A Novel TNFSF-Based Signature Predicts the Prognosis and Immunosuppressive Status of Lower-Grade Glioma

Chinese Glioma Genome Atlas (CGGA): A Comprehensive Resource with Functional Genomic Data from Chinese Gliomas

(2021) Zheng Zhao et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Agonistic CD40 therapy induces tertiary lymphoid structures but impairs responses to checkpoint blockade in glioma

(2021) Luuk van Hooren et al.   Nature Communications

Tertiary lymphoid structures improve immunotherapy and survival in melanoma

(2020) Rita Cabrita et al.   NATURE

Redefining Tumor-Associated Macrophage Subpopulations and Functions in the Tumor Microenvironment

(2020) Kaiyue Wu et al.   Frontiers in Immunology

Epithelial-to-mesenchymal transition as the driver of changing carcinoma and glioblastoma microenvironment

(2020) Bernarda Majc et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Comprehensive molecular analyses of a TNF family-based signature with regard to prognosis, immune features, and biomarkers for immunotherapy in lung adenocarcinoma

(2020) Chaoqi Zhang et al.   EBioMedicine

Development and Validation of a Tumor Mutation Burden–Related Immune Prognostic Model for Lower-Grade Glioma

(2020) Wen Yin et al.   Frontiers in Oncology

Immune checkpoint molecule herpes virus entry mediator is overexpressed and associated with poor prognosis in human glioblastoma

(2019) Ming-Zhi Han et al.   EBioMedicine

CD30 ligand deficiency accelerates glioma progression by promoting the formation of tumor immune microenvironment

(2019) Jin Duan et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Efficacy of EGFR plus TNF inhibition in a preclinical model of temozolomide-resistant glioblastoma

(2019) Gao Guo et al.   NEURO-ONCOLOGY

An miR-340-5p-macrophage feedback loop modulates the progression and tumor microenvironment of glioblastoma multiforme

(2019) Yunyun Liu et al.   ONCOGENE

Nuclear factor I A promotes temozolomide resistance in glioblastoma via activation of nuclear factor κB pathway

(2019) Xiao Yu et al.   LIFE SCIENCES

Genetic programming of macrophages to perform anti-tumor functions using targeted mRNA nanocarriers

(2019) F. Zhang et al.   Nature Communications

Overexpression of Fn14 in gliomas: tumor progression and poor prognosis

(2018) Dan Tan et al.   Future Oncology

Differential expression of the TWEAK receptor Fn14 in IDH1 wild-type and mutant gliomas

(2018) David S. Hersh et al.   JOURNAL OF NEURO-ONCOLOGY

The TNF receptor family member Fn14 is highly expressed in recurrent glioblastoma and in GBM patient-derived xenografts with acquired temozolomide resistance

(2018) David S Hersh et al.   NEURO-ONCOLOGY

The immune checkpoint, HVEM may contribute to immune escape in non-small cell lung cancer lacking PD-L1 expression

(2018) Shengxiang Ren et al.   LUNG CANCER

Subtype-specific signaling pathways and genomic aberrations associated with prognosis of glioblastoma

(2018) Ae Kyung Park et al.   NEURO-ONCOLOGY

The TNF Family of Ligands and Receptors: Communication Modules in the Immune System and Beyond

(2018) Catherine Dostert et al.   PHYSIOLOGICAL REVIEWS

Rindopepimut with temozolomide for patients with newly diagnosed, EGFRvIII-expressing glioblastoma (ACT IV): a randomised, double-blind, international phase 3 trial

(2017) Michael Weller et al.   LANCET ONCOLOGY

A TNF–JNK–Axl–ERK signaling axis mediates primary resistance to EGFR inhibition in glioblastoma

(2017) Gao Guo et al.   NATURE NEUROSCIENCE

OS10.3 Randomized Phase 3 Study Evaluating the Efficacy and Safety of Nivolumab vs Bevacizumab in Patients With Recurrent Glioblastoma: CheckMate 143

(2017) D. A. Reardon et al.   NEURO-ONCOLOGY

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

(2016) David N. Louis et al.   ACTA NEUROPATHOLOGICA

Complex heatmaps reveal patterns and correlations in multidimensional genomic data

