Synthesis of Trifluoromethylated 4 H ‐1‐Benzopyran Derivatives via Photocatalytic Trifluoromethylation/Oxidation/Conjugate Addition, and Cyclization Sequences of Vinyl Phenols

Electrochemical Oxidative Arylsulfonylation and 1, 2‐Alkyl Shift Sequences of Alkenyl Cyclobutanols for the Synthesis of β‐Sulfonated Cyclopentanones

(2021) Yebin Kim et al.   BULLETIN OF THE KOREAN CHEMICAL SOCIETY

Visible Light Photocatalytic Trifluoromethylation/SET Oxidation/Cycloaddition Sequences of 2‐Vinyl Phenols: Multicomponent Synthesis of 4 H ‐Chromenes

(2021) Jihoon Jang et al.   Asian Journal of Organic Chemistry

Cooperative Photoinduced/Brønsted Acid Catalyzed Cycloaddition of Transient Thioaldehydes and ortho-Quinone Methides toward a Synthesis of Benzo[e][1,3]oxathiines

(2021) Florian Sachse et al.   ORGANIC LETTERS

Catalytic Asymmetric Conjugate Addition/Hydroalkoxylation Sequence: Expeditious Access to Enantioenriched Eight-Membered Cyclic Ether Derivatives

(2021) Suo-Suo Qi et al.   ORGANIC LETTERS

Redesigning Nature: Ruthenium Flavonoid Complexes with Antitumour, Antimicrobial and Cardioprotective Activities

(2021) Nádia E. Santos et al.   MOLECULES

Electrochemical oxidative bromolactonization of unsaturated carboxylic acids with sodium bromide: Synthesis of bromomethylated γ-lactones

(2021) Rabin Kim et al.   TETRAHEDRON LETTERS

Electrochemical Oxidative Selenolactonization of Alkenoic Acids with Diselenides: Synthesis of Selenated γ‐Lactones

(2021) Yebin Kim et al.   Asian Journal of Organic Chemistry

Visible Light-Driven Radical-Mediated C–C Bond Cleavage/Functionalization in Organic Synthesis

(2020) Xiao-Ye Yu et al.   CHEMICAL REVIEWS

Contribution of Organofluorine Compounds to Pharmaceuticals

(2020) Munenori Inoue et al.   ACS Omega

Regioselective C-H Trifluoromethylation of Heteroaromatic Compounds

(2020) Yoichiro Kuninobu et al.   BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN

Organocatalytic Asymmetric Synthesis of Cyclic Compounds Bearing a Trifluoromethylated Stereogenic Center: Recent Developments

(2019) Xiang-Hong He et al.   ADVANCED SYNTHESIS & CATALYSIS

Lewis Base-Catalyzed [4 + 3] Annulation of ortho-Quinone Methides and MBH Carbonates: Synthesis of Functionalized Benzo[b]oxepines Bearing Oxindole Scaffolds

(2019) Ji-Yuan Du et al.   ORGANIC LETTERS

Electrochemical Radical Selenylation/1,2-Carbon Migration and Dowd–Beckwith-Type Ring-Expansion Sequences of Alkenylcyclobutanols

(2019) Yeon Joo Kim et al.   ORGANIC LETTERS

Synthesis of β-Selenylated Cyclopentanones via Photoredox-Catalyzed Selenylation/Ring-Expansion Cascades of Alkenyl Cyclobutanols

(2019) Hye Im Jung et al.   SYNLETT

Electrochemical radical arylsulfonylation/semipinacol rearrangement sequences of alkenylcyclobutanols: Synthesis of β-sulfonated cyclic ketones

(2019) Yeon Joo Kim et al.   TETRAHEDRON LETTERS

Synthesis of β-selenylated ketones via iodine-mediated selenylation/1,2-carbon migration sequences of alkenyl alcohols

(2019) Yubin Kim et al.   TETRAHEDRON LETTERS

Intermolecular Hetero-Diels–Alder Reactions of Photogenerated aza-ortho-Quinone Methides with Aldehydes

