Ceria-Zirconia nanoparticles reduce intracellular globotriaosylceramide accumulation and attenuate kidney injury by enhancing the autophagy flux in cellular and animal models of Fabry disease

Developments in the treatment of Fabry disease

(2020) Sanne J. Veen et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Key Roles of MiT Transcription Factors in Innate Immunity and Inflammation

(2020) Javier E. Irazoqui   TRENDS IN IMMUNOLOGY

Cerium Oxide Nanoparticles: Advances in Biodistribution, Toxicity, and Preclinical Exploration

(2020) Eudald Casals et al.   Small

AAV2/6 Gene Therapy in a Murine Model of Fabry Disease Results in Supraphysiological Enzyme Activity and Effective Substrate Reduction

(2020) Makiko Yasuda et al.   Molecular Therapy-Methods & Clinical Development

Endothelial TFEB (Transcription Factor EB) Improves Glucose Tolerance via Upregulation of IRS (Insulin Receptor Substrate) 1 and IRS2

(2020) Jinjian Sun et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Impaired autophagic and mitochondrial functions are partially restored by ERT in Gaucher and Fabry diseases

(2019) Margarita M. Ivanova et al.   PLoS One

Improved Efficacy in a Fabry Disease Model Using a Systemic mRNA Liver Depot System as Compared to Enzyme Replacement Therapy

(2019) Frank DeRosa et al.   MOLECULAR THERAPY

Migalastat: A Review in Fabry Disease

(2019) Emma H. McCafferty et al.   DRUGS

NADPH oxidase 4 mediates TGF-β1/Smad signaling pathway induced acute kidney injury in hypoxia

(2019) Sungkwon Cho et al.   PLoS One

mTOR hyperactivity mediates lysosomal dysfunction in Gaucher's disease iPSC-neuronal cells

(2019) Robert A. Brown et al.   Disease Models & Mechanisms

An overview on recent in vivo biological application of cerium oxide nanoparticles

(2019) Baskaran Stephen Inbaraj et al.   Asian Journal of Pharmaceutical Sciences

Silver Nanoparticles Impair Retinoic Acid-Inducible Gene I-Mediated Mitochondrial Antiviral Immunity by Blocking the Autophagic Flux in Lung Epithelial Cells

(2018) Berengere Villeret et al.   ACS Nano

Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion

(2018) Mario Mauthe et al.   Autophagy

OUP accepted manuscript

(2018)   HUMAN MOLECULAR GENETICS

TGF-β-mediated NADPH oxidase 4-dependent oxidative stress promotes colistin-induced acute kidney injury

(2018) Bo Young Jeong et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Fabry disease revisited: Management and treatment recommendations for adult patients

(2018) Alberto Ortiz et al.   MOLECULAR GENETICS AND METABOLISM

Oxidative stress caused by activation of NADPH oxidase 4 promotes contrast-induced acute kidney injury

(2018) Bo Young Jeong et al.   PLoS One

TFEB-driven endocytosis coordinates MTORC1 signaling and autophagy

(2018) Israel C. Nnah et al.   Autophagy

The validation of pharmacogenetics for the identification of Fabry patients to be treated with migalastat

(2016) Elfrida R. Benjamin et al.   GENETICS IN MEDICINE

Cytotoxic Compounds from Juglans sinensis Dode Display Anti-Proliferative Activity by Inducing Apoptosis in Human Cancer Cells

(2016) Yoo Lee et al.   MOLECULES

Mechanisms of silver nanoparticle-induced toxicity and important role of autophagy

(2016) Bin-Hsu Mao et al.   Nanotoxicology

A heterozygous female with Fabry disease due to a novel α-galactosidase A mutation exhibits a unique synaptopodin distribution in vacuolated podocytes

(2015) Naoki Takahashi et al.   CLINICAL NEPHROLOGY

Serum-Mediated Inhibition of Enzyme Replacement Therapy in Fabry Disease

(2015) M. Lenders et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Ceria Nanoparticles Stabilized by Organic Surface Coatings Activate the Lysosome-Autophagy System and Enhance Autophagic Clearance

(2014) Wensi Song et al.   ACS Nano

Silica nanoparticles induce autophagy and endothelial dysfunction via the PI3K/Akt/mTOR signaling pathway

(2014) Duan et al.   International Journal of Nanomedicine

Pain Related Channels Are Differentially Expressed in Neuronal and Non-Neuronal Cells of Glabrous Skin of Fabry Knockout Male Mice

(2014) Jarmila Lakomá et al.   PLoS One

Transcription factor EB (TFEB) is a new therapeutic target for Pompe disease

(2013) Carmine Spampanato et al.   EMBO Molecular Medicine

Long-term outcome of enzyme-replacement therapy in advanced Fabry disease: evidence for disease progression towards serious complications

(2013) F. Weidemann et al.   JOURNAL OF INTERNAL MEDICINE

Dysregulated Autophagy Contributes to Podocyte Damage in Fabry’s Disease

(2013) Max C. Liebau et al.   PLoS One

Cerium Dioxide Nanoparticles Induce Apoptosis and Autophagy in Human Peripheral Blood Monocytes

(2012) Salik Hussain et al.   ACS Nano

Autophagy in lysosomal storage disorders

(2012) Andrew P. Lieberman et al.   Autophagy

Transcriptional Activation of Lysosomal Exocytosis Promotes Cellular Clearance

(2011) Diego L. Medina et al.   DEVELOPMENTAL CELL

Inhibition of MTOR Disrupts Autophagic Flux in Podocytes

(2011) D. P. Cina et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Focal Segmental Glomerulosclerosis

(2011) Vivette D. D'Agati et al.   NEW ENGLAND JOURNAL OF MEDICINE

Suppression of autophagy permits successful enzyme replacement therapy in a lysosomal storage disorder—murine Pompe disease

(2010) Nina Raben et al.   Autophagy

Autophagosome maturation is impaired in Fabry disease

(2010) Marc Chévrier et al.   Autophagy

Oxidative stress in Niemann–Pick disease, type C

(2010) Rao Fu et al.   MOLECULAR GENETICS AND METABOLISM

Globotriaosylsphingosine actions on human glomerular podocytes: implications for Fabry nephropathy

(2010) M. D. Sanchez-Nino et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Fabry disease

(2010) Dominique P Germain   Orphanet Journal of Rare Diseases

Life expectancy and cause of death in males and females with Fabry disease: Findings from the Fabry Registry

(2009) Stephen Waldek et al.   GENETICS IN MEDICINE

Newborn screening for Fabry disease in Taiwan reveals a high incidence of the later-onsetGLAmutation c.936+919G>A (IVS4+919G>A)

(2009) Wuh-Liang Hwu et al.   HUMAN MUTATION

PEGylated Nanoceria as Radical Scavenger with Tunable Redox Chemistry

(2009) Ajay S. Karakoti et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Globotriaosylceramide induces oxidative stress and up-regulates cell adhesion molecule expression in Fabry disease endothelial cells

(2008) Jin-Song Shen et al.   MOLECULAR GENETICS AND METABOLISM