A 14-3-3 Mode-1 Binding Motif Initiates Gap Junction Internalization During Acute Cardiac Ischemia

Specific Cx43 phosphorylation events regulate gap junction turnover in vivo

(2014) Joell L. Solan et al.   FEBS LETTERS

EGF induces efficient Cx43 gap junction endocytosis in mouse embryonic stem cell colonies via phosphorylation of Ser262, Ser279/282, and Ser368

(2014) John T. Fong et al.   FEBS LETTERS

Protein Kinase Cδ-mediated Phosphorylation of Connexin43 Gap Junction Channels Causes Movement within Gap Junctions followed by Vesicle Internalization and Protein Degradation

(2014) Angela C. Cone et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deletion of the last five C-terminal amino acid residues of connexin43 leads to lethal ventricular arrhythmias in mice without affecting coupling via gap junction channels

(2013) Indra Lübkemeier et al.   BASIC RESEARCH IN CARDIOLOGY

Regulation of connexin- and pannexin-based channels by post-translational modifications

(2013) Catheleyne D'hondt et al.   BIOLOGY OF THE CELL

Injury-triggered Akt phosphorylation of Cx43: a ZO-1-driven molecular switch that regulates gap junction size

(2013) C. A. Dunn et al.   JOURNAL OF CELL SCIENCE

Proteins and Mechanisms Regulating Gap-Junction Assembly, Internalization, and Degradation

(2013) Anastasia F. Thévenin et al.   PHYSIOLOGY

The perinexus: Sign-post on the path to a new model of cardiac conduction?

(2013) J. Matthew Rhett et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Autoregulation of Connexin43 Gap Junction Formation by Internally Translated Isoforms

(2013) James W. Smyth et al.   Cell Reports

Actin Cytoskeleton Rest Stops Regulate Anterograde Traffic of Connexin 43 Vesicles to the Plasma Membrane

(2012) James W. Smyth et al.   CIRCULATION RESEARCH

Cx43 Associates with Nav1.5 in the Cardiomyocyte Perinexus

(2012) J. Matthew Rhett et al.   JOURNAL OF MEMBRANE BIOLOGY

The Noncanonical Functions of Cx43 in the Heart

(2012) Esperanza Agullo-Pascual et al.   JOURNAL OF MEMBRANE BIOLOGY

Connexin43 phosphorylation in brain, cardiac, endothelial and epithelial tissues

(2011) Lucrecia Márquez-Rosado et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Enhanced PKCε mediated phosphorylation of connexin43 at serine 368 by a carboxyl-terminal mimetic peptide is dependent on injury

(2011) Joseph A. Palatinus et al.   Channels

Phosphatase-Resistant Gap Junctions Inhibit Pathological Remodeling and Prevent Arrhythmias

(2011) Benjamin F. Remo et al.   CIRCULATION RESEARCH

A Peptide Mimetic of the Connexin43 Carboxyl Terminus Reduces Gap Junction Remodeling and Induced Arrhythmia Following Ventricular Injury

(2011) Michael P. O'Quinn et al.   CIRCULATION RESEARCH

The gap junction life cycle

(2011) James W. Smyth et al.   HEART RHYTHM

Connexin 43 connexon to gap junction transition is regulated by zonula occludens-1

(2011) J. Matthew Rhett et al.   MOLECULAR BIOLOGY OF THE CELL

Membrane Proteins as 14-3-3 Clients in Functional Regulation and Intracellular Transport

(2011) Andrew J. Smith et al.   PHYSIOLOGY

Structural basis of 14-3-3 protein functions

(2011) Tomas Obsil et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Limited forward trafficking of connexin 43 reduces cell-cell coupling in stressed human and mouse myocardium

(2010) James W. Smyth et al.   JOURNAL OF CLINICAL INVESTIGATION

Trafficking and Recycling of the Connexin43 Gap Junction Protein during Mitosis

(2010) Daniela Boassa et al.   TRAFFIC

Interplay between PKC and the MAP kinase pathway in Connexin43 phosphorylation and inhibition of gap junction intercellular communication

(2009) Solveig Sirnes et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cx43 CT domain influences infarct size and susceptibility to ventricular tachyarrhythmias in acute myocardial infarction

(2009) Karen Maass et al.   CARDIOVASCULAR RESEARCH

Structural and Molecular Mechanisms of Gap Junction Remodeling in Epicardial Border Zone Myocytes following Myocardial Infarction

(2009) Fabien Kieken et al.   CIRCULATION RESEARCH

Limiting transport steps and novel interactions of Connexin-43 along the secretory pathway

(2009) Irina V. Majoul et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Mechanisms of Gap Junction Traffic in Health and Disease

(2009) Geoffrey G Hesketh et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Intracellular traffic of the K+channels TASK-1 and TASK-3: role of N- and C-terminal sorting signals and interaction with 14-3-3 proteins

(2009) Marylou Zuzarte et al.   JOURNAL OF PHYSIOLOGY-LONDON

Domain-swapped dimerization of ZO-1 PDZ2 generates specific and regulatory connexin43-binding sites

(2008) Jia Chen et al.   EMBO JOURNAL

Double-membrane gap junction internalization requires the clathrin-mediated endocytic machinery

(2008) Anna M. Gumpert et al.   FEBS LETTERS