(2019) Dong Liang et al.   ORGANIC LETTERS

Establishing Cation and Radical Donor Ability Scales of Electrophilic F, CF3, and SCF3 Transfer Reagents

(2019) Man Li et al.   ACCOUNTS OF CHEMICAL RESEARCH

Modern Approaches for Asymmetric Construction of Carbon–Fluorine Quaternary Stereogenic Centers: Synthetic Challenges and Pharmaceutical Needs

(2018) Yi Zhu et al.   CHEMICAL REVIEWS

Recent advances in the application of Diels–Alder reactions involving o-quinodimethanes, aza-o-quinone methides and o-quinone methides in natural product total synthesis

(2018) Baochao Yang et al.   CHEMICAL SOCIETY REVIEWS

Enantioselective Formal [4+2] Annulation of ortho-Quinone Methides with ortho-Hydroxyphenyl α,β-Unsaturated Compounds

(2018) Jianlin Zhang et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Decarboxylative Alkylation of β-Keto Acids to ortho-Quinone Methides as Reactive Intermediates: Asymmetric Synthesis of 2,4-Diaryl-1-benzopyrans

(2018) Hyun Jung Jeong et al.   ORGANIC LETTERS

Recent Developments in Visible-Light-Catalyzed Multicomponent Trifluoromethylation of Unsaturated Carbon–Carbon Bonds

(2018) Hyun Kim et al.   SYNTHESIS-STUTTGART

Synthesis of 2,4-Diaryl-4H -Chromenes via Decarboxylative Alkylation of β-Keto Acids to ortho -Quinone Methides as Reactive Intermediates

(2018) Joo Hee Kim et al.   BULLETIN OF THE KOREAN CHEMICAL SOCIETY

Applications of organocatalysed visible-light photoredox reactions for medicinal chemistry

(2018) Michael K Bogdos et al.   Beilstein Journal of Organic Chemistry

Phosphoric Acid Catalyzed Aldehyde Addition to in Situ Generated o-Quinone Methides: An Enantio- and Diastereoselective Entry toward cis-3,4-Diaryl Dihydrocoumarins

(2018) Matthias Spanka et al.   ORGANIC LETTERS

[4 + 2]-Cycloaddition and 1,4-Addition of ortho-Quinone Methides by a Chiral Crotyl Silane

(2018) Christopher R. Wong et al.   ORGANIC LETTERS

Phosphoric Acid Catalyzed [4 + 1]-Cycloannulation Reaction of ortho-Quinone Methides and Diazoketones: Catalytic, Enantioselective Access toward cis-2,3-Dihydrobenzofurans

(2018) Arun Suneja et al.   ORGANIC LETTERS

Phosphine-Catalyzed Enantioselective [4 + 2] Annulation of o-Quinone Methides with Allene Ketones

(2017) Zhen Wang et al.   ORGANIC LETTERS

Synthesis of Spiroketals by Synergistic Gold and Scandium Catalysis

(2017) Man Liang et al.   ORGANIC LETTERS

Photoredox-Mediated Routes to Radicals: The Value of Catalytic Radical Generation in Synthetic Methods Development

(2017) Jennifer K. Matsui et al.   ACS Catalysis

Catalytic asymmetric substitution of ortho-hydroxybenzyl alcohols with tetronic acid-derived enamines: enantioselective synthesis of tetronic acid-derived diarylmethanes

(2017) Meng-Meng Xu et al.   Organic Chemistry Frontiers

Photoinduced Multicomponent Reactions

(2016) Silvia Garbarino et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organo- and Organometallic-Catalytic Intramolecular [1,5]-Hydride Transfer/Cyclization Process through C(sp3)-H Bond Activation

(2016) Su Jin Kwon et al.   CHEMICAL RECORD

Carbon–Carbon Bond Forming Reactions via Photogenerated Intermediates

(2016) Davide Ravelli et al.   CHEMICAL REVIEWS

Photochemical Approaches to Complex Chemotypes: Applications in Natural Product Synthesis

