What's on the Outside Matters: The Role of the Extracellular Polymeric Substance of Gram-negative Biofilms in Evading Host Immunity and as a Target for Therapeutic Intervention

Impact of Environmental Cues on Staphylococcal Quorum Sensing and Biofilm Development

(2016) Jeffrey S. Kavanaugh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Role of Efflux and Physiological Adaptation in Biofilm Tolerance and Resistance

(2016) Heleen Van Acker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biofilm Exopolysaccharides of Pathogenic Fungi: Lessons from Bacteria

(2016) Donald C. Sheppard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biofilms and Cyclic di-GMP (c-di-GMP) Signaling: Lessons fromPseudomonas aeruginosaand Other Bacteria

(2016) Martina Valentini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A novel mechanism for the biogenesis of outer membrane vesicles in Gram-negative bacteria

(2016) Sandro Roier et al.   Nature Communications

Biofilm, pathogenesis and prevention—a journey to break the wall: a review

(2015) Priya Gupta et al.   ARCHIVES OF MICROBIOLOGY

Thermal mitigation ofPseudomonas aeruginosabiofilms

(2015) Ann O’Toole et al.   BIOFOULING

PslG, a self-produced glycosyl hydrolase, triggers biofilm disassembly by disrupting exopolysaccharide matrix

(2015) Shan Yu et al.   CELL RESEARCH

Amyloid-DNA Composites of Bacterial Biofilms Stimulate Autoimmunity

(2015) Paul M. Gallo et al.   IMMUNITY

The O-Antigen Capsule of Salmonella enterica Serovar Typhimurium Facilitates Serum Resistance and Surface Expression of FliC

(2015) Joanna M. Marshall et al.   INFECTION AND IMMUNITY

Identification and Characterization of Mutations Conferring Resistance to d-Amino Acids in Bacillus subtilis

(2015) Sara A. Leiman et al.   JOURNAL OF BACTERIOLOGY

Characterization of thePseudomonas aeruginosaGlycoside Hydrolase PslG Reveals That Its Levels Are Critical for Psl Polysaccharide Biosynthesis and Biofilm Formation

(2015) Perrin Baker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Amyloids Keep Quorum-sensing Molecules in Check

(2015) Thomas Seviour et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteome Profiles of Outer Membrane Vesicles and Extracellular Matrix of Pseudomonas aeruginosa Biofilms

(2015) Narciso Couto et al.   JOURNAL OF PROTEOME RESEARCH

Antibodies against the majority subunit of type IV pili disperse nontypeableHaemophilus influenzaebiofilms in a LuxS-dependent manner and confer therapeutic resolution of experimental otitis media

(2015) Laura A. Novotny et al.   MOLECULAR MICROBIOLOGY

d-Amino Acids Do Not Inhibit Biofilm Formation in Staphylococcus aureus

(2015) Sourav Sarkar et al.   PLoS One

Pel is a cationic exopolysaccharide that cross-links extracellular DNA in thePseudomonas aeruginosabiofilm matrix

(2015) Laura K. Jennings et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cationic Peptides Facilitate Iron-induced Mutagenesis in Bacteria

(2015) Alexandro Rodríguez-Rojas et al.   PLoS Genetics

Inhibition of Salmonella enterica Biofilm Formation Using Small-Molecule Adenosine Mimetics

(2014) Jacob A. Koopman et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antibiofilm and Antimicrobial Efficacy of DispersinB®-KSL-W Peptide-Based Wound Gel Against Chronic Wound Infection Associated Bacteria

(2014) Purushottam V. Gawande et al.   CURRENT MICROBIOLOGY

Regulation of biofilm formation inSalmonella entericaserovar Typhimurium

(2014) Roger Simm et al.   Future Microbiology

Peroxiredoxin-Glutaredoxin and Catalase Promote Resistance of Nontypeable Haemophilus influenzae 86-028NP to Oxidants and Survival within Neutrophil Extracellular Traps

(2014) Richard A. Juneau et al.   INFECTION AND IMMUNITY

Toll-Like Receptor 2 and NLRP3 Cooperate To Recognize a Functional Bacterial Amyloid, Curli

(2014) Glenn J. Rapsinski et al.   INFECTION AND IMMUNITY

Incorporation of Phosphorylcholine into the Lipooligosaccharide of Nontypeable Haemophilus influenzae Does Not Correlate with the Level of Biofilm FormationIn Vitro

(2014) Carmen Puig et al.   INFECTION AND IMMUNITY

The Diguanylate Cyclase GcbA Facilitates Pseudomonas aeruginosa Biofilm Dispersion by Activating BdlA

