Structural Elements in the Transmembrane and Cytoplasmic Domains of the Metal Transporter SLC30A10 Are Required for Its Manganese Efflux Activity

Functional Determinants of Metal Ion Transport and Selectivity in Paralogous Cation Diffusion Facilitator Transporters CzcD and MntE in Streptococcus pneumoniae

(2016) Julia E. Martin et al.   JOURNAL OF BACTERIOLOGY

Direct Comparison of Manganese Detoxification/Efflux Proteins and Molecular Characterization of ZnT10 Protein as a Manganese Transporter

(2016) Yukina Nishito et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cation Diffusion Facilitator family: Structure and function

(2015) Olga Kolaj-Robin et al.   FEBS LETTERS

The Physiological, Biochemical, and Molecular Roles of Zinc Transporters in Zinc Homeostasis and Metabolism

(2015) Taiho Kambe et al.   PHYSIOLOGICAL REVIEWS

Common Polymorphisms in the Solute Carrier SLC30A10 are Associated With Blood Manganese and Neurological Function

(2015) Karin Wahlberg et al.   TOXICOLOGICAL SCIENCES

A Conserved Structural Motif Mediates Retrograde Trafficking of Shiga Toxin Types 1 and 2

(2015) Andrey S. Selyunin et al.   TRAFFIC

Pathology of inherited manganese transporter deficiency

(2014) Mirna Lechpammer et al.   ANNALS OF NEUROLOGY

SLC30A10 Is a Cell Surface-Localized Manganese Efflux Transporter, and Parkinsonism-Causing Mutations Block Its Intracellular Trafficking and Efflux Activity

(2014) D. Leyva-Illades et al.   JOURNAL OF NEUROSCIENCE

ZnT-1 extrudes zinc from mammalian cells functioning as a Zn2+/H+ exchanger

(2014) Eden Shusterman et al.   Metallomics

The SLC30 family of zinc transporters – A review of current understanding of their biological and pathophysiological roles

(2013) Liping Huang et al.   MOLECULAR ASPECTS OF MEDICINE

Cooperative Functions of ZnT1, Metallothionein and ZnT4 in the Cytoplasm Are Required for Full Activation of TNAP in the Early Secretory Pathway

(2013) Shigeyuki Fujimoto et al.   PLoS One

Inward-facing conformation of the zinc transporter YiiP revealed by cryoelectron microscopy

(2013) N. Coudray et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutations in SLC30A10 Cause Parkinsonism and Dystonia with Hypermanganesemia, Polycythemia, and Chronic Liver Disease

(2012) Marialuisa Quadri et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Syndrome of Hepatic Cirrhosis, Dystonia, Polycythemia, and Hypermanganesemia Caused by Mutations in SLC30A10 , a Manganese Transporter in Man

(2012) Karin Tuschl et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Parkinsonism in cirrhosis: pathogenesis and current therapeutic options

(2012) Roger F. Butterworth   METABOLIC BRAIN DISEASE

Tremor, olfactory and motor changes in Italian adolescents exposed to historical ferro-manganese emission

(2012) Roberto G. Lucchini et al.   NEUROTOXICOLOGY

Histidine pairing at the metal transport site of mammalian ZnT transporters controls Zn2+ over Cd2+ selectivity

(2012) E. Hoch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Manganese Blocks Intracellular Trafficking of Shiga Toxin and Protects Against Shiga Toxicosis

(2012) S. Mukhopadhyay et al.   SCIENCE

Golgi phosphoprotein 4 (GPP130) is a sensitive and selective cellular target of manganese exposure

(2012) Melisa Masuda et al.   SYNAPSE

A practical guide to evaluating colocalization in biological microscopy

(2011) Kenneth W. Dunn et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Tissue Nonspecific Alkaline Phosphatase Is Activated via a Two-step Mechanism by Zinc Transport Complexes in the Early Secretory Pathway

(2011) Ayako Fukunaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Manganese-induced Trafficking and Turnover of the cis-Golgi Glycoprotein GPP130

(2010) Somshuvra Mukhopadhyay et al.   MOLECULAR BIOLOGY OF THE CELL

Identification of a gain-of-function mutation in a Golgi P-type ATPase that enhances Mn2+ efflux and protects against toxicity

(2010) S. Mukhopadhyay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of the Zn2+Binding Site and Mode of Operation of a Mammalian Zn2+Transporter

(2009) Ehud Ohana et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Manganese exposure is cytotoxic and alters dopaminergic and GABAergic neurons within the basal ganglia

(2009) Gregg D. Stanwood et al.   JOURNAL OF NEUROCHEMISTRY

Protein structure prediction on the Web: a case study using the Phyre server

(2009) Lawrence A Kelley et al.   Nature Protocols

Structural basis for autoregulation of the zinc transporter YiiP

(2009) Min Lu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Manganese and its Role in Parkinson’s Disease: From Transport to Neuropathology

(2009) Michael Aschner et al.   NEUROMOLECULAR MEDICINE

Oxidative damage and neurodegeneration in manganese-induced neurotoxicity

(2009) Dejan Milatovic et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Metals in proteins: correlation between the metal-ion type, coordination number and the amino-acid residues involved in the coordination

(2008) Ivan Dokmanić et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

A Single Amino Acid Change in the Yeast Vacuolar Metal Transporters Zrc1 and Cot1 Alters Their Substrate Specificity

(2008) Huilan Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hepatic cirrhosis, dystonia, polycythaemia and hypermanganesaemia—A new metabolic disorder

(2008) Karin Tuschl et al.   JOURNAL OF INHERITED METABOLIC DISEASE