(2016) Markus D. Kärkäs et al.   CHEMICAL REVIEWS

Dual Catalysis Strategies in Photochemical Synthesis

(2016) Kazimer L. Skubi et al.   CHEMICAL REVIEWS

ChiralN,N′-Dioxide-Scandium(III) Complex-Catalyzed Asymmetric Friedel-Crafts Alkylation Reaction ofortho-Hydroxybenzyl Alcohols with C3-Substituted N-Protected Indoles

(2016) Jianfeng Zheng et al.   CHEMISTRY-A EUROPEAN JOURNAL

Biological importance of structurally diversified chromenes

(2016) Marta Costa et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

1-/2-/3-Fluoroalkyl-substituted indoles, promising medicinally and biologically beneficial compounds: Synthetic routes, significance and potential applications

(2016) Boris I. Usachev   JOURNAL OF FLUORINE CHEMISTRY

Emerging Roles of in Situ Generated Quinone Methides in Metal-Free Catalysis

(2016) Ashley A. Jaworski et al.   JOURNAL OF ORGANIC CHEMISTRY

Photoredox Catalysis in Organic Chemistry

(2016) Megan H. Shaw et al.   JOURNAL OF ORGANIC CHEMISTRY

Ortho-Quinone Methides as Reactive Intermediates in Asymmetric Brønsted Acid Catalyzed Cycloadditions with Unactivated Alkenes by Exclusive Activation of the Electrophile

(2015) Chien-Chi Hsiao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Brønsted acid-catalyzed Friedel–Crafts alkylation of electron-rich arenes with in situ-generated ortho-quinone methides: highly enantioselective synthesis of diarylindolylmethanes and triarylmethanes

(2015) Satyajit Saha et al.   CHEMICAL COMMUNICATIONS

Asymmetric Synthesis of Triarylmethanes by Rhodium-Catalyzed Enantioselective Arylation of Diarylmethylamines with Arylboroxines

(2015) Yinhua Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Carbonylative Cyclization of Aryl Alkenes/Alkenols: A New Reaction Mode for the Synthesis of Electron-Rich Chromanes

(2015) Shuang Li et al.   ORGANIC LETTERS

Organocatalytic Asymmetric Nucleophilic Addition to o-Quinone Methides by Alcohols

(2015) Zengwei Lai et al.   ORGANIC LETTERS

Recent Advances in Catalytic Asymmetric Reactions of o-Quinone Methides

(2015) Jianwei Sun et al.   SYNTHESIS-STUTTGART

The Domestication of ortho-Quinone Methides

(2014) Wen-Ju Bai et al.   ACCOUNTS OF CHEMICAL RESEARCH

Enantio- and Diastereoselective Access to Distant Stereocenters Embedded within Tetrahydroxanthenes: Utilizingortho-Quinone Methides as Reactive Intermediates in Asymmetric Brønsted Acid Catalysis

(2014) Chien-Chi Hsiao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Trifluoromethylation of Alkenes with Concomitant Introduction of Additional Functional Groups

(2014) Hiromichi Egami et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Brønsted Acid Catalyzed, Conjugate Addition of β-Dicarbonyls to In Situ Generatedortho-Quinone Methides-Enantioselective Synthesis of 4-Aryl-4H-Chromenes

(2014) Osama El-Sepelgy et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Formation of All-Carbon Quaternary Stereocenters from Indoles and Tertiary Alcohols Bearing A Directing Group

(2014) Wanxiang Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Advances in Catalytic Enantioselective Fluorination, Mono-, Di-, and Trifluoromethylation, and Trifluoromethylthiolation Reactions

(2014) Xiaoyu Yang et al.   CHEMICAL REVIEWS

Natural and Synthetic Chromenes, Fused Chromenes, and Versatility of Dihydrobenzo[h]chromenes in Organic Synthesis

(2014) Ramendra Pratap et al.   CHEMICAL REVIEWS

Good Partnership between Sulfur and Fluorine: Sulfur-Based Fluorination and Fluoroalkylation Reagents for Organic Synthesis

