Upregulation of the lncRNA MEG3 improves cognitive impairment, alleviates neuronal damage, and inhibits activation of astrocytes in hippocampus tissues in Alzheimer's disease through inactivating the PI3K/Akt signaling pathway

Effects of single-dose neuropeptide Y on levels of hippocampal BDNF, MDA, GSH, and NO in a rat model of pentylenetetrazole-induced epileptic seizure

(2017) Hale Maral Kir et al.   Bosnian Journal of Basic Medical Sciences

Fenofibrate inhibited pancreatic cancer cells proliferation via activation of p53 mediated by upregulation of LncRNA MEG3

(2016) Duanmin Hu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

LncRNA-MEG3 inhibits cell proliferation of endometrial carcinoma by repressing Notch signaling

(2016) Qingyun Guo et al.   BIOMEDICINE & PHARMACOTHERAPY

Insight into the Epigenetics of Alzheimer's Disease: A Computational Study from Human Interactome

(2016) Paulami Chatterjee et al.   Current Alzheimer Research

Downregulation of the Long Non-Coding RNA Meg3 Promotes Angiogenesis After Ischemic Brain Injury by Activating Notch Signaling

(2016) Juan Liu et al.   MOLECULAR NEUROBIOLOGY

Armored long non-coding RNA MEG3 targeting EGFR based on recombinant MS2 bacteriophage virus-like particles against hepatocellular carcinoma

(2016) Le Chang et al.   Oncotarget

Transcriptional Regulation of lncRNA Genes by Histone Modification in Alzheimer’s Disease

(2016) Guoqiang Wan et al.   Biomed Research International

Down regulated lncRNA MEG3 eliminates mycobacteria in macrophages via autophagy

(2016) Kamlesh Pawar et al.   Scientific Reports

Long noncoding RNA MEG3 is downregulated in cervical cancer and affects cell proliferation and apoptosis by regulating miR-21

(2015) Jun Zhang et al.   CANCER BIOLOGY & THERAPY

Use of Pharmacogenomics and Biomarkers in the Development of New Drugs for Alzheimer Disease in Japan⁎⁎The views expressed in this article are those of the author and do not necessarily reflect the official views of Ministry of Health, Labor, and Welfare, or the Pharmaceuticals Medical Devices Agency of Japan.

(2015) Yasuto Otsubo   CLINICAL THERAPEUTICS

Long non-coding RNAs in Alzheimer's disease

(2015) Zijian Zhang   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Reducing Aβ load and tau phosphorylation: Emerging perspective for treating Alzheimer's disease

(2015) Jaspreet Kalra et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Noncoding RNAs, cytokines, and inflammation-related diseases

(2015) José Luiz Marques-Rocha et al.   FASEB JOURNAL

Computational identification of epigenetically regulated lncRNAs and their associated genes based on integrating genomic data

(2015) Tingting Zhao et al.   FEBS LETTERS

Long non-coding RNA MEG3 functions as a competing endogenous RNA to regulate gastric cancer progression

(2015) Weizhao Peng et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Nanomedicine for the treatment of Alzheimer's disease

(2015) Maria Gregori et al.   Nanomedicine

A review on Alzheimer's disease pathophysiology and its management: an update

(2015) Anil Kumar et al.   Pharmacological Reports

Amyloid biomarkers in Alzheimer's disease

(2015) Kaj Blennow et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Decreased expression of long noncoding RNA MEG3 affects cell proliferation and predicts a poor prognosis in patients with colorectal cancer

(2015) Dan-dan Yin et al.   TUMOR BIOLOGY

MEG3 long noncoding RNA regulates the TGF-β pathway genes through formation of RNA–DNA triplex structures

(2015) Tanmoy Mondal et al.   Nature Communications

The Long Noncoding RNA MEG3 Contributes to Cisplatin Resistance of Human Lung Adenocarcinoma

(2015) Jing Liu et al.   PLoS One

A Network Based Method for Analysis of lncRNA-Disease Associations and Prediction of lncRNAs Implicated in Diseases

(2014) Xiaofei Yang et al.   PLoS One

HuD Regulates Coding and Noncoding RNA to Induce APP→Aβ Processing

(2014) Min-Ju Kang et al.   Cell Reports

TF2LncRNA: Identifying Common Transcription Factors for a List of lncRNA Genes from ChIP-Seq Data

(2014) Qinghua Jiang et al.   Biomed Research International

Concomitant downregulation of the imprinted genes DLK1 and MEG3 at 14q32.2 by epigenetic mechanisms in urothelial carcinoma

(2014) Annemarie Greife et al.   Clinical Epigenetics

Roles of long noncoding RNAs in brain development, functional diversification and neurodegenerative diseases

(2013) Ping Wu et al.   BRAIN RESEARCH BULLETIN

Long Noncoding RNAs: Cellular Address Codes in Development and Disease

(2013) Pedro J. Batista et al.   CELL

MicroRNAs in Alzheimer's disease: differential expression in hippocampus and cell-free cerebrospinal fluid

(2013) Mareike Müller et al.   NEUROBIOLOGY OF AGING

Therapeutics of Alzheimer's disease: Past, present and future

(2013) R. Anand et al.   NEUROPHARMACOLOGY

Long noncoding RNAs in development and disease of the central nervous system

(2013) Shi-Yan Ng et al.   TRENDS IN GENETICS

An intronic ncRNA-dependent regulation of SORL1 expression affecting A  formation is upregulated in post-mortem Alzheimer's disease brain samples

(2012) E. Ciarlo et al.   Disease Models & Mechanisms

Non-coding RNAs in Alzheimer's Disease

(2012) Lin Tan et al.   MOLECULAR NEUROBIOLOGY

Long non-coding RNAs in Huntington's disease neurodegeneration

(2011) Rory Johnson   NEUROBIOLOGY OF DISEASE

microRNA-29 can regulate expression of the long non-coding RNA gene MEG3 in hepatocellular cancer

(2011) C Braconi et al.   ONCOGENE

Long noncoding RNAs and human disease

(2011) Orly Wapinski et al.   TRENDS IN CELL BIOLOGY

A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response

(2010) Maite Huarte et al.   CELL

Glial fibrillary acidic protein is one of the key factors underlying neuron-like elongation in PC12 cells

(2010) MAKI SUGAYA-FUKASAWA et al.   Experimental and Therapeutic Medicine

Long non-coding RNAs: insights into functions

(2009) Tim R. Mercer et al.   NATURE REVIEWS GENETICS

GFAP reactivity, apolipoprotein E redistribution and cholesterol reduction in human astrocytes treated with α-synuclein

(2009) Andrew O. Koob et al.   NEUROSCIENCE LETTERS

Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of β-secretase

(2008) Mohammad Ali Faghihi et al.   NATURE MEDICINE