOLIC DISEASE
- TheTMEM189gene encodes plasmanylethanolamine desaturase which introduces the characteristic vinyl ether double bond into plasmalogens
- (2020) Ernst R. Werner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Peroxisomal dysfunction in neurodegenerative diseases
- (2019) Doo Sin Jo et al. ARCHIVES OF PHARMACAL RESEARCH
- Breast milk alkylglycerols sustain beige adipocytes through adipose tissue macrophages
- (2019) Haidong Yu et al. JOURNAL OF CLINICAL INVESTIGATION
- A bacterial light response reveals an orphan desaturase for human plasmalogen synthesis
- (2019) Aránzazu Gallego-García et al. SCIENCE
- Neuroprotection and immunomodulation in the gut of parkinsonian mice with a plasmalogen precursor
- (2019) Jordan Nadeau et al. BRAIN RESEARCH
- Oral administration of a synthetic vinyl-ether plasmalogen normalizes open field activity in a mouse model of rhizomelic chondrodysplasia punctata
- (2019) Wedad Fallatah et al. Disease Models & Mechanisms
- The plasmalogen precursor analog PPI-1011 reduces the development of L-DOPA-induced dyskinesias in de novo MPTP monkeys
- (2018) Mélanie Bourque et al. BEHAVIOURAL BRAIN RESEARCH
- From peroxisomal disorders to common neurodegenerative diseases - the role of ether phospholipids in the nervous system
- (2017) Fabian Dorninger et al. FEBS LETTERS
- Reduced muscle strength in ether lipid-deficient mice is accompanied by altered development and function of the neuromuscular junction
- (2017) Fabian Dorninger et al. JOURNAL OF NEUROCHEMISTRY
- Oral Administration of Ethanolamine Glycerophospholipid Containing a High Level of Plasmalogen Improves Memory Impairment in Amyloid β-Infused Rats
- (2017) Shinji Yamashita et al. LIPIDS
- Efficacy and Blood Plasmalogen Changes by Oral Administration of Plasmalogen in Patients with Mild Alzheimer's Disease and Mild Cognitive Impairment: A Multicenter, Randomized, Double-blind, Placebo-controlled Trial
- (2017) Takehiko Fujino et al. EBioMedicine
- Growth charts for individuals with rhizomelic chondrodysplasia punctata
- (2016) Angela L. Duker et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- The biophysical properties of ethanolamine plasmalogens revealed by atomistic molecular dynamics simulations
- (2016) Tomasz Rog et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Plasmalogen Augmentation Reverses Striatal Dopamine Loss in MPTP Mice
- (2016) Edith Miville-Godbout et al. PLoS One
- Plasmalogen precursor analog treatment reduces levodopa-induced dyskinesias in parkinsonian monkeys
- (2015) Laurent Grégoire et al. BEHAVIOURAL BRAIN RESEARCH
- Alkylglycerol monooxygenase as a potential modulator for PAF synthesis in macrophages
- (2013) Suzumi M. Tokuoka et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Alkylglycerol monooxygenase
- (2013) Katrin Watschinger et al. IUBMB LIFE
- Peroxisomal alterations in Alzheimer’s disease
- (2011) Jianqiu Kou et al. ACTA NEUROPATHOLOGICA
- Oral bioavailability of the ether lipid plasmalogen precursor, PPI-1011, in the rabbit: a new therapeutic strategy for Alzheimer's disease
- (2011) Paul L Wood et al. Lipids in Health and Disease
- In vitro and in vivo plasmalogen replacement evaluations in rhizomelic chrondrodysplasia punctata and Pelizaeus-Merzbacher disease using PPI-1011, an ether lipid plasmalogen precursor
- (2011) Paul L Wood et al. Lipids in Health and Disease
- Cellular diamine levels in cancer chemoprevention: modulation by ibuprofen and membrane plasmalogens
- (2011) Paul L Wood et al. Lipids in Health and Disease
- Targeted metabolomic analyses of cellular models of pelizaeus-merzbacher disease reveal plasmalogen and myo-inositol solute carrier dysfunction
- (2011) Paul L Wood et al. Lipids in Health and Disease
- Unknown
- (2011) Noemi Fabelo et al. MOLECULAR MEDICINE
- Circumventricular organs: Receptive and homeostatic functions and clinical implications
- (2011) E. E. Benarroch NEUROLOGY
- Alkyl-Glycerol Rescues Plasmalogen Levels and Pathology of Ether-Phospholipid Deficient Mice
- (2011) Pedro Brites et al. PLoS One
- Membrane plasmalogen composition and cellular cholesterol regulation: a structure activity study
- (2010) Rishikesh Mankidy et al. Lipids in Health and Disease
- Plasmalogens as a marker of elevated systemic oxidative stress in Parkinson's disease
- (2009) Charalampos Dragonas et al. CLINICAL CHEMISTRY AND LABORATORY MEDICINE
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started