C4b-binding Protein Protects β-Cells from Islet Amyloid Polypeptide-induced Cytotoxicity

Molecular Structure, Membrane Interactions, and Toxicity of the Islet Amyloid Polypeptide in Type 2 Diabetes Mellitus

(2016) Lucie Caillon et al.   Journal of Diabetes Research

Heparan Sulfate Proteoglycans Are Important for Islet Amyloid Formation and Islet Amyloid Polypeptide-induced Apoptosis

(2015) Marie E. Oskarsson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Novel Non-Synonymous Polymorphism (p.Arg240His) in C4b-Binding Protein Is Associated with Atypical Hemolytic Uremic Syndrome and Leads to Impaired Alternative Pathway Cofactor Activity

(2014) Anna M. Blom et al.   JOURNAL OF IMMUNOLOGY

Analysis of genes coding for CD46, CD55, and C4b-binding protein in patients with idiopathic, recurrent, spontaneous pregnancy loss

(2013) Frida C. Mohlin et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The  7 0 Isoform of the Complement Regulator C4b-Binding Protein Induces a Semimature, Anti-Inflammatory State in Dendritic Cells

(2013) R. Olivar et al.   JOURNAL OF IMMUNOLOGY

Staphylococcal Proteases Aid in Evasion of the Human Complement System

(2013) Monika Jusko et al.   Journal of Innate Immunity

Islet Amyloid Polypeptide Triggers Limited Complement Activation and Binds Complement Inhibitor C4b-binding Protein, Which Enhances Fibril Formation

(2012) Jonatan Sjölander et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Analysis of Beta-Cell Gene Expression Reveals Inflammatory Signaling and Evidence of Dedifferentiation following Human Islet Isolation and Culture

(2012) Sarita Negi et al.   PLoS One

β-Cell Loss and β-Cell Apoptosis in Human Type 2 Diabetes Are Related to Islet Amyloid Deposition

(2011) Catherine A. Jurgens et al.   AMERICAN JOURNAL OF PATHOLOGY

Concentration-dependent transitions govern the subcellular localization of islet amyloid polypeptide

(2011) Mazin Magzoub et al.   FASEB JOURNAL

Clustering and Internalization of Toxic Amylin Oligomers in Pancreatic Cells Require Plasma Membrane Cholesterol

(2011) Saurabh Trikha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Complement: a key system for immune surveillance and homeostasis

(2010) Daniel Ricklin et al.   NATURE IMMUNOLOGY

Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

(2010) Seth L Masters et al.   NATURE IMMUNOLOGY

Complement evasion strategies of pathogens—Acquisition of inhibitors and beyond

(2009) Anna M. Blom et al.   MOLECULAR IMMUNOLOGY

Islet Amyloid in Type 2 Diabetes, and the Toxic Oligomer Hypothesis

(2008) Leena Haataja et al.   ENDOCRINE REVIEWS

Cellular uptake of C4b-binding protein is mediated by heparan sulfate proteoglycans and CD91/LDL receptor-related protein

(2008) Patricia P. Spijkers et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Real-Time Monitoring of Apoptosis by Caspase-3-Like Protease Induced FRET Reduction Triggered by Amyloid Aggregation

(2008) Johan F. Paulsson et al.   Experimental Diabetes Research

C4b-binding protein in Alzheimer's disease: Binding to Aβ1–42 and to dead cells

(2008) Leendert. A. Trouw et al.   MOLECULAR IMMUNOLOGY

Native, amyloid fibrils and β-oligomers of the C-terminal domain of human prion protein display differential activation of complement and bind C1q, factor H and C4b-binding protein directly

(2008) Andreas P. Sjöberg et al.   MOLECULAR IMMUNOLOGY

Membrane damage by human islet amyloid polypeptide through fibril growth at the membrane

(2008) M. F. M. Engel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA