SLX4-SLX1 Protein-independent Down-regulation of MUS81-EME1 Protein by HIV-1 Viral Protein R (Vpr)

CRL4VprBP E3 Ligase Promotes Monoubiquitylation and Chromatin Binding of TET Dioxygenases

(2015) Tadashi Nakagawa et al.   MOLECULAR CELL

Understanding the molecular manipulation of DCAF1 by the lentiviral accessory proteins Vpr and Vpx

(2015) Patrick A. Cassiday et al.   VIROLOGY

Determinants for degradation of SAMHD1, Mus81 and induction of G 2 arrest in HIV-1 Vpr and SIVagm Vpr

(2015) Ana Beatriz DePaula-Silva et al.   VIROLOGY

Premature Activation of the SLX4 Complex by Vpr Promotes G2/M Arrest and Escape from Innate Immune Sensing

(2014) Nadine Laguette et al.   CELL

Identification and characterization of MUS81 point mutations that abolish interaction with the SLX4 scaffold protein

(2014) Nidhi Nair et al.   DNA REPAIR

Holliday junction resolution: Regulation in space and time

(2014) Joao Matos et al.   DNA REPAIR

G2/M Cell Cycle Arrest Correlates with Primate Lentiviral Vpr Interaction with the SLX4 Complex

(2014) Gregory Berger et al.   JOURNAL OF VIROLOGY

Human MUS81-EME2 can cleave a variety of DNA structures including intact Holliday junction and nicked duplex

(2014) Tamir Amangyeld et al.   NUCLEIC ACIDS RESEARCH

Deciphering key features in protein structures with the new ENDscript server

(2014) Xavier Robert et al.   NUCLEIC ACIDS RESEARCH

How SLX4 cuts through the mystery of HIV-1 Vpr-mediated cell cycle arrest

(2014) Marie-Lise Blondot et al.   Retrovirology

MUS81-EME2 Promotes Replication Fork Restart

(2014) Alessandra Pepe et al.   Cell Reports

VprBP (DCAF1): a promiscuous substrate recognition subunit that incorporates into both RING-family CRL4 and HECT-family EDD/UBR5 E3 ubiquitin ligases

(2013) Tadashi Nakagawa et al.   BMC MOLECULAR BIOLOGY

HIV-2 and SIVmac Accessory Virulence Factor Vpx Down-regulates SAMHD1 Enzyme Catalysis Prior to Proteasome-dependent Degradation

(2013) Maria DeLucia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cooperative Control of Holliday Junction Resolution and DNA Repair by the SLX1 and MUS81-EME1 Nucleases

(2013) Dennis Castor et al.   MOLECULAR CELL

Coordinated Actions of SLX1-SLX4 and MUS81-EME1 for Holliday Junction Resolution in Human Cells

(2013) Haley D.M. Wyatt et al.   MOLECULAR CELL

VprBP Has Intrinsic Kinase Activity Targeting Histone H2A and Represses Gene Transcription

(2013) Kyunghwan Kim et al.   MOLECULAR CELL

Substrate specificity of the MUS81-EME2 structure selective endonuclease

(2013) A. Pepe et al.   NUCLEIC ACIDS RESEARCH

Analysis Tool Web Services from the EMBL-EBI

(2013) Hamish McWilliam et al.   NUCLEIC ACIDS RESEARCH

The Ability of Primate Lentiviruses to Degrade the Monocyte Restriction Factor SAMHD1 Preceded the Birth of the Viral Accessory Protein Vpx

(2012) Efrem S. Lim et al.   Cell Host & Microbe

Lentivirus Vpr and Vpx accessory proteins usurp the cullin4–DDB1 (DCAF1) E3 ubiquitin ligase

(2012) Bizhan Romani et al.   Current Opinion in Virology

An interview with Dr. Catherine Transy and Dr. Florence Margottin-Goguet on their highly cited paper published inCell Cycle

(2011) Catherine Transy   CELL CYCLE

Vpr-Binding Protein Antagonizes p53-Mediated Transcription via Direct Interaction with H3 Tail

(2011) K. Kim et al.   MOLECULAR AND CELLULAR BIOLOGY

HIV-1 Accessory Protein Vpr: Relevance in the pathogenesis of HIV and potential for therapeutic intervention

(2011) Michael Kogan et al.   Retrovirology

Immune Evasion and Counteraction of Restriction Factors by HIV-1 and Other Primate Lentiviruses

(2010) Frank Kirchhoff   Cell Host & Microbe

HIV-1 Vpr Induces the K48-Linked Polyubiquitination and Proteasomal Degradation of Target Cellular Proteins To Activate ATR and Promote G2 Arrest

(2010) J.-P. Belzile et al.   JOURNAL OF VIROLOGY

Limelight on two HIV/SIV accessory proteins in macrophage infection: Is Vpx overshadowing Vpr?

(2010) Diana Ayinde et al.   Retrovirology

Formation of Mobile Chromatin-Associated Nuclear Foci Containing HIV-1 Vpr and VPRBP Is Critical for the Induction of G2 Cell Cycle Arrest

(2010) Jean-Philippe Belzile et al.   PLoS Pathogens

Human SLX4 Is a Holliday Junction Resolvase Subunit that Binds Multiple DNA Repair/Recombination Endonucleases

(2009) Samira Fekairi et al.   CELL

Virion-Associated Vpr of Human Immunodeficiency Virus Type 1 Triggers Activation of Apoptotic Events and Enhances Fas-Induced Apoptosis in Human T Cells

(2009) H. Arokium et al.   JOURNAL OF VIROLOGY

Characterization of the Molecular Determinants of Primary HIV-1 Vpr Proteins: Impact of the Q65R and R77Q Substitutions on Vpr Functions

(2009) Guillaume Jacquot et al.   PLoS One

Structural and Functional Relationships of the XPF/MUS81 Family of Proteins

(2008) Alberto Ciccia et al.   Annual Review of Biochemistry

Assembly with the Cul4A-DDB1DCAF1Ubiquitin Ligase Protects HIV-1 Vpr from Proteasomal Degradation

(2008) Erwann Le Rouzic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Immunodeficiency Virus Type 1 Vpr-Binding Protein VprBP, a WD40 Protein Associated with the DDB1-CUL4 E3 Ubiquitin Ligase, Is Essential for DNA Replication and Embryonic Development

(2008) C. M. McCall et al.   MOLECULAR AND CELLULAR BIOLOGY