Microbiota and the gut-brain-axis: Implications for new therapeutic design in the CNS

Alterations in the Gut-Microbial-Inflammasome-Brain Axis in a Mouse Model of Alzheimer’s Disease

(2021) Pradeep K. Shukla et al.   Cells

Gut microbiota alterations affect glioma growth and innate immune cells involved in tumor immunosurveillance in mice

(2020) Giuseppina D'Alessandro et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Dysregulated Gut Homeostasis Observed Prior to the Accumulation of the Brain Amyloid-β in Tg2576 Mice

(2020) Pedram Honarpisheh et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Effects of the probiotic formulation SLAB51 in in vitro and in vivo Parkinson’s disease models

(2020) Vanessa Castelli et al.   Aging-US

Probiotics Alleviate the Progressive Deterioration of Motor Functions in a Mouse Model of Parkinson's Disease

(2020) Tsung-Hsun Hsieh et al.   Brain Sciences

The gut microbiota–brain axis in behaviour and brain disorders

(2020) Livia H. Morais et al.   NATURE REVIEWS MICROBIOLOGY

Glioma and temozolomide induced alterations in gut microbiome

(2020) Anthony Patrizz et al.   Scientific Reports

Neuroprotection of Fasting Mimicking Diet on MPTP-Induced Parkinson’s Disease Mice via Gut Microbiota and Metabolites

(2019) Zhi-Lan Zhou et al.   Neurotherapeutics

Gut Microbe to Brain Signaling: What Happens in Vagus…

(2019) Christine Fülling et al.   NEURON

Impact of microbiota on central nervous system and neurological diseases: the gut-brain axis

(2019) Qianquan Ma et al.   Journal of Neuroinflammation

The antibiotic clofoctol suppresses glioma stem cell proliferation by activating KLF13

(2019) Yan Hu et al.   JOURNAL OF CLINICAL INVESTIGATION

Fecal microbiota transplantation to treat Parkinsonʼs disease with constipation

(2019) Hongli Huang et al.   MEDICINE

Neuroinflammation induced by lipopolysaccharide causes cognitive impairment in mice

(2019) Jiayi Zhao et al.   Scientific Reports

Microbiota-Gut-Brain Axis: New Therapeutic Opportunities

(2019) Caitríona Long-Smith et al.   Annual Review of Pharmacology and Toxicology

Strategies used by bacterial pathogens to cross the blood–brain barrier

(2019) Loic Le Guennec et al.   CELLULAR MICROBIOLOGY

Dietary tryptophan links encephalogenicity of autoreactive T cells with gut microbial ecology

(2019) Jana K. Sonner et al.   Nature Communications

Abnormal gut microbiota composition contributes to cognitive dysfunction in SAMP8 mice

(2018) Gaofeng Zhan et al.   Aging-US

Caspr1 is a host receptor for meningitis-causing Escherichia coli

(2018) Wei-Dong Zhao et al.   Nature Communications

Altered composition of the gut microbiome in patients with drug-resistant epilepsy

(2018) Anjiao Peng et al.   EPILEPSY RESEARCH

Helicobacter pylori Filtrate Induces Alzheimer-Like Tau Hyperphosphorylation by Activating Glycogen Synthase Kinase-3β

(2018) Xiu-Lian Wang et al.   JOURNAL OF ALZHEIMERS DISEASE

Protective roles of intestinal microbiota derived short chain fatty acids in Alzheimer’s disease-type beta-amyloid neuropathological mechanisms

(2017) Lap Ho et al.   Expert Review of Neurotherapeutics

Increasing acetyl-CoA metabolism attenuates injury and alters spinal cord lipid content in mice subjected to experimental autoimmune encephalomyelitis

(2017) Amber C. Chevalier et al.   JOURNAL OF NEUROCHEMISTRY

Sodium butyrate exerts protective effect against Parkinson's disease in mice via stimulation of glucagon like peptide-1

(2017) Jiaming Liu et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

A journey into the brain: insight into how bacterial pathogens cross blood–brain barriers

(2017) Mathieu Coureuil et al.   NATURE REVIEWS MICROBIOLOGY

Gut bacteria from multiple sclerosis patients modulate human T cells and exacerbate symptoms in mouse models

(2017) Egle Cekanaviciute et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lactobacillus reuteriinduces gut intraepithelial CD4+CD8αα+T cells

(2017) Luisa Cervantes-Barragan et al.   SCIENCE

Fecal microbiota transplantation cured epilepsy in a case with Crohn’s disease: The first report

(2017) Zhi He et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Ketogenic diet poses a significant effect on imbalanced gut microbiota in infants with refractory epilepsy

(2017) Gan Xie et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Strength of Neisseria meningitidis binding to endothelial cells requires highly-ordered CD147/β2-adrenoceptor clusters assembled by alpha-actinin-4

(2017) Nawal Maïssa et al.   Nature Communications

Protective roles of intestinal microbiota derived short chain fatty acids in Alzheimer’s disease-type beta-amyloid neuropathological mechanisms

(2017) Lap Ho et al.   Expert Review of Neurotherapeutics

The Immune System Bridges the Gut Microbiota with Systemic Energy Homeostasis: Focus on TLRs, Mucosal Barrier, and SCFAs

