Deferoxamine Alleviates Osteoarthritis by Inhibiting Chondrocyte Ferroptosis and Activating the Nrf2 Pathway

Iron Overload Is Associated With Accelerated Progression of Osteoarthritis: The Role of DMT1 Mediated Iron Homeostasis

(2021) Xingzhi Jing et al.   Frontiers in Cell and Developmental Biology

Noncoding RNAs: New regulatory code in chondrocyte apoptosis and autophagy

(2020) Siyu Jiang et al.   Wiley Interdisciplinary Reviews-RNA

Inhibition of ferroptosis attenuates busulfan-induced oligospermia in mice

(2020) Xi Zhao et al.   TOXICOLOGY

Chondrocyte ferroptosis contribute to the progression of osteoarthritis

(2020) Xudong Yao et al.   Journal of Orthopaedic Translation

Ferroptosis: the greasy side of cell death

(2019) José Pedro Friedmann-Angeli et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Icariin Protects Bone Marrow Mesenchymal Stem Cells Against Iron Overload Induced Dysfunction Through Mitochondrial Fusion and Fission, PI3K/AKT/mTOR and MAPK Pathways

(2019) Xudong Yao et al.   Frontiers in Pharmacology

Osteoarthritis

(2019) David J Hunter et al.   LANCET

OARSI guidelines for the non-surgical management of knee, hip, and polyarticular osteoarthritis

(2019) R.R. Bannuru et al.   OSTEOARTHRITIS AND CARTILAGE

Astaxanthin protects against osteoarthritis via Nrf2: a guardian of cartilage homeostasis

(2019) Kai Sun et al.   Aging-US

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

(2018) Lorenzo Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Ferroptosis-inducing agents compromise in vitro human islet viability and function

(2018) Antonio Bruni et al.   Cell Death & Disease

Resolving the Role of Lipoxygenases in the Initiation and Execution of Ferroptosis

(2018) Ron Shah et al.   ACS Central Science

Role of GPX4 in ferroptosis and its pharmacological implication

(2018) Tobias M. Seibt et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Development of the Concept of Ferroptosis

(2018) Tal Hirschhorn et al.   FREE RADICAL BIOLOGY AND MEDICINE

Osteoarthritis and the Mediterranean Diet: A Systematic Review

(2018) Isabel Morales-Ivorra et al.   Nutrients

Phospholipid Remodeling in Physiology and Disease

(2018) Bo Wang et al.   Annual Review of Physiology

Hyperlipidaemia and incident osteoarthritis of the hand: a population-based case-control study

(2017) N. Frey et al.   OSTEOARTHRITIS AND CARTILAGE

Serum Lipid Levels and Risk Of Hand Osteoarthritis: The Chingford Prospective Cohort Study

(2017) M. Garcia-Gil et al.   Scientific Reports

Identification of ACSL4 as a biomarker and contributor of ferroptosis

(2016) Hua Yuan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Apoptosis signaling pathways in osteoarthritis and possible protective role of melatonin

(2016) Azam Hosseinzadeh et al.   JOURNAL OF PINEAL RESEARCH

ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

(2016) Sebastian Doll et al.   Nature Chemical Biology

Iron overload in a murine model of hereditary hemochromatosis is associated with accelerated progression of osteoarthritis under mechanical stress

(2016) A. Camacho et al.   OSTEOARTHRITIS AND CARTILAGE

Ferroptosis: Death by Lipid Peroxidation

(2016) Wan Seok Yang et al.   TRENDS IN CELL BIOLOGY

Ferroptosis is induced following siramesine and lapatinib treatment of breast cancer cells

(2016) S Ma et al.   Cell Death & Disease

Osteoarthritis

(2015) S Glyn-Jones et al.   LANCET

Ferroptosis as a p53-mediated activity during tumour suppression

(2015) Le Jiang et al.   NATURE

The Cystine/Glutamate Antiporter System xc− in Health and Disease: From Molecular Mechanisms to Novel Therapeutic Opportunities

(2012) Jan Lewerenz et al.   ANTIOXIDANTS & REDOX SIGNALING

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Hereditary hemochromatosis is characterized by a clinically definable arthropathy that correlates with iron load

(2010) G. J. Carroll et al.   ARTHRITIS AND RHEUMATISM

Blood-induced joint disease: the pathophysiology of hemophilic arthropathy

(2010) L. A. VALENTINO   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The role of synovitis in pathophysiology and clinical symptoms of osteoarthritis

(2010) Jérémie Sellam et al.   Nature Reviews Rheumatology