(2016) Zuguang Gu et al.   BIOINFORMATICS

Results from an Integrated Safety Analysis of Urelumab, an Agonist Anti-CD137 Monoclonal Antibody

(2016) Neil H. Segal et al.   CLINICAL CANCER RESEARCH

The Epithelial-to-Mesenchymal Transition-Like Process in Glioblastoma: An Updated Systematic Review and In Silico Investigation

(2016) Isabele C. Iser et al.   MEDICINAL RESEARCH REVIEWS

Epidermal growth factor receptor targeting and challenges in glioblastoma

(2016) Amy Haseley Thorne et al.   NEURO-ONCOLOGY

IDH mutant diffuse and anaplastic astrocytomas have similar age at presentation and little difference in survival: a grading problem for WHO

(2015) David E. Reuss et al.   ACTA NEUROPATHOLOGICA

IDH mutation status and role of WHO grade and mitotic index in overall survival in grade II–III diffuse gliomas

(2015) Adriana Olar et al.   ACTA NEUROPATHOLOGICA

Oligodendroglioma: pathology, molecular mechanisms and markers

(2015) Pieter Wesseling et al.   ACTA NEUROPATHOLOGICA

Clinical impact of herpesvirus entry mediator expression in human hepatocellular carcinoma

(2015) Daisuke Hokuto et al.   EUROPEAN JOURNAL OF CANCER

The prognostic landscape of genes and infiltrating immune cells across human cancers

(2015) Andrew J Gentles et al.   NATURE MEDICINE

Robust enumeration of cell subsets from tissue expression profiles

(2015) Aaron M Newman et al.   NATURE METHODS

ERBB Receptors: From Oncogene Discovery to Basic Science to Mechanism-Based Cancer Therapeutics

(2014) Carlos L. Arteaga et al.   CANCER CELL

Tumoral RANKL activates astrocytes that promote glioma cell invasion through cytokine signaling

(2014) Jun-Kyum Kim et al.   CANCER LETTERS

TGF-β upregulates CD70 expression and induces exhaustion of effector memory T cells in B-cell non-Hodgkin’s lymphoma

(2014) Z-Z Yang et al.   LEUKEMIA

NF- B, an Active Player in Human Cancers

(2014) Y. Xia et al.   Cancer Immunology Research

Prognostic and predictive value of a microRNA signature in stage II colon cancer: a microRNA expression analysis

(2013) Jia-Xing Zhang et al.   LANCET ONCOLOGY

RANKL Employs Distinct Binding Modes to Engage RANK and the Osteoprotegerin Decoy Receptor

(2012) Christopher A. Nelson et al.   STRUCTURE

Triggering of TNFRSF25 promotes CD8+ T-cell responses and anti-tumor immunity

(2011) Tomasz J. Slebioda et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Mutations in CIC and FUBP1 Contribute to Human Oligodendroglioma

(2011) C. Bettegowda et al.   SCIENCE

X-Linked Ectodermal Dysplasia Receptor Is Downregulated in Breast Cancer via Promoter Methylation

(2010) V. Punj et al.   CLINICAL CANCER RESEARCH

TL1A Selectively Enhances IL-12/IL-18-Induced NK Cell Cytotoxicity against NK-Resistant Tumor Targets

(2010) Stephanie C. Heidemann et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Crosstalk of EDA-A2/XEDAR in the p53 Signaling Pathway

(2010) C. Tanikawa et al.   MOLECULAR CANCER RESEARCH

Sustained TL1A expression modulates effector and regulatory T-cell responses and drives intestinal goblet cell hyperplasia

(2010) V Y Taraban et al.   Mucosal Immunology

Glioma cancer stem cells induce immunosuppressive macrophages/microglia

(2010) Adam Wu et al.   NEURO-ONCOLOGY

Therapeutic Inhibition of the Epidermal Growth Factor Receptor in High-Grade Gliomas: Where Do We Stand?

(2009) G. Karpel-Massler et al.   MOLECULAR CANCER RESEARCH

The TNF-Family Receptor DR3 is Essential for Diverse T Cell-Mediated Inflammatory Diseases

(2008) Françoise Meylan et al.   IMMUNITY