Structure of the Shroom-Rho Kinase Complex Reveals a Binding Interface with Monomeric Shroom That Regulates Cell Morphology and Stimulates Kinase Activity

Targeted inhibition of the Shroom3–Rho kinase protein–protein interaction circumvents Nogo66 to promote axon outgrowth

(2015) Heather M Dickson et al.   BMC NEUROSCIENCE

Actin Out: Regulation of the Synaptic Cytoskeleton

(2015) Erin F. Spence et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Kinase-interacting substrate screening is a novel method to identify kinase substrates

(2015) Mutsuki Amano et al.   JOURNAL OF CELL BIOLOGY

WASp-dependent actin cytoskeleton stability at the dendritic cell immunological synapse is required for extensive, functional T cell contacts

(2015) Dessislava Malinova et al.   JOURNAL OF LEUKOCYTE BIOLOGY

A molecular ruler regulates cytoskeletal remodelling by the Rho kinases

(2015) Linda Truebestein et al.   Nature Communications

The interaction between Shroom3 and Rho-kinase is required for neural tube morphogenesis in mice

(2014) D. Das et al.   Biology Open

Associations between the Rho kinase-1 catalytic and PH domain regulatory unit

(2013) John W. Craft et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

Structure of a Highly Conserved Domain of Rock1 Required for Shroom-Mediated Regulation of Cell Morphology

(2013) Swarna Mohan et al.   PLoS One

Structure of Shroom domain 2 reveals a three-segmented coiled-coil required for dimerization, Rock binding, and apical constriction

(2012) Swarna Mohan et al.   MOLECULAR BIOLOGY OF THE CELL

Improving FRET dynamic range with bright green and red fluorescent proteins

(2012) Amy J Lam et al.   NATURE METHODS

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Linking Crystallographic Model and Data Quality

(2012) P. A. Karplus et al.   SCIENCE

Cell dynamics in fetal intestinal epithelium: implications for intestinal growth and morphogenesis

(2011) A. S. Grosse et al.   DEVELOPMENT

Shroom3 and a Pitx2-N-cadherin pathway function cooperatively to generate asymmetric cell shape changes during gut morphogenesis

(2011) Timothy F. Plageman et al.   DEVELOPMENTAL BIOLOGY

Shroom2 regulates contractility to control endothelial morphogenesis

(2011) Matthew J. Farber et al.   MOLECULAR BIOLOGY OF THE CELL

Crystal Structure of a Coiled-Coil Domain from Human ROCK I

(2011) Daqi Tu et al.   PLoS One

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Pax6-dependent Shroom3 expression regulates apical constriction during lens placode invagination

(2010) T. F. Plageman et al.   DEVELOPMENT

Specific isoforms of drosophila shroom define spatial requirements for the induction of apical constriction

(2010) Cory Bolinger et al.   DEVELOPMENTAL DYNAMICS

Sonic hedgehog induces angiogenesis via Rho kinase-dependent signaling in endothelial cells

(2010) Marie-Ange Renault et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The cytoskeleton and cancer

(2009) Alan Hall   CANCER AND METASTASIS REVIEWS

hShroom1 links a membrane bound protein to the actin cytoskeleton

(2009) D. E. Dye et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Shroom3-mediated recruitment of Rho kinases to the apical cell junctions regulates epithelial and neuroepithelial planar remodeling

(2008) T. Nishimura et al.   DEVELOPMENT