(2014) Olga E. Petrova et al.   JOURNAL OF BACTERIOLOGY

Mixed-species biofilm compromises wound healing by disrupting epidermal barrier function

(2014) Sashwati Roy et al.   JOURNAL OF PATHOLOGY

Cationic Antimicrobial Peptides Promote Microbial Mutagenesis and Pathoadaptation in Chronic Infections

(2014) Dominique H. Limoli et al.   PLoS Pathogens

Broad-Spectrum Anti-biofilm Peptide That Targets a Cellular Stress Response

(2014) César de la Fuente-Núñez et al.   PLoS Pathogens

Biofilm-specific extracellular matrix proteins of nontypeableHaemophilus influenzae

(2014) Siva Wu et al.   Pathogens and Disease

The biofilm matrix destabilizers, EDTA and DNaseI, enhance the susceptibility of nontypeableHemophilus influenzaebiofilms to treatment with ampicillin and ciprofloxacin

(2014) Rosalia Cavaliere et al.   MicrobiologyOpen

Extracellular DNA-induced antimicrobial peptide resistance in Salmonella enterica serovar Typhimurium

(2013) Lori Johnson et al.   BMC MICROBIOLOGY

Gallbladder Epithelium as a Niche for Chronic Salmonella Carriage

(2013) Geoffrey Gonzalez-Escobedo et al.   INFECTION AND IMMUNITY

Relative Contributions of Lipooligosaccharide Inner and Outer Core Modifications to Nontypeable Haemophilus influenzae Pathogenesis

(2013) Pau Morey et al.   INFECTION AND IMMUNITY

Pseudomonas aeruginosa Biofilms in Disease

(2013) Lawrence R. Mulcahy et al.   MICROBIAL ECOLOGY

Interactions of Methicillin Resistant Staphylococcus aureus USA300 and Pseudomonas aeruginosa in Polymicrobial Wound Infection

(2013) Irena Pastar et al.   PLoS One

Bacterial Biofilms: Development, Dispersal, and Therapeutic Strategies in the Dawn of the Postantibiotic Era

(2013) M. Kostakioti et al.   Cold Spring Harbor Perspectives in Medicine

Alginate Lyase Exhibits Catalysis-Independent Biofilm Dispersion and Antibiotic Synergy

(2012) John W. Lamppa et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Extensive Reduction of Cell Viability and Enhanced Matrix Production in Pseudomonas aeruginosa PAO1 Flow Biofilms Treated with a d-Amino Acid Mixture

(2012) Zoe Sanchez et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Polysaccharides serve as scaffold of biofilms formed by mucoidPseudomonas aeruginosa

(2012) Liang Yang et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Extracellular DNA within a NontypeableHaemophilus influenzae-Induced Biofilm Binds Human Beta Defensin-3 and Reduces Its Antimicrobial Activity

(2012) Eric A. Jones et al.   Journal of Innate Immunity

Identification of Proteins Associated with the Pseudomonas aeruginosa Biofilm Extracellular Matrix

(2012) Masanori Toyofuku et al.   JOURNAL OF PROTEOME RESEARCH

Pseudomonas aeruginosa biofilms perturb wound resolution and antibiotic tolerance in diabetic mice

(2012) Chase Watters et al.   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

Respiratory Syncytial Virus Promotes Moraxella catarrhalis-Induced Ascending Experimental Otitis Media

(2012) M. Elizabeth Brockson et al.   PLoS One

The Microbiological and Clinical Characteristics of Invasive Salmonella in Gallbladders from Cholecystectomy Patients in Kathmandu, Nepal

(2012) Sabina Dongol et al.   PLoS One

Kinetic analysis and evaluation of the mechanisms involved in the resolution of experimental nontypeable Haemophilus influenzae-induced otitis media after transcutaneous immunization

(2012) Laura A. Novotny et al.   VACCINE

Dps promotes survival of nontypeable Haemophilus influenzae in biofilm communities in vitro and resistance to clearance in vivo

(2012) Bing Pang et al.   Frontiers in Cellular and Infection Microbiology

Structure–activity relationship of 2-hydroxy-2-aryl-2,3-dihydro-imidazo[1,2-a]pyrimidinium salts and 2N-substituted 4(5)-aryl-2-amino-1H-imidazoles as inhibitors of biofilm formation by Salmonella Typhimurium and Pseudomonas aeruginosa

(2011) Hans P.L. Steenackers et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Pseudomonas aeruginosa Psl polysaccharide reduces neutrophil phagocytosis and the oxidative response by limiting complement-mediated opsonization

