Overexpression of Fn14 in gliomas: tumor progression and poor prognosis

Checkpoints in TNF-Induced Cell Death: Implications in Inflammation and Cancer

(2018) Alessandro Annibaldi et al.   TRENDS IN MOLECULAR MEDICINE

Molecular mechanisms and potential prognostic effects of REST and REST4 in glioma

(2017) Cuilin Li et al.   Molecular Medicine Reports

The molecular classification of astrocytic tumors

(2017) Chen-Xue Mao et al.   Oncotarget

Tumor necrosis factor-like weak inducer of apoptosis regulates quadriceps muscle atrophy and fiber-type alteration in a rat model of chronic obstructive pulmonary disease

(2017) Jun-Juan Lu et al.   Tobacco Induced Diseases

CGCG clinical practice guidelines for the management of adult diffuse gliomas

(2016) Tao Jiang et al.   CANCER LETTERS

SGEF Is Regulated via TWEAK/Fn14/NF- B Signaling and Promotes Survival by Modulation of the DNA Repair Response to Temozolomide

(2016) S. P. F. Ensign et al.   MOLECULAR CANCER RESEARCH

TWEAK-Fn14 Influences Neurogenesis Status via Modulating NF-κB in Mice with Spinal Cord Injury

(2016) Jing Xu et al.   MOLECULAR NEUROBIOLOGY

Moving the needle: Optimizing classification for glioma

(2016) Roel G. W. Verhaak   Science Translational Medicine

PREX2 promotes the proliferation, invasion and migration of pancreatic cancer cells by modulating the PI3K signaling pathway

(2016) Jianyi Yang et al.   Oncology Letters

Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas

(2015)   NEW ENGLAND JOURNAL OF MEDICINE

The TWEAK receptor Fn14 is a potential cell surface portal for targeted delivery of glioblastoma therapeutics

(2015) J G Perez et al.   ONCOGENE

Enhanced cytotoxic effect of radiation and temozolomide in malignant glioma cells: targeting PI3K-AKT-mTOR signaling, HSP90 and histone deacetylases

(2014) Eun Jung Choi et al.   BMC CANCER

Gene Body Methylation Can Alter Gene Expression and Is a Therapeutic Target in Cancer

(2014) Xiaojing Yang et al.   CANCER CELL

RNA-seq of 272 gliomas revealed a novel, recurrentPTPRZ1-METfusion transcript in secondary glioblastomas

(2014) Zhao-Shi Bao et al.   GENOME RESEARCH

A neurocentric perspective on glioma invasion

(2014) Vishnu Anand Cuddapah et al.   NATURE REVIEWS NEUROSCIENCE

Practice changing mature results of RTOG study 9802: another positive PCV trial makes adjuvant chemotherapy part of standard of care in low-grade glioma

(2014) M. J. van den Bent   NEURO-ONCOLOGY

A glioma classification scheme based on coexpression modules of EGFR and PDGFRA

(2014) Yingyu Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TWEAK/Fn14 axis: The current paradigm of tissue injury-inducible function in the midst of complexities

(2014) Linda C. Burkly   SEMINARS IN IMMUNOLOGY

TWEAK-Fn14 Cytokine-Receptor Axis: A New Player of Myocardial Remodeling and Cardiac Failure

(2014) Tatyana Novoyatleva et al.   Frontiers in Immunology

The Somatic Genomic Landscape of Glioblastoma

(2013) Cameron W. Brennan et al.   CELL

TWEAK-Independent Fn14 Self-Association and NF-κB Activation Is Mediated by the C-Terminal Region of the Fn14 Cytoplasmic Domain

(2013) Sharron A. N. Brown et al.   PLoS One

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

(2013) J. Gao et al.   Science Signaling

Adjuvant Procarbazine, Lomustine, and Vincristine Chemotherapy in Newly Diagnosed Anaplastic Oligodendroglioma: Long-Term Follow-Up of EORTC Brain Tumor Group Study 26951

(2012) Martin J. van den Bent et al.   JOURNAL OF CLINICAL ONCOLOGY

Cdc42 and the Guanine Nucleotide Exchange Factors Ect2 and Trio Mediate Fn14-Induced Migration and Invasion of Glioblastoma Cells

(2012) S. P. Fortin et al.   MOLECULAR CANCER RESEARCH

Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia

(2012) Marta Kulis et al.   NATURE GENETICS

Molecular classification of gliomas based on whole genome gene expression: a systematic report of 225 samples from the Chinese Glioma Cooperative Group

(2012) Wei Yan et al.   NEURO-ONCOLOGY

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

IDH mutations predict longer survival and response to temozolomide in secondary glioblastoma

(2011) Qi SongTao et al.   CANCER SCIENCE

TWEAK/Fn14 pathway: an immunological switch for shaping tissue responses

(2011) Linda C. Burkly et al.   IMMUNOLOGICAL REVIEWS

TNF-like weak inducer of apoptosis (TWEAK) and TNF-α cooperate in the induction of keratinocyte apoptosis

(2011) Maya Zimmermann et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas

(2010) C. Houillier et al.   NEUROLOGY

Tumor Necrosis Factor-Like Weak Inducer of Apoptosis Stimulation of Glioma Cell Survival Is Dependent on Akt2 Function

(2009) S. P. Fortin et al.   MOLECULAR CANCER RESEARCH

Rembrandt: Helping Personalized Medicine Become a Reality through Integrative Translational Research

(2009) S. Madhavan et al.   MOLECULAR CANCER RESEARCH

Inhibition of PI3K-AKT-mTOR Signaling Sensitizes Melanoma Cells to Cisplatin and Temozolomide

(2008) Tobias Sinnberg et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The TWEAK–Fn14 cytokine–receptor axis: discovery, biology and therapeutic targeting

(2008) Jeffrey A. Winkles   NATURE REVIEWS DRUG DISCOVERY