(2014) Chuanfa Ni et al.   CHEMICAL REVIEWS

Synthetic Methods for Compounds Having CF3–S Units on Carbon by Trifluoromethylation, Trifluoromethylthiolation, Triflylation, and Related Reactions

(2014) Xiu-Hua Xu et al.   CHEMICAL REVIEWS

Trifluoromethyltrimethylsilane: Nucleophilic Trifluoromethylation and Beyond

(2014) Xiao Liu et al.   CHEMICAL REVIEWS

Electrophilic Trifluoromethylation by Use of Hypervalent Iodine Reagents

(2014) Julie Charpentier et al.   CHEMICAL REVIEWS

Asymmetric Synthesis of Tetrahydroquinolines via Saegusa-type Oxidative Enamine Catalysis/1,5-Hydride Transfer/Cyclization Sequences

(2014) Chang Won Suh et al.   Asian Journal of Organic Chemistry

Asymmetric Synthesis of Tetrahydroquinolinesvia1,5-Hydride Transfer/Cyclization Catalyzed by Chiral Primary Amine Catalysts

(2013) Young Ku Kang et al.   ADVANCED SYNTHESIS & CATALYSIS

Introduction of Fluorine and Fluorine-Containing Functional Groups

(2013) Theresa Liang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective organocatalytic oxidative enamine catalysis–1,5-hydride transfer–cyclization sequences: asymmetric synthesis of tetrahydroquinolines

(2013) Young Ku Kang et al.   CHEMICAL COMMUNICATIONS

ortho-Quinone Methides in Natural Product Synthesis

(2012) Nicky J. Willis et al.   CHEMISTRY-A EUROPEAN JOURNAL

Palladium(II)-Catalyzed Enantio- and Diastereoselective Synthesis of Pyrrolidine Derivatives

(2012) Ranjan Jana et al.   ORGANIC LETTERS

Microwave assisted synthesis and antimicrobial evaluation of new fused pyran derivatives bearing 2-morpholinoquinoline nucleus

(2011) Jigar A. Makawana et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Structure–Activity Relationship and Molecular Mechanisms of Ethyl 2-Amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate (CXL017) and Its Analogues

(2011) Sonia G. Das et al.   JOURNAL OF MEDICINAL CHEMISTRY

On the Reach of Chemical Synthesis: Creation of a Mini-Pipeline from an Academic Laboratory

(2010) Rebecca M. Wilson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Design and an efficient synthesis of natural product-based cyclopenta[b]pyran derivatives with potential bioactivity

(2010) Changsheng Yao et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design, synthesis and in vitro evaluation of antitubercular and antimicrobial activity of some novel pyranopyrimidines

(2010) Nimesh R. Kamdar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Advancing the Mechanistic Understanding of an Enantioselective Palladium-Catalyzed Alkene Difunctionalization Reaction

(2010) Katrina H. Jensen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis and Preliminary Biological Studies of 3-Substituted Indoles Accessed by a Palladium-Catalyzed Enantioselective Alkene Difunctionalization Reaction

(2010) Tejas P. Pathak et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Organocatalytic C−H Bond Functionalization via Tandem 1,5-Hydride Transfer/Ring Closure: Asymmetric Synthesis of Tetrahydroquinolines

(2010) Young Ku Kang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Enantioselective Addition of Two Distinct Nucleophiles across Alkenes Capable of Quinone Methide Formation

(2009) Katrina H. Jensen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Many Roles for Fluorine in Medicinal Chemistry

(2008) William K. Hagmann   JOURNAL OF MEDICINAL CHEMISTRY

Citrinin Dimers from the Halotolerant FungusPenicillium citrinumB-57

(2008) Zhen-Yu Lu et al.   JOURNAL OF NATURAL PRODUCTS

Total synthesis of tovophyllin B

(2008) Valer Jeso et al.   TETRAHEDRON LETTERS