(2017) Martina Spiljar et al.   Frontiers in Immunology

New evidences on the altered gut microbiota in autism spectrum disorders

(2017) Francesco Strati et al.   Microbiome

Microbiota Transfer Therapy alters gut ecosystem and improves gastrointestinal and autism symptoms: an open-label study

(2017) Dae-Wook Kang et al.   Microbiome

Alteration of behavior and monoamine levels attributable to Lactobacillus plantarum PS128 in germ-free mice

(2016) Wei-Hsien Liu et al.   BEHAVIOURAL BRAIN RESEARCH

Gut microbiota composition and relapse risk in pediatric MS: A pilot study

(2016) Helen Tremlett et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Acetate mediates a microbiome–brain–β-cell axis to promote metabolic syndrome

(2016) Rachel J. Perry et al.   NATURE

Sodium butyrate attenuates social behavior deficits and modifies the transcription of inhibitory/excitatory genes in the frontal cortex of an autism model

(2016) Neta Kratsman et al.   NEUROPHARMACOLOGY

Depletion of Cultivatable Gut Microbiota by Broad-Spectrum Antibiotic Pretreatment Worsens Outcome After Murine Stroke

(2016) Katarzyna Winek et al.   STROKE

Influence of Tryptophan and Serotonin on Mood and Cognition with a Possible Role of the Gut-Brain Axis

(2016) Trisha Jenkins et al.   Nutrients

Effect of Probiotic Supplementation on Cognitive Function and Metabolic Status in Alzheimer's Disease: A Randomized, Double-Blind and Controlled Trial

(2016) Elmira Akbari et al.   Frontiers in Aging Neuroscience

Gut Microbiota Profiling: Metabolomics Based Approach to Unravel Compounds Affecting Human Health

(2016) Pamela Vernocchi et al.   Frontiers in Microbiology

Normalization of Host Intestinal Mucus Layers Requires Long-Term Microbial Colonization

(2015) Malin E.V. Johansson et al.   Cell Host & Microbe

The effects of intestinal tract bacterial diversity on mortality following allogeneic hematopoietic stem cell transplantation

(2014) Y. Taur et al.   BLOOD

Gut microbiota are related to Parkinson's disease and clinical phenotype

(2014) Filip Scheperjans et al.   MOVEMENT DISORDERS

The gut microbiota influences blood-brain barrier permeability in mice

(2014) V. Braniste et al.   Science Translational Medicine

The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism

(2014) Gary Frost et al.   Nature Communications

An intestinal commensal symbiosis factor controls neuroinflammation via TLR2-mediated CD39 signalling

(2014) Yan Wang et al.   Nature Communications

Colonic Migrating Motor Complexes, High Amplitude Propagating Contractions, Neural Reflexes and the Importance of Neuronal and Mucosal Serotonin

(2014) Terence K Smith et al.   Journal of Neurogastroenterology and Motility

Helicobacter pylori-induced gastric inflammation and gastric cancer

(2013) Fei Wang et al.   CANCER LETTERS

GPR41/FFAR3 and GPR43/FFAR2 as Cosensors for Short-Chain Fatty Acids in Enteroendocrine Cells vs FFAR3 in Enteric Neurons and FFAR2 in Enteric Leukocytes

(2013) Mark K. Nøhr et al.   ENDOCRINOLOGY

Diet rapidly and reproducibly alters the human gut microbiome

(2013) Lawrence A. David et al.   NATURE

The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner

(2012) G Clarke et al.   MOLECULAR PSYCHIATRY

Structure, function and diversity of the healthy human microbiome

(2012)   NATURE

Group B Streptococcus surface proteins as major determinants for meningeal tropism

(2011) Asmaa Tazi et al.   CURRENT OPINION IN MICROBIOLOGY

Short-Chain Fatty Acids Stimulate Glucagon-Like Peptide-1 Secretion via the G-Protein-Coupled Receptor FFAR2

(2011) G. Tolhurst et al.   DIABETES

Hcp Family Proteins Secreted via the Type VI Secretion System Coordinately Regulate Escherichia coli K1 Interaction with Human Brain Microvascular Endothelial Cells

(2011) Yan Zhou et al.   INFECTION AND IMMUNITY

Pathological correlates of gastrointestinal dysfunction in Parkinson's disease

(2011) Maria G. Cersosimo et al.   NEUROBIOLOGY OF DISEASE

Integrin-linked kinase is required for vitronectin-mediated internalization of Streptococcus pneumoniae by host cells

(2009) S. Bergmann et al.   JOURNAL OF CELL SCIENCE

Laminin receptor initiates bacterial contact with the blood brain barrier in experimental meningitis models

(2009) Carlos J. Orihuela et al.   JOURNAL OF CLINICAL INVESTIGATION

The surface-anchored NanA protein promotes pneumococcal brain endothelial cell invasion

(2009) Satoshi Uchiyama et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Eradication of Helicobacter pylori may be beneficial in the management of Alzheimer’s disease

(2009) Jannis Kountouras et al.   JOURNAL OF NEUROLOGY