Bacterial Strategies to Maintain Zinc Metallostasis at the Host-Pathogen Interface

[NiFe]-Hydrogenase Maturation

(2016) Michael J. Lacasse et al.   BIOCHEMISTRY

Salmonella enterica serovar Typhimurium growth is inhibited by the concomitant binding of Zn(II) and a pyrrolyl-hydroxamate to ZnuA, the soluble component of the ZnuABC transporter

(2016) Andrea Ilari et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The Response of Acinetobacter baumannii to Zinc Starvation

(2016) Brittany L. Nairn et al.   Cell Host & Microbe

Functional Determinants of Metal Ion Transport and Selectivity in Paralogous Cation Diffusion Facilitator Transporters CzcD and MntE in Streptococcus pneumoniae

(2016) Julia E. Martin et al.   JOURNAL OF BACTERIOLOGY

Structural Elements in the Transmembrane and Cytoplasmic Domains of the Metal Transporter SLC30A10 Are Required for Its Manganese Efflux Activity

(2016) Charles E. Zogzas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Direct Comparison of Manganese Detoxification/Efflux Proteins and Molecular Characterization of ZnT10 Protein as a Manganese Transporter

(2016) Yukina Nishito et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biosynthesis of a broad-spectrum nicotianamine-like metallophore in Staphylococcus aureus

(2016) G. Ghssein et al.   SCIENCE

Calcium-induced tetramerization and zinc chelation shield human calprotectin from degradation by host and bacterial extracellular proteases

(2016) Jules R. Stephan et al.   Chemical Science

Calcium ions tune the zinc-sequestering properties and antimicrobial activity of human S100A12

(2016) Lisa S. Cunden et al.   Chemical Science

Advances in the molecular understanding of biological zinc transport

(2015) Claudia A. Blindauer   CHEMICAL COMMUNICATIONS

Beyond iron: non-classical biological functions of bacterial siderophores

(2015) Timothy C. Johnstone et al.   DALTON TRANSACTIONS

A sulfur-based transport pathway in Cu+-ATPases

(2015) D. Mattle et al.   EMBO REPORTS

Cation Diffusion Facilitator family: Structure and function

(2015) Olga Kolaj-Robin et al.   FEBS LETTERS

Dual Zinc Transporter Systems in Vibrio cholerae Promote Competitive Advantages over Gut Microbiome

(2015) Ying Sheng et al.   INFECTION AND IMMUNITY

The Human Antimicrobial Protein Calgranulin C Participates in Control of Helicobacter pylori Growth and Regulation of Virulence

(2015) Kathryn P. Haley et al.   INFECTION AND IMMUNITY

Generating a Metal-responsive Transcriptional Regulator to Test What Confers Metal Sensing in Cells

(2015) Deenah Osman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AztD, a Periplasmic Zinc Metallochaperone to an ATP-binding Cassette (ABC) Transporter System inParacoccus denitrificans

(2015) Melody Handali et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Manganese Binding Properties of Human Calprotectin under Conditions of High and Low Calcium: X-ray Crystallographic and Advanced Electron Paramagnetic Resonance Spectroscopic Analysis

(2015) Derek M. Gagnon et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

PfeT, a P1B4-type ATPase, effluxes ferrous iron and protectsBacillus subtilisagainst iron intoxication

(2015) Guohua Guan et al.   MOLECULAR MICROBIOLOGY

Human calprotectin is an iron-sequestering host-defense protein

(2015) Toshiki G Nakashige et al.   Nature Chemical Biology

Allosteric transcriptional regulation via changes in the overall topology of the core promoter

(2015) S. J. Philips et al.   SCIENCE

Dysregulation of transition metal ion homeostasis is the molecular basis for cadmium toxicity in Streptococcus pneumoniae

(2015) Stephanie L. Begg et al.   Nature Communications

The molecular mechanism of Zinc acquisition by the neisserial outer-membrane transporter ZnuD

(2015) Charles Calmettes et al.   Nature Communications

ZnuA and zinc homeostasis in Pseudomonas aeruginosa

(2015) Victoria G. Pederick et al.   Scientific Reports

Metal Preferences and Metallation

(2014) Andrew W. Foster et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Antimicrobial Role for Zinc in Innate Immune Defense Against Group A Streptococcus