(2011) Meenu Mishra et al.   CELLULAR MICROBIOLOGY

The ENaC-overexpressing mouse as a model of cystic fibrosis lung disease

(2011) Zhe Zhou et al.   Journal of Cystic Fibrosis

Transcutaneous immunization as preventative and therapeutic regimens to protect against experimental otitis media due to nontypeable Haemophilus influenzae

(2011) L A Novotny et al.   Mucosal Immunology

Biofilms can be dispersed by focusing the immune system on a common family of bacterial nucleoid-associated proteins

(2011) S D Goodman et al.   Mucosal Immunology

Biosynthesis of the Pseudomonas aeruginosa Extracellular Polysaccharides, Alginate, Pel, and Psl

(2011) Michael J. Franklin et al.   Frontiers in Microbiology

Toll-like receptors 1 and 2 cooperatively mediate immune responses to curli, a common amyloid from enterobacterial biofilms

(2010) Çagla Tükel et al.   CELLULAR MICROBIOLOGY

Interspecies bacterial communication as a target for therapy in otitis media

(2010) Chelsie E Armbruster et al.   Expert Review of Anti-Infective Therapy

The Vi Capsular Polysaccharide Prevents Complement Receptor 3-Mediated Clearance ofSalmonella entericaSerotype Typhi

(2010) R. Paul Wilson et al.   INFECTION AND IMMUNITY

Antibiotic resistance of bacterial biofilms

(2010) Niels Høiby et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Flagellated but Not Hyperfimbriated Salmonella enterica Serovar Typhimurium Attaches to and Forms Biofilms on Cholesterol-Coated Surfaces

(2010) R. W. Crawford et al.   JOURNAL OF BACTERIOLOGY

Pseudomonas aeruginosauses a cyclic-di-GMP-regulated adhesin to reinforce the biofilm extracellular matrix

(2010) Bradley R. Borlee et al.   MOLECULAR MICROBIOLOGY

Chronic and acute infection of the gall bladder by Salmonella Typhi: understanding the carrier state

(2010) Geoffrey Gonzalez-Escobedo et al.   NATURE REVIEWS MICROBIOLOGY

Gallstones play a significant role in Salmonella spp. gallbladder colonization and carriage

(2010) R. W. Crawford et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

D-Amino Acids Trigger Biofilm Disassembly

(2010) I. Kolodkin-Gal et al.   SCIENCE

Chinchilla as a robust, reproducible and polymicrobial model of otitis media and its prevention

(2009) Lauren O Bakaletz   Expert Review of Vaccines

SalmonellaInfection of Gallbladder Epithelial Cells Drives Local Inflammation and Injury in a Model of Acute Typhoid Fever

(2009) Alfredo Menendez et al.   JOURNAL OF INFECTIOUS DISEASES

Survival of Bacterial Biofilms within Neutrophil Extracellular Traps Promotes Nontypeable Haemophilus influenzae Persistence in the Chinchilla Model for Otitis Media

(2009) Wenzhou Hong et al.   Journal of Innate Immunity

Revisiting AI-2 Quorum Sensing Inhibitors: Direct Comparison of Alkyl-DPD Analogues and a Natural Product Fimbrolide

(2009) Colin A. Lowery et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Intercellular adhesion and biocide resistance in nontypeable Haemophilus influenzae biofilms

(2009) Era A. Izano et al.   MICROBIAL PATHOGENESIS

Signals, Regulatory Networks, and Materials That Build and Break Bacterial Biofilms

(2009) E. Karatan et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Pseudomonas aeruginosa recognizes and responds aggressively to the presence of polymorphonuclear leukocytes

(2009) M. Alhede et al.   MICROBIOLOGY-SGM

Genetic and biochemical analyses of thePseudomonas aeruginosaPsl exopolysaccharide reveal overlapping roles for polysaccharide synthesis enzymes in Psl and LPS production

(2009) Matthew S. Byrd et al.   MOLECULAR MICROBIOLOGY

Brominated Furanones Inhibit Biofilm Formation by Salmonella enterica Serovar Typhimurium

(2008) J. C. A. Janssens et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

A Fatty Acid Messenger Is Responsible for Inducing Dispersion in Microbial Biofilms

(2008) D. G. Davies et al.   JOURNAL OF BACTERIOLOGY

Disruption of the CFTR Gene Produces a Model of Cystic Fibrosis in Newborn Pigs

(2008) C. S. Rogers et al.   SCIENCE

Extracellular DNA Chelates Cations and Induces Antibiotic Resistance in Pseudomonas aeruginosa Biofilms

(2008) Heidi Mulcahy et al.   PLoS Pathogens