Structure of Shroom domain 2 reveals a three-segmented coiled-coil required for dimerization, Rock binding, and apical constriction

Shroom3 and a Pitx2-N-cadherin pathway function cooperatively to generate asymmetric cell shape changes during gut morphogenesis

(2011) Timothy F. Plageman et al.   DEVELOPMENTAL BIOLOGY

ROCK1 as a potential therapeutic target in osteosarcoma

(2011) Xianzhe Liu et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Shroom2 regulates contractility to control endothelial morphogenesis

(2011) Matthew J. Farber et al.   MOLECULAR BIOLOGY OF THE CELL

Crystal Structure of a Coiled-Coil Domain from Human ROCK I

(2011) Daqi Tu et al.   PLoS One

Rho and Rho-Kinase Activity in Adipocytes Contributes to a Vicious Cycle in Obesity That May Involve Mechanical Stretch

(2011) Y. Hara et al.   Science Signaling

Validation of crystallographic models containing TLS or other descriptions of anisotropy

(2010) Frank Zucker et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Aberrant ROCK activation promotes the development of type I diabetes in NOD mice

(2010) Partha S. Biswas et al.   CELLULAR IMMUNOLOGY

Pax6-dependent Shroom3 expression regulates apical constriction during lens placode invagination

(2010) T. F. Plageman et al.   DEVELOPMENT

Direct activation of Shroom3 transcription by Pitx proteins drives epithelial morphogenesis in the developing gut

(2010) M.-I Chung et al.   DEVELOPMENT

Specific isoforms of drosophila shroom define spatial requirements for the induction of apical constriction

(2010) Cory Bolinger et al.   DEVELOPMENTAL DYNAMICS

Rho-kinase inhibition: a novel therapeutic target for the treatment of cardiovascular diseases

(2010) Ming Dong et al.   DRUG DISCOVERY TODAY

Key role of the RhoA/Rho kinase system in pulmonary hypertension

(2010) Michelle J. Connolly et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

The shroom family proteins play broad roles in the morphogenesis of thickened epithelial sheets

(2009) Chanjae Lee et al.   DEVELOPMENTAL DYNAMICS

Multiple loci associated with indices of renal function and chronic kidney disease

(2009) Anna Köttgen et al.   NATURE GENETICS

Shroom3-mediated recruitment of Rho kinases to the apical cell junctions regulates epithelial and neuroepithelial planar remodeling

(2008) T. Nishimura et al.   DEVELOPMENT

Mechanism of multi-site phosphorylation from a ROCK-I:RhoE complex structure

(2008) David Komander et al.   EMBO JOURNAL

Structure Basis and Unconventional Lipid Membrane Binding Properties of the PH-C1 Tandem of Rho Kinases

(2008) Wenyu Wen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Scaffold Protein POSH Regulates Axon Outgrowth

(2008) Jennifer Taylor et al.   MOLECULAR BIOLOGY OF THE CELL