Targeting long noncoding RNA-AQP4-AS1 for the treatment of retinal neurovascular dysfunction in diabetes mellitus

Targeting Aquaporin-4 Subcellular Localization to Treat Central Nervous System Edema

(2020) Philip Kitchen et al.   CELL

Connexin43 hemichannels: A potential drug target for the treatment of diabetic retinopathy

(2019) Odunayo O. Mugisho et al.   DRUG DISCOVERY TODAY

Long noncoding RNA/circular noncoding RNA–miRNA–mRNA axes in cardiovascular diseases

(2019) Ming Li et al.   LIFE SCIENCES

Upregulation of the lncRNA MEG3 improves cognitive impairment, alleviates neuronal damage, and inhibits activation of astrocytes in hippocampus tissues in Alzheimer's disease through inactivating the PI3K/Akt signaling pathway

(2019) Jiping Yi et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Dopaminergic neuron injury in Parkinson’s disease is mitigated by interfering lncRNA SNHG14 expression to regulate the miR-133b/ α-synuclein pathway

(2019) Li-Min Zhang et al.   Aging-US

New Endovascular Approach for Hypothermia With Intrajugular Cooling and Neuroprotective Effect in Ischemic Stroke

(2019) Yunxia Duan et al.   STROKE

Neurodegeneration in diabetic retinopathy: does it really matter?

(2018) Rafael Simó et al.   DIABETOLOGIA

Altered expression of glutamate transporter-1 and water channel protein aquaporin-4 in human temporal cortex with Alzheimer's disease

(2018) A. Hoshi et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Long noncoding RNA NEXN-AS1 mitigates atherosclerosis by regulating the actin-binding protein NEXN

(2018) Yan-Wei Hu et al.   JOURNAL OF CLINICAL INVESTIGATION

A Unified Pathophysiological Construct of Diabetes and its Complications

(2017) Stanley S. Schwartz et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Association of Perivascular Localization of Aquaporin-4 With Cognition and Alzheimer Disease in Aging Brains

(2017) Douglas M. Zeppenfeld et al.   JAMA Neurology

Neurovascular cross talk in diabetic retinopathy: Pathophysiological roles and therapeutic implications

(2016) Elizabeth P. Moran et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Mechanisms of long noncoding RNA function in development and disease

(2016) Sandra U. Schmitz et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Astrocyte structural reactivity and plasticity in models of retinal detachment

(2016) Gabriel Luna et al.   EXPERIMENTAL EYE RESEARCH

Aquaporin-4 mediates communication between astrocyte and microglia: Implications of neuroinflammation in experimental Parkinson’s disease

(2016) H. Sun et al.   NEUROSCIENCE

The progress in understanding and treatment of diabetic retinopathy

(2016) Alan W. Stitt et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Glia–neuron interactions in the mammalian retina

(2016) Elena Vecino et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Linking Long Noncoding RNA Localization and Function

(2016) Ling-Ling Chen   TRENDS IN BIOCHEMICAL SCIENCES

Diabetic retinopathy

(2016) Tien Y. Wong et al.   Nature Reviews Disease Primers

lncRNA-MIAT Regulates Microvascular Dysfunction by Functioning as a Competing Endogenous RNANovelty and Significance

(2015) Biao Yan et al.   CIRCULATION RESEARCH

Novel approaches for treating diabetic retinopathy based on recent pathogenic evidence

(2015) Rafael Simó et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Dopamine Deficiency Contributes to Early Visual Dysfunction in a Rodent Model of Type 1 Diabetes

(2014) Moe H. Aung et al.   JOURNAL OF NEUROSCIENCE

Aquaporins: important but elusive drug targets

(2014) Alan S. Verkman et al.   NATURE REVIEWS DRUG DISCOVERY

Aquaporin-4 expression contributes to decreases in brain water content during mouse postnatal development

(2013) Xiumiao Li et al.   BRAIN RESEARCH BULLETIN

Long Noncoding RNAs: Cellular Address Codes in Development and Disease

(2013) Pedro J. Batista et al.   CELL

Risk of Geographic Atrophy in the Comparison of Age-related Macular Degeneration Treatments Trials

(2013) Juan E. Grunwald et al.   OPHTHALMOLOGY

Aquaporin 4 knockdown exacerbates streptozotocin-induced diabetic retinopathy through aggravating inflammatory response

(2012) Bei Cui et al.   EXPERIMENTAL EYE RESEARCH

The disturbed blood–brain barrier in human glioblastoma

(2012) Hartwig Wolburg et al.   MOLECULAR ASPECTS OF MEDICINE

Muller Cell-Derived VEGF Is Essential for Diabetes-Induced Retinal Inflammation and Vascular Leakage

(2010) J. Wang et al.   DIABETES

Effect of systemic medications on onset and progression of diabetic retinopathy

(2010) Paolo S. Silva et al.   Nature Reviews Endocrinology