(2014) Cheryl-lynn Y. Ong et al.   JOURNAL OF INFECTIOUS DISEASES

Bacillithiol is a major buffer of the labile zinc pool inBacillus subtilis

(2014) Zhen Ma et al.   MOLECULAR MICROBIOLOGY

Structure and mechanism of Zn2+-transporting P-type ATPases

(2014) Kaituo Wang et al.   NATURE

Adhesin competence repressor (AdcR) from Streptococcus pyogenes controls adaptive responses to zinc limitation and contributes to virulence

(2014) Misu Sanson et al.   NUCLEIC ACIDS RESEARCH

Structural and Mechanistic Basis of Zinc Regulation Across the E. coli Zur Regulon

(2014) Benjamin A. Gilston et al.   PLOS BIOLOGY

Biosynthesis of the Urease Metallocenter

(2013) Mark A. Farrugia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Novel P1B-type Mn2+-transporting ATPase Is Required for Secreted Protein Metallation in Mycobacteria

(2013) Teresita Padilla-Benavides et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The ZupT transporter plays an important role in zinc homeostasis and contributes to Salmonella enterica virulence

(2013) Mauro Cerasi et al.   Metallomics

Differential roles for the Co2+/Ni2+transporting ATPases, CtpD and CtpJ, inMycobacterium tuberculosisvirulence

(2013) Daniel Raimunda et al.   MOLECULAR MICROBIOLOGY

Imperfect coordination chemistry facilitates metal ion release in the Psa permease

(2013) Rafael M Couñago et al.   Nature Chemical Biology

New Insights into Histidine Triad Proteins: Solution Structure of a Streptococcus pneumoniae PhtD Domain and Zinc Transfer to AdcAII

(2013) Beate Bersch et al.   PLoS One

Molecular basis for manganese sequestration by calprotectin and roles in the innate immune response to invading bacterial pathogens

(2013) S. M. Damo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inward-facing conformation of the zinc transporter YiiP revealed by cryoelectron microscopy

(2013) N. Coudray et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Zinc Piracy as a Mechanism of Neisseria meningitidis for Evasion of Nutritional Immunity

(2013) Michiel Stork et al.   PLoS Pathogens

Zinc and copper toxicity in host defense against pathogens: Mycobacterium tuberculosis as a model example of an emerging paradigm

(2013) Olivier Neyrolles et al.   Frontiers in Cellular and Infection Microbiology

Mutations in SLC30A10 Cause Parkinsonism and Dystonia with Hypermanganesemia, Polycythemia, and Chronic Liver Disease

(2012) Marialuisa Quadri et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A tetrahedral coordination of Zinc during transmembrane transport by P-type Zn2+-ATPases

(2012) Daniel Raimunda et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Characterization of the Response to Zinc Deficiency in the Cyanobacterium Anabaena sp. Strain PCC 7120

(2012) M. Napolitano et al.   JOURNAL OF BACTERIOLOGY

Cytosolic Ni(II) Sensor in Cyanobacterium

(2012) Andrew W. Foster et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

YeiR: a metal-binding GTPase from Escherichia coli involved in metal homeostasis

(2012) Crysten E. Blaby-Haas et al.   Metallomics

Origins of specificity and cross-talk in metal ion sensing byBacillus subtilisFur

(2012) Zhen Ma et al.   MOLECULAR MICROBIOLOGY

Structural basis for iron piracy by pathogenic Neisseria

(2012) Nicholas Noinaj et al.   NATURE

The siderophore yersiniabactin binds copper to protect pathogens during infection

(2012) Kaveri S Chaturvedi et al.   Nature Chemical Biology

Identification of an Acinetobacter baumannii Zinc Acquisition System that Facilitates Resistance to Calprotectin-mediated Zinc Sequestration

(2012) M. Indriati Hood et al.   PLoS Pathogens

Metalloregulatory proteins: Metal selectivity and allosteric switching

(2011) Hermes Reyes-Caballero et al.   BIOPHYSICAL CHEMISTRY

Mycobacterial P1-Type ATPases Mediate Resistance to Zinc Poisoning in Human Macrophages

