Fibroblast Activation Protein-Alpha is a Prognostic Biomarker Associated With Ferroptosis in Stomach Adenocarcinoma

Regulation of Fibroblast Activation Protein by Transforming Growth Factor Beta-1 in Glioblastoma Microenvironment

(2021) Evzen Krepela et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

LncRNA SNHG16 promotes epithelial-mesenchymal transition by upregulating ITGA6 through miR-488 inhibition in osteosarcoma

(2021) Jie Bu et al.   Journal of Bone Oncology

Targeted literature review on use of tumor mutational burden status and programmed cell death ligand 1 expression to predict outcomes of checkpoint inhibitor treatment

(2020) Tina Krieger et al.   Diagnostic Pathology

CAF secreted miR-522 suppresses ferroptosis and promotes acquired chemo-resistance in gastric cancer

(2020) Haiyang Zhang et al.   Molecular Cancer

m6A regulator-mediated methylation modification patterns and tumor microenvironment infiltration characterization in gastric cancer

(2020) Bo Zhang et al.   Molecular Cancer

Visualizing and interpreting cancer genomics data via the Xena platform

(2020) Mary J. Goldman et al.   NATURE BIOTECHNOLOGY

Fibroblast Activation Protein (FAP) Overexpression Induces Epithelial–Mesenchymal Transition (EMT) in Oral Squamous Cell Carcinoma by Down-Regulating Dipeptidyl Peptidase 9 (DPP9)

(2020) Qing-qing Wu et al.   OncoTargets and Therapy

Engineering Chimeric Antigen Receptor T cells Against Immune Checkpoint Inhibitors PD-1/PD-L1 for Treating Pancreatic Cancer

(2020) Ching-Yao Yang et al.   Molecular Therapy-Oncolytics

Molecular recognition of fibroblast activation protein for diagnostic and therapeutic applications

(2020) Adéla Šimková et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

The role of tumor-associated macrophages in gastric cancer development and their potential as a therapeutic target

(2020) V. Gambardella et al.   CANCER TREATMENT REVIEWS

Gastric cancer

(2020) Elizabeth C Smyth et al.   LANCET

Reshaping the Immune Microenvironment by Oncolytic Herpes Simplex Virus in Murine Pancreatic Ductal Adenocarcinoma

(2020) Liming Zhang et al.   MOLECULAR THERAPY

A Physiological Function for Ferroptosis in Tumor Suppression by the Immune System

(2019) Brent R. Stockwell et al.   Cell Metabolism

Recent Progress in Ferroptosis Inducers for Cancer Therapy

(2019) Chen Liang et al.   ADVANCED MATERIALS

Advances in the treatment of gastric cancer

(2019) David H. Ilson   CURRENT OPINION IN GASTROENTEROLOGY

Physcion 8-O-β-glucopyranoside induced ferroptosis via regulating miR-103a-3p/GLS2 axis in gastric cancer

(2019) Ying Niu et al.   LIFE SCIENCES

Efficacy and safety of anti-PD-1/PD-L1 agents vs chemotherapy in patients with gastric or gastroesophageal junction cancer

(2019) Bi-Cheng Wang et al.   MEDICINE

Emerging Strategies of Cancer Therapy Based on Ferroptosis

(2018) Zheyu Shen et al.   ADVANCED MATERIALS

Comprehensive molecular characterization of clinical responses to PD-1 inhibition in metastatic gastric cancer

(2018) Seung Tae Kim et al.   NATURE MEDICINE

Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response

(2018) Peng Jiang et al.   NATURE MEDICINE

Stromal fibroblast activation protein alpha promotes gastric cancer progression via epithelial-mesenchymal transition through Wnt/ β-catenin pathway

(2018) Jiuyang Liu et al.   BMC CANCER

Fibroblast activation protein-α promotes the growth and migration of lung cancer cells via the PI3K and sonic hedgehog pathways

(2017) Jun Jia et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Immune Activation and Benefit From Avelumab in EBV-Positive Gastric Cancer

(2017) Anshuman Panda et al.   JNCI-Journal of the National Cancer Institute

The immune contexture in cancer prognosis and treatment

(2017) Wolf H. Fridman et al.   Nature Reviews Clinical Oncology

GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses

(2017) Zefang Tang et al.   NUCLEIC ACIDS RESEARCH

Fibroblast Activation Protein-α-Positive Fibroblasts Promote Gastric Cancer Progression and Resistance to Immune Checkpoint Blockade

(2017) Xuyang Wen et al.   ONCOLOGY RESEARCH

Roles of Fibroblast Activation Protein and Hepatocyte Growth Factor Expressions in Angiogenesis and Metastasis of Gastric Cancer

(2017) Li-Ming Gao et al.   PATHOLOGY & ONCOLOGY RESEARCH

Immune Activation and Benefit From Avelumab in EBV-Positive Gastric Cancer

(2017) Anshuman Panda et al.   JNCI-Journal of the National Cancer Institute

Cysteine Dioxygenase 1 Mediates Erastin-Induced Ferroptosis in Human Gastric Cancer Cells

(2017) Shihui Hao et al.   NEOPLASIA

Identification of ACSL4 as a biomarker and contributor of ferroptosis

(2016) Hua Yuan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis

(2016) Valerian E Kagan et al.   Nature Chemical Biology

Cleavage of Type I Collagen by Fibroblast Activation Protein-α Enhances Class A Scavenger Receptor Mediated Macrophage Adhesion

(2016) Anna Mazur et al.   PLoS One

Immunization of stromal cell targeting fibroblast activation protein providing immunotherapy to breast cancer mouse model

(2016) Mingyao Meng et al.   TUMOR BIOLOGY

Ferroptosis is induced following siramesine and lapatinib treatment of breast cancer cells

(2016) S Ma et al.   Cell Death & Disease

Macrophages and Therapeutic Resistance in Cancer

(2015) Brian Ruffell et al.   CANCER CELL

Fibroblast activation protein-α, a stromal cell surface protease, shapes key features of cancer associated fibroblasts through proteome and degradome alterations

(2015) M.M. Koczorowska et al.   Molecular Oncology

The prognostic landscape of genes and infiltrating immune cells across human cancers

(2015) Andrew J Gentles et al.   NATURE MEDICINE

Molecular analysis of gastric cancer identifies subtypes associated with distinct clinical outcomes

(2015) Razvan Cristescu et al.   NATURE MEDICINE

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

(2014) Jose Pedro Friedmann Angeli et al.   NATURE CELL BIOLOGY

Fibroblast activation protein-α promotes ovarian cancer cell proliferation and invasion via extracellular and intracellular signaling mechanisms

(2013) WeiWei Yang et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Effects of the fibroblast activation protein on the invasion and migration of gastric cancer

(2013) Rui-Fen Wang et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Spatiotemporal Dynamics of Intratumoral Immune Cells Reveal the Immune Landscape in Human Cancer

(2013) Gabriela Bindea et al.   IMMUNITY

starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein–RNA interaction networks from large-scale CLIP-Seq data

(2013) Jun-Hao Li et al.   NUCLEIC ACIDS RESEARCH

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

FAP-overexpressing fibroblasts produce an extracellular matrix that enhances invasive velocity and directionality of pancreatic cancer cells

(2011) Hyung-Ok Lee et al.   BMC CANCER

A ceRNA Hypothesis: The Rosetta Stone of a Hidden RNA Language?

(2011) Leonardo Salmena et al.   CELL

Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice

(2009) Angélica M. Santos et al.   JOURNAL OF CLINICAL INVESTIGATION