Structural Studies of the Nedd4 WW Domains and Their Selectivity for the Connexin43 (Cx43) Carboxyl Terminus

Degradation of gap junction connexins is regulated by the interaction with Cx43-interacting protein of 75 kDa (CIP75)

(2015) Jennifer L. Kopanic et al.   BIOCHEMICAL JOURNAL

Ischaemia-induced autophagy leads to degradation of gap junction protein connexin43 in cardiomyocytes

(2015) Tania Martins-Marques et al.   BIOCHEMICAL JOURNAL

Heart ischemia results in connexin43 ubiquitination localized at the intercalated discs

(2015) Tânia Martins-Marques et al.   BIOCHIMIE

Connexin43 phosphorylation by PKC and MAPK signals VEGF-mediated gap junction internalization

(2015) Wutigri Nimlamool et al.   MOLECULAR BIOLOGY OF THE CELL

Specific Cx43 phosphorylation events regulate gap junction turnover in vivo

(2014) Joell L. Solan et al.   FEBS LETTERS

Structure and closure of connexin gap junction channels

(2014) Atsunori Oshima   FEBS LETTERS

A 14-3-3 Mode-1 Binding Motif Initiates Gap Junction Internalization During Acute Cardiac Ischemia

(2014) James W. Smyth et al.   TRAFFIC

The connexin43-interacting protein, CIP85, mediates the internalization of connexin43 from the plasma membrane

(2013) Kimberly Cochrane et al.   CELL COMMUNICATION AND ADHESION

Effects of Phosphorylation on the Structure and Backbone Dynamics of the Intrinsically Disordered Connexin43 C-terminal Domain

(2013) Rosslyn Grosely et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteins and Mechanisms Regulating Gap-Junction Assembly, Internalization, and Degradation

(2013) Anastasia F. Thévenin et al.   PHYSIOLOGY

Internalized gap junctions are degraded by autophagy

(2012) John T. Fong et al.   Autophagy

MAPK Phosphorylation of Connexin 43 Promotes Binding of Cyclin E and Smooth Muscle Cell Proliferation

(2012) Scott R. Johnstone et al.   CIRCULATION RESEARCH

Cytoplasmic Amino Acids within the Membrane Interface Region Influence Connexin Oligomerization

(2012) Tekla D. Smith et al.   JOURNAL OF MEMBRANE BIOLOGY

Degradation of Endocytosed Gap Junctions by Autophagosomal and Endo-/lysosomal Pathways: A Perspective

(2012) Matthias M. Falk et al.   JOURNAL OF MEMBRANE BIOLOGY

Ubiquitin-mediated internalization of connexin43 is independent of the canonical endocytic tyrosine-sorting signal

(2011) Steve Catarino et al.   BIOCHEMICAL JOURNAL

WW domain-containing proteins: Retrospectives and the future

(2011) Zaidoun Salah   Frontiers in Bioscience-Landmark

A Smad action turnover switch operated by WW domain readers of a phosphoserine code

(2011) E. Aragon et al.   GENES & DEVELOPMENT

A Proteome-wide, Quantitative Survey of In Vivo Ubiquitylation Sites Reveals Widespread Regulatory Roles

(2011) Sebastian A. Wagner et al.   MOLECULAR & CELLULAR PROTEOMICS

Regulation of gap junction intercellular communication by the ubiquitin system

(2010) Ane Kjenseth et al.   CELLULAR SIGNALLING

NMR structure note: UBA domain of CIP75

(2010) Fabien Kieken et al.   JOURNAL OF BIOMOLECULAR NMR

Eps15 interacts with ubiquitinated Cx43 and mediates its internalization

(2009) Henrique Girão et al.   EXPERIMENTAL CELL RESEARCH

Characterization of the Structure and Intermolecular Interactions between the Connexin40 and Connexin43 Carboxyl-terminal and Cytoplasmic Loop Domains

(2009) Denis Bouvier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ubiquitylation of the gap junction protein connexin-43 signals its trafficking from early endosomes to lysosomes in a process mediated by Hrs and Tsg101

(2009) E. Leithe et al.   JOURNAL OF CELL SCIENCE

Sequence determinants of thermodynamic stability in a WW domain-An all-β-sheet protein

(2009) Marcus Jäger et al.   PROTEIN SCIENCE

Structural Changes in the Carboxyl Terminus of the Gap Junction Protein Connexin40 Caused by the Interaction with c-Src and Zonula Occludens-1

(2008) Denis Bouvier et al.   CELL COMMUNICATION AND ADHESION

Double-membrane gap junction internalization requires the clathrin-mediated endocytic machinery

(2008) Anna M. Gumpert et al.   FEBS LETTERS

Protein secondary structure analyses from circular dichroism spectroscopy: Methods and reference databases

(2007) Lee Whitmore et al.   BIOPOLYMERS