(2011) Hélène Botella et al.   Cell Host & Microbe

Crystal Structure of the Zinc-Dependent MarR Family Transcriptional Regulator AdcR in the Zn(II)-Bound State

(2011) Alfredo J. Guerra et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Crystal structure of a copper-transporting PIB-type ATPase

(2011) Pontus Gourdon et al.   NATURE

Sequential binding and sensing of Zn(II) by Bacillus subtilis Zur

(2011) Zhen Ma et al.   NUCLEIC ACIDS RESEARCH

Graded expression of zinc-responsive genes through two regulatory zinc-binding sites in Zur

(2011) J.-H. Shin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histidine Protects Against Zinc and Nickel Toxicity in Caenorhabditis elegans

(2011) John T. Murphy et al.   PLoS Genetics

The Zur-Regulated ZinT Protein Is an Auxiliary Component of the High-Affinity ZnuABC Zinc Transporter That Facilitates Metal Recruitment during Severe Zinc Shortage

(2010) P. Petrarca et al.   JOURNAL OF BACTERIOLOGY

The Metalloregulatory Zinc Site in Streptococcus pneumoniae AdcR, a Zinc-activated MarR Family Repressor

(2010) Hermes Reyes-Caballero et al.   JOURNAL OF MOLECULAR BIOLOGY

Interplay between manganese and zinc homeostasis in the human pathogen Streptococcus pneumoniae

(2010) Faith E. Jacobsen et al.   Metallomics

Role of a Zn-independent DksA in Zn homeostasis and stringent response

(2010) Crysten E. Blaby-Haas et al.   MOLECULAR MICROBIOLOGY

Biosynthesis and functions of bacillithiol, a major low-molecular-weight thiol in Bacilli

(2010) A. Gaballa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A subset of the diverse COG0523 family of putative metal chaperones is linked to zinc homeostasis in all kingdoms of life

(2009) Crysten E Haas et al.   BMC GENOMICS

Coordination Chemistry of Bacterial Metal Transport and Sensing

(2009) Zhen Ma et al.   CHEMICAL REVIEWS

Nutritional immunity beyond iron: a role for manganese and zinc

(2009) Thomas E Kehl-Fie et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Contributions of Zur-Controlled Ribosomal Proteins to Growth under Zinc Starvation Conditions

(2009) S. E. Gabriel et al.   JOURNAL OF BACTERIOLOGY

Zinc-Independent Folate Biosynthesis: Genetic, Biochemical, and Structural Investigations Reveal New Metal Dependence for GTP Cyclohydrolase IB

(2009) B. Sankaran et al.   JOURNAL OF BACTERIOLOGY

Metalloproteins and metal sensing

(2009) Kevin J. Waldron et al.   NATURE

Bacillithiol is an antioxidant thiol produced in Bacilli

(2009) Gerald L Newton et al.   Nature Chemical Biology

A G-protein editor gates coenzyme B12 loading and is corrupted in methylmalonic aciduria

(2009) D. Padovani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Solution structure of a paradigm ArsR family zinc sensor in the DNA-bound state

(2009) A. I. Arunkumar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of the Bacillus subtilis yciC Gene and Insights into the DNA-Binding Specificity of the Zinc-Sensing Metalloregulator Zur

(2008) S. E. Gabriel et al.   JOURNAL OF BACTERIOLOGY

Glutathione and Transition-Metal Homeostasis in Escherichia coli

(2008) K. Helbig et al.   JOURNAL OF BACTERIOLOGY

Structure of the Two Transmembrane Cu+Transport Sites of the Cu+-ATPases

(2008) Manuel González-Guerrero et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

How do bacterial cells ensure that metalloproteins get the correct metal?

(2008) Kevin J. Waldron et al.   NATURE REVIEWS MICROBIOLOGY

Metal Chelation and Inhibition of Bacterial Growth in Tissue Abscesses

(2008) Brian D. Corbin et al.   SCIENCE

Zinc is a key factor in controlling alternation of two types of L31 protein in the Bacillus subtilis ribosome

(2004) Hideaki Nanamiya et al.   MOLECULAR MICROBIOLOGY