Direct Comparison of Manganese Detoxification/Efflux Proteins and Molecular Characterization of ZnT10 Protein as a Manganese Transporter

Differential Targeting of SLC30A10/ZnT10 Heterodimers to Endolysosomal Compartments Modulates EGF-Induced MEK/ERK1/2 Activity

(2016) Yitong Zhao et al.   TRAFFIC

Soybean extracts increase cell surface ZIP4 abundance and cellular zinc levels: a potential novel strategy to enhance zinc absorption by ZIP4 targeting

(2015) A. Hashimoto et al.   BIOCHEMICAL JOURNAL

Genome-wide association study of toxic metals and trace elements reveals novel associations

(2015) Esther Ng et al.   HUMAN MOLECULAR GENETICS

Manganese homeostasis in the nervous system

(2015) Pan Chen et al.   JOURNAL OF NEUROCHEMISTRY

The Physiological, Biochemical, and Molecular Roles of Zinc Transporters in Zinc Homeostasis and Metabolism

(2015) Taiho Kambe et al.   PHYSIOLOGICAL REVIEWS

Parkinson's disease-associated human ATP13A2 (PARK9) deficiency causes zinc dyshomeostasis and mitochondrial dysfunction

(2014) Jin-Sung Park et al.   HUMAN MOLECULAR GENETICS

SLC30A10 Is a Cell Surface-Localized Manganese Efflux Transporter, and Parkinsonism-Causing Mutations Block Its Intracellular Trafficking and Efflux Activity

(2014) D. Leyva-Illades et al.   JOURNAL OF NEUROSCIENCE

ZnT-1 extrudes zinc from mammalian cells functioning as a Zn2+/H+ exchanger

(2014) Eden Shusterman et al.   Metallomics

Golgi Localized Barley MTP8 Proteins Facilitate Mn Transport

(2014) Pai Pedas et al.   PLoS One

Zn2+ dyshomeostasis caused by loss of ATP13A2/PARK9 leads to lysosomal dysfunction and alpha-synuclein accumulation

(2013) Taiji Tsunemi et al.   HUMAN MOLECULAR GENETICS

Suppression of ZIP8 expression is a common feature of cadmium-resistant and manganese-resistant RBL-2H3 cells

(2013) Hitomi Fujishiro et al.   Metallomics

Compound Heterozygous Mutations in SLC30A2/ZnT2 Results in Low Milk Zinc Concentrations: A Novel Mechanism for Zinc Deficiency in a Breast-Fed Infant

(2013) Naoya Itsumura et al.   PLoS One

Cooperative Functions of ZnT1, Metallothionein and ZnT4 in the Cytoplasm Are Required for Full Activation of TNAP in the Early Secretory Pathway

(2013) Shigeyuki Fujimoto et al.   PLoS One

Inward-facing conformation of the zinc transporter YiiP revealed by cryoelectron microscopy

(2013) N. Coudray et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutations in SLC30A10 Cause Parkinsonism and Dystonia with Hypermanganesemia, Polycythemia, and Chronic Liver Disease

(2012) Marialuisa Quadri et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Syndrome of Hepatic Cirrhosis, Dystonia, Polycythemia, and Hypermanganesemia Caused by Mutations in SLC30A10 , a Manganese Transporter in Man

(2012) Karin Tuschl et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Physiologic implications of metal-ion transport by ZIP14 and ZIP8

(2012) Supak Jenkitkasemwong et al.   BIOMETALS

Efflux function, tissue-specific expression and intracellular trafficking of the Zn transporter ZnT10 indicate roles in adult Zn homeostasis

(2012) Helen J. Bosomworth et al.   Metallomics

Roles of ZIP8, ZIP14, and DMT1 in transport of cadmium and manganese in mouse kidney proximal tubule cells

(2012) Hitomi Fujishiro et al.   Metallomics

Angiotensin II Requires Zinc and Downregulation of the Zinc Transporters ZnT3 and ZnT10 to Induce Senescence of Vascular Smooth Muscle Cells

(2012) Nikolay Patrushev et al.   PLoS One

The Role of the Parkinson's Disease Gene PARK9 in Essential Cellular Pathways and the Manganese Homeostasis Network in Yeast

(2012) Alessandra Chesi et al.   PLoS One

Histidine pairing at the metal transport site of mammalian ZnT transporters controls Zn2+ over Cd2+ selectivity

(2012) E. Hoch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The iron transporter ferroportin can also function as a manganese exporter

(2011) Michael S. Madejczyk et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Structure and evolution of the plant cation diffusion facilitator family of ion transporters

(2011) Jeffery L Gustin et al.   BMC EVOLUTIONARY BIOLOGY

Regulation of Intracellular Manganese Homeostasis by Kufor-Rakeb Syndrome-associated ATP13A2 Protein

(2011) Jieqiong Tan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tissue Nonspecific Alkaline Phosphatase Is Activated via a Two-step Mechanism by Zinc Transport Complexes in the Early Secretory Pathway

(2011) Ayako Fukunaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Patterns of levels of biological metals in CSF differ among neurodegenerative diseases

(2011) Isao Hozumi et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Role of manganese in neurodegenerative diseases

(2011) Aaron B. Bowman et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Molecular and genetic features of zinc transporters in physiology and pathogenesis

(2011) Toshiyuki Fukada et al.   Metallomics

Biological effects of mutant ceruloplasmin on hepcidin-mediated internalization of ferroportin

(2010) Satoshi Kono et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Vesicular distribution of Secretory Pathway Ca2+-ATPase isoform 1 and a role in manganese detoxification in liver-derived polarized cells

(2010) Sharon Leitch et al.   BIOMETALS

Cytosolic metal handling in plants: determinants for zinc specificity in metal transporters and metallothioneins

(2010) Claudia A. Blindauer et al.   Metallomics

Identification of a gain-of-function mutation in a Golgi P-type ATPase that enhances Mn2+ efflux and protects against toxicity

(2010) S. Mukhopadhyay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SLC39A9 (ZIP9) Regulates Zinc Homeostasis in the Secretory Pathway: Characterization of the ZIP Subfamily I Protein in Vertebrate Cells

(2009) Wataru MATSUURA et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Manganese Homeostasis inSaccharomyces cerevisiae

(2009) Amit R. Reddi et al.   CHEMICAL REVIEWS

Identification of the Zn2+Binding Site and Mode of Operation of a Mammalian Zn2+Transporter

(2009) Ehud Ohana et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ferroportin is a manganese-responsive protein that decreases manganese cytotoxicity and accumulation

(2009) Zhaobao Yin et al.   JOURNAL OF NEUROCHEMISTRY

α-Synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity

(2009) Aaron D Gitler et al.   NATURE GENETICS

Structural basis for autoregulation of the zinc transporter YiiP

(2009) Min Lu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

From Manganism to Manganese-Induced Parkinsonism: A Conceptual Model Based on the Evolution of Exposure

(2009) Roberto G. Lucchini et al.   NEUROMOLECULAR MEDICINE

Manganese and its Role in Parkinson’s Disease: From Transport to Neuropathology

(2009) Michael Aschner et al.   NEUROMOLECULAR MEDICINE

Manganese and birth outcome

(2009) Richard J Wood   NUTRITION REVIEWS

Deletion of a Histidine-rich Loop of AtMTP1, a Vacuolar Zn2+/H+Antiporter ofArabidopsis thaliana, Stimulates the Transport Activity

(2008) Miki Kawachi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Manganese transport in eukaryotes: The role of DMT1

(2008) Catherine Au et al.   NEUROTOXICOLOGY