Genetic Variability of Inflammation and Oxidative Stress Genes Affects Onset, Progression of the Disease and Survival of Patients with Amyotrophic Lateral Sclerosis

Blood-based biomarkers of inflammation in amyotrophic lateral sclerosis

(2022) Kim A. Staats et al.   Molecular Neurodegeneration

CARD8 and IL1B Polymorphisms Influence MRI Brain Patterns in Newborns with Hypoxic-Ischemic Encephalopathy Treated with Hypothermia

(2021) Katarina Esih et al.   Antioxidants

No association of GSTP1 rs1695 polymorphism with amyotrophic lateral sclerosis: A case-control study in the Brazilian population

(2021) Jéssica Barletto de Sousa Barros et al.   PLoS One

Involvement of Astrocytes and microRNA Dysregulation in Neurodegenerative Diseases: From Pathogenesis to Therapeutic Potential

(2021) Yang Bai et al.   Frontiers in Molecular Neuroscience

The Interplay of RNA Binding Proteins, Oxidative Stress and Mitochondrial Dysfunction in ALS

(2021) Jasmine Harley et al.   Antioxidants

The Link between Oxidative Stress, Redox Status, Bioenergetics and Mitochondria in the Pathophysiology of ALS

(2021) Elena Obrador et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Insights into the Pathogenesis of Neurodegenerative Diseases: Focus on Mitochondrial Dysfunction and Oxidative Stress

(2021) Anamaria Jurcau   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Inflammatory profiles relate to survival in subtypes of amyotrophic lateral sclerosis

(2020) Mads Nikolaj Olesen et al.   Neurology-Neuroimmunology & Neuroinflammation

CYLD is a causative gene for frontotemporal dementia – amyotrophic lateral sclerosis

(2020) Carol Dobson-Stone et al.   BRAIN

An miRNA fingerprint using neural-enriched extracellular vesicles from blood plasma: towards a biomarker for amyotrophic lateral sclerosis/motor neuron disease

(2020) Sandra Anne Banack et al.   Open Biology

In amyotrophic lateral sclerosis blood cytokines are altered, but do not correlate with changes in brain topology

(2020) Arianna Polverino et al.   Brain Connectivity

Is Polymorphism in the Apoptosis and Inflammatory Pathway Genes Associated With a Primary Response to Anti-TNF Therapy in Crohn’s Disease Patients?

(2020) Michal Walczak et al.   Frontiers in Pharmacology

PON1 is a disease modifier gene in amyotrophic lateral sclerosis: association of the Q192R polymorphism with bulbar onset and reduced survival

(2019) Federico Verde et al.   NEUROLOGICAL SCIENCES

Genetic variability of inflammation and oxidative stress genes does not play a major role in the occurrence of adverse events of dopaminergic treatment in Parkinson’s disease

(2019) Sara Redenšek et al.   Journal of Neuroinflammation

Update on amyotrophic lateral sclerosis genetics

(2019) David Brenner et al.   CURRENT OPINION IN NEUROLOGY

Cortical Neurotoxic Astrocytes with Early ALS Pathology and miR-146a Deficit Replicate Gliosis Markers of Symptomatic SOD1G93A Mouse Model

(2018) Cátia Gomes et al.   MOLECULAR NEUROBIOLOGY

Inflammation, Immunity and ALS: Etiology and Pathology

(2018) Miles Lyon et al.   MUSCLE & NERVE

Genetic epidemiology of amyotrophic lateral sclerosis: a systematic review and meta-analysis

(2017) Zhang-Yu Zou et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Peroxynitrite Activates the NLRP3 Inflammasome Cascade in SOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis

(2017) Ilaria Bellezza et al.   MOLECULAR NEUROBIOLOGY

Common polymorphisms of chemokine (C-X3-C motif) receptor 1 gene modify amyotrophic lateral sclerosis outcome: A population-based study

(2017) Andrea Calvo et al.   MUSCLE & NERVE

The role of mitochondria in amyotrophic lateral sclerosis

(2017) Emma F. Smith et al.   NEUROSCIENCE LETTERS

Amyotrophic Lateral Sclerosis

(2017) Robert H. Brown et al.   NEW ENGLAND JOURNAL OF MEDICINE

Characterization of Gene Expression Phenotype in Amyotrophic Lateral Sclerosis Monocytes

(2017) Weihua Zhao et al.   JAMA Neurology

Increased peripheral blood inflammatory cytokine levels in amyotrophic lateral sclerosis: a meta-analysis study

(2017) Yang Hu et al.   Scientific Reports

Amyotrophic lateral sclerosis

(2016) Matthew A. White et al.   CURRENT OPINION IN NEUROLOGY

The association between antioxidant enzyme polymorphisms and cerebral palsy after perinatal hypoxic-ischaemic encephalopathy

(2016) Katarina Esih et al.   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

IL-10 Controls Early Microglial Phenotypes and Disease Onset in ALS Caused by Misfolded Superoxide Dismutase 1

(2016) M. Gravel et al.   JOURNAL OF NEUROSCIENCE

Decoding ALS: from genes to mechanism

(2016) J. Paul Taylor et al.   NATURE

C9orf72 is required for proper macrophage and microglial function in mice

(2016) J. G. ORourke et al.   SCIENCE

Two common functional catalase gene polymorphisms (rs1001179 and rs794316) and cancer susceptibility: evidence from 14,942 cancer cases and 43,285 controls

(2016) Kang Liu et al.   Oncotarget

The Role of Catalase C262T Gene Polymorphism in the Susceptibility and Survival of Cancers

(2016) Cheng-Di Wang et al.   Scientific Reports

NLRP3 inflammasome is expressed by astrocytes in the SOD1 mouse model of ALS and in human sporadic ALS patients

(2015) Sonja Johann et al.   GLIA

Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia

(2015) Axel Freischmidt et al.   NATURE NEUROSCIENCE

Genetic analysis of amyotrophic lateral sclerosis in the Slovenian population

(2015) Katarina Vrabec et al.   NEUROBIOLOGY OF AGING

Protective and Toxic Neuroinflammation in Amyotrophic Lateral Sclerosis

(2015) Kristopher G. Hooten et al.   Neurotherapeutics

Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways

(2015) E. T. Cirulli et al.   SCIENCE

Increased in vivo glial activation in patients with amyotrophic lateral sclerosis: Assessed with [11C]-PBR28

(2015) Nicole R. Zürcher et al.   NeuroImage-Clinical

The Role of Oxidative Stress in Neurodegenerative Diseases

(2015) Geon Ha Kim et al.   Experimental Neurobiology

Cytokine polymorphisms are associated with fatigue in adults living with HIV/AIDS

(2014) Kathryn A. Lee et al.   BRAIN BEHAVIOR AND IMMUNITY

Evaluating the levels of interleukin-1 family cytokines in sporadic amyotrophic lateral sclerosis

(2014) Paola Italiani et al.   Journal of Neuroinflammation

Catalase activity in blood fractions of patients with sporadic ALS

(2014) Aleksandra Golenia et al.   Pharmacological Reports

CX3CR1 Is a Modifying Gene of Survival and Progression in Amyotrophic Lateral Sclerosis

(2014) Alan Lopez-Lopez et al.   PLoS One

Molecular mechanism of oxidation-induced TDP-43 RRM1 aggregation and loss of function

(2013) Chung-ke Chang et al.   FEBS LETTERS

The MnSOD Ala16Val SNP: Relevance to human diseases and interaction with environmental factors

(2013) G. Bresciani et al.   FREE RADICAL RESEARCH

Global Epidemiology of Amyotrophic Lateral Sclerosis: A Systematic Review of the Published Literature

(2013) A. Chiò et al.   NEUROEPIDEMIOLOGY

The Ala16Val MnSOD gene polymorphism modulates oxidative response to exercise

(2012) Guilherme Bresciani et al.   CLINICAL BIOCHEMISTRY

Involvement of Immune Response in the Pathogenesis of Amyotrophic Lateral Sclerosis: A Therapeutic Opportunity?

(2012) A. Calvo et al.   CNS & Neurological Disorders-Drug Targets

Oxidative stress, neurodegeneration, and the balance of protein degradation and protein synthesis

(2012) Kalavathi Dasuri et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mechanism of Oxidative Stress in Neurodegeneration

(2012) Sonia Gandhi et al.   Oxidative Medicine and Cellular Longevity

MicroRNA-146a: A Key Regulator of Astrocyte-Mediated Inflammatory Response

(2012) Anand Iyer et al.   PLoS One

The Role of Immune and Inflammatory Mechanisms in ALS

(2011) P. A. McCombe et al.   CURRENT MOLECULAR MEDICINE

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

(2011) R. C. Paolicelli et al.   SCIENCE

Treatment with minocycline after disease onset alters astrocyte reactivity and increases microgliosis in SOD1 mutant mice

(2010) A. Florence Keller et al.   EXPERIMENTAL NEUROLOGY

Mutations of optineurin in amyotrophic lateral sclerosis

(2010) Hirofumi Maruyama et al.   NATURE

Mutant superoxide dismutase 1-induced IL-1  accelerates ALS pathogenesis

(2010) F. Meissner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oxidative stress in ALS: Key role in motor neuron injury and therapeutic target

(2009) Siân C. Barber et al.   FREE RADICAL BIOLOGY AND MEDICINE

Radioisotopic Imaging of Neuroinflammation

(2009) A. Winkeler et al.   JOURNAL OF NUCLEAR MEDICINE

Cellular glutathione peroxidase in human brain: cellular distribution, and its potential role in the degradation of Lewy bodies in Parkinson’s disease and dementia with Lewy bodies

(2008) John H. T. Power et al.   ACTA NEUROPATHOLOGICA

Oxidative stress biomarkers in sporadic ALS

(2008) Hiroshi Mitsumoto et al.   Amyotrophic Lateral Sclerosis

Oxidant–antioxidant imbalance in the erythrocytes of sporadic amyotrophic lateral sclerosis patients correlates with the progression of disease

(2008) G. Nagesh Babu et al.   NEUROCHEMISTRY INTERNATIONAL

Association of paraoxonase gene cluster polymorphisms with ALS in France, Quebec, and Sweden

(2008) P. N. Valdmanis et al.   NEUROLOGY