Identification of Neutrophil-Related Factor LCN2 for Predicting Severity of Patients With Influenza A Virus and SARS-CoV-2 Infection

Administration of aerosolized SARS-CoV-2 to K18-hACE2 mice uncouples respiratory infection from fatal neuroinvasion

(2022) Valeria Fumagalli et al.   Science Immunology

COVID-19 immune features revealed by a large-scale single-cell transcriptome atlas

(2021) Xianwen Ren et al.   CELL

Circulating Calprotectin as a Biomarker of COVID-19 Severity

(2021) Michael Mahler et al.   Expert Review of Clinical Immunology

CSF lipocalin-2 increases early in subarachnoid hemorrhage are associated with neuroinflammation and unfavorable outcome

(2021) Fang Yu et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Lipocalin 2 modulates dendritic cell activity and shapes immunity to influenza in a microbiome dependent manner

(2021) Martin L. Watzenboeck et al.   PLoS Pathogens

A TLR7 antagonist restricts interferon-dependent and -independent immunopathology in a mouse model of severe influenza

(2021) Julie C.F. Rappe et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The emergence, genomic diversity and global spread of SARS-CoV-2

(2021) Juan Li et al.   NATURE

Omicron likely to weaken COVID vaccine protection

(2021) Ewen Callaway   NATURE

Cerebrospinal fluid lipocalin 2 as a novel biomarker for the differential diagnosis of vascular dementia

(2020) Franc Llorens et al.   Nature Communications

Two waves of pro-inflammatory factors are released during the influenza A virus (IAV)-driven pulmonary immunopathogenesis

(2020) Junsong Zhang et al.   PLoS Pathogens

Diversity of locally produced IFN-α subtypes in human nasopharyngeal epithelial cells and mouse lung tissues during influenza virus infection

(2020) Lei Yang et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Viral and host factors related to the clinical outcome of COVID-19

(2020) Xiaonan Zhang et al.   NATURE

Reduction and Functional Exhaustion of T Cells in Patients With Coronavirus Disease 2019 (COVID-19)

(2020) Bo Diao et al.   Frontiers in Immunology

Neutrophil Extracellular Traps (NETs) Contribute to Immunothrombosis in COVID-19 Acute Respiratory Distress Syndrome

(2020) Elizabeth A Middleton et al.   BLOOD

Neutrophil-derived lipocalin-2 in adult-onset Still’s disease: a novel biomarker of disease activity and liver damage

(2020) Jinchao Jia et al.   RHEUMATOLOGY

Dexamethasone, pro‐resolving lipid mediators and resolution of inflammation in COVID‐19

(2020) Evangelos Andreakos et al.   ALLERGY

Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans

(2020) Prabhu S. Arunachalam et al.   SCIENCE

Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes

(2020) Rajendra Karki et al.   CELL

Induction of alarmin S100A8/A9 mediates activation of aberrant neutrophils in the pathogenesis of COVID-19

(2020) Qirui Guo et al.   Cell Host & Microbe

Serum Lipocalin-2/NGAL in Relation to Biomarkers of Inflammation and Cardiac Stretch During Activation of the Renin-Angiotensin-Aldosterone System (RAAS) in HIV

(2019) Milana Bogorodskaya et al.   JOURNAL OF INFECTIOUS DISEASES

Single-Cell RNA Sequencing in Cancer: Lessons Learned and Emerging Challenges

(2019) Mario L. Suvà et al.   MOLECULAR CELL

Dynamic changes of lymphocyte counts in adult patients with severe pandemic H1N1 influenza A

(2019) Yandong Cheng et al.   Journal of Infection and Public Health

Biomarkers of Systemic Inflammation in Ugandan Infants and Children Hospitalized With Respiratory Syncytial Virus Infection

(2019) Julia Sawatzky et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

How to design a single-cell RNA-sequencing experiment: pitfalls, challenges and perspectives

(2018) Alessandra Dal Molin et al.   BRIEFINGS IN BIOINFORMATICS

Hepatocytes and neutrophils cooperatively suppress bacterial infection by differentially regulating lipocalin-2 and neutrophil extracellular traps

(2018) Hongjie Li et al.   HEPATOLOGY

65 years of influenza surveillance by a World Health Organization-coordinated global network

(2018) Thedi Ziegler et al.   Influenza and Other Respiratory Viruses

High Level of Neutrophil Extracellular Traps Correlates With Poor Prognosis of Severe Influenza A Infection

(2018) Liuluan Zhu et al.   JOURNAL OF INFECTIOUS DISEASES

Using single‐cell genomics to understand developmental processes and cell fate decisions

(2018) Jonathan A Griffiths et al.   Molecular Systems Biology

Lipocalin-2 is a pathogenic determinant and biomarker of neuropsychiatric lupus

(2018) Elise V. Mike et al.   JOURNAL OF AUTOIMMUNITY

Serum Amyloid A3 is required for normal lung development and survival following influenza infection

(2018) Jennifer L. Ather et al.   Scientific Reports

Fecal neutrophil gelatinase-associated lipocalin as a biomarker for inflammatory bowel disease

(2017) Silje Thorsvik et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

New fronts emerge in the influenza cytokine storm

(2017) Xi-zhi J. Guo et al.   Seminars in Immunopathology

Lipocalin-2: A Master Mediator of Intestinal and Metabolic Inflammation

(2017) Alexander R. Moschen et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Deletion of Irf3 and Irf7 Genes in Mice Results in Altered Interferon Pathway Activation and Granulocyte-Dominated Inflammatory Responses to Influenza A Infection

(2016) Bastian Hatesuer et al.   Journal of Innate Immunity

Neutrophil Extracellular Traps Go Viral

(2016) Günther Schönrich et al.   Frontiers in Immunology

The cytokine storm of severe influenza and development of immunomodulatory therapy

(2015) Qiang Liu et al.   Cellular & Molecular Immunology

Lipocalin 2-Dependent Inhibition of Mycobacterial Growth in Alveolar Epithelium

(2014) H. Saiga et al.   JOURNAL OF IMMUNOLOGY

A Systems Analysis Identifies a Feedforward Inflammatory Circuit Leading to Lethal Influenza Infection

(2013) Marlène Brandes et al.   CELL

PD-L1 Expression Induced by the 2009 Pandemic Influenza A(H1N1) Virus Impairs the Human T Cell Response

(2013) Nuriban Valero-Pacheco et al.   Clinical & Developmental Immunology

Lipocalin 2 deactivates macrophages and worsens pneumococcal pneumonia outcomes

(2013) Joanna M. Warszawska et al.   JOURNAL OF CLINICAL INVESTIGATION

Lipocalin-2 ameliorates granulocyte functionality

(2012) Andrea Schroll et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Into the Eye of the Cytokine Storm

(2012) J. R. Tisoncik et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Neutrophil Extracellular Traps Directly Induce Epithelial and Endothelial Cell Death: A Predominant Role of Histones

(2012) Mona Saffarzadeh et al.   PLoS One

Increased levels of cytokines and high-mobility group box 1 are associated with the development of severe pneumonia, but not acute encephalopathy, in 2009 H1N1 influenza-infected children

(2011) Yoshinori Ito et al.   CYTOKINE

Urine NGAL Predicts Severity of Acute Kidney Injury After Cardiac Surgery: A Prospective Study

(2008) M. Bennett et al.   Clinical Journal of the American Society of Nephrology