Blunting Autoantigen-induced FOXO3a Protein Phosphorylation and Degradation Is a Novel Pathway of Glucocorticoids for the Treatment of Systemic Lupus Erythematosus

TIPE2 Alleviates Systemic Lupus Erythematosus Through Regulating Macrophage Polarization

(2016) Feng Li et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Accelerated vascular disease in systemic lupus erythematosus: Role of macrophage

(2015) Mohammed M. Al Gadban et al.   CLINICAL IMMUNOLOGY

FOXO3: A Major Gene for Human Longevity - A Mini-Review

(2015) Brian J. Morris et al.   GERONTOLOGY

FOXO3a and Posttranslational Modifications Mediate Glucocorticoid Sensitivity in B-ALL

(2015) F. Consolaro et al.   MOLECULAR CANCER RESEARCH

Genetics and pathogenesis of systemic lupus erythematosus and lupus nephritis

(2015) Chandra Mohan et al.   Nature Reviews Nephrology

HMGB1 Promotes Systemic Lupus Erythematosus by Enhancing Macrophage Inflammatory Response

(2015) Mudan Lu et al.   Journal of Immunology Research

Interleukin-6 promotes systemic lupus erythematosus progression with Treg suppression approach in a murine systemic lupus erythematosus model

(2014) Xiaoli Mao et al.   CLINICAL RHEUMATOLOGY

MicroRNA-155 Is Involved in the Pathogenesis of Ulcerative Colitis by Targeting FOXO3a

(2014) Min Min et al.   INFLAMMATORY BOWEL DISEASES

Inhibition of PI3Kδ Reduces Kidney Infiltration by Macrophages and Ameliorates Systemic Lupus in the Mouse

(2014) Abel Suárez-Fueyo et al.   JOURNAL OF IMMUNOLOGY

The pathogenesis and diagnosis of systemic lupus erythematosus: still not resolved

(2014) Ole Petter Rekvig et al.   Seminars in Immunopathology

FOXO transcription factors: key regulators of cellular quality control

(2014) Ashley E. Webb et al.   TRENDS IN BIOCHEMICAL SCIENCES

Human SNP Links Differential Outcomes in Inflammatory and Infectious Disease to a FOXO3-Regulated Pathway

(2013) James C. Lee et al.   CELL

DNA-dependent Activator of Interferon-regulatory Factors (DAI) Promotes Lupus Nephritis by Activating the Calcium Pathway

(2013) Weijuan Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of Histone Deacetylase Activity Suppresses IFN-  Induction of Tripartite Motif 22 via CHIP-Mediated Proteasomal Degradation of IRF-1

(2013) B. Gao et al.   JOURNAL OF IMMUNOLOGY

FOXOs: signalling integrators for homeostasis maintenance

(2013) Astrid Eijkelenboom et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Granulin Exacerbates Lupus Nephritis via Enhancing Macrophage M2b Polarization

(2013) Xi Chen et al.   PLoS One

The use of glucocorticoids in Systemic Lupus Erythematosus. After 60years still more an art than science

(2012) Remco K.M.A.C. Luijten et al.   AUTOIMMUNITY REVIEWS

FOXO1 Increases CCL20 to Promote NF-κB-Dependent Lymphocyte Chemotaxis

(2012) Hongming Miao et al.   MOLECULAR ENDOCRINOLOGY

A20 (TNFAIP3) Alleviates CVB3-Induced Myocarditis via Inhibiting NF-κB Signaling

(2012) Jun Gui et al.   PLoS One

Glucocorticoid use and abuse in SLE

(2012) G. Ruiz-Irastorza et al.   RHEUMATOLOGY

Regulation of FOXO protein stability via ubiquitination and proteasome degradation

(2011) Haojie Huang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Macrophage Differentiation and Polarization via Phosphatidylinositol 3-Kinase/Akt-ERK Signaling Pathway Conferred by Serum Amyloid P Component

(2011) W. Zhang et al.   JOURNAL OF IMMUNOLOGY

Modulation of FoxO1 phosphorylation/acetylation by baicalin during aging

(2011) Dae Hyun Kim et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Blockade of TLR9 signaling in B cells impaired anti-dsDNA antibody production in mice induced by activated syngenic lymphocyte-derived DNA immunization

(2011) Min Chen et al.   MOLECULAR IMMUNOLOGY

Systemic Lupus Erythematosus

(2011) George C. Tsokos   NEW ENGLAND JOURNAL OF MEDICINE

Highly Specialized Role of Forkhead Box O Transcription Factors in the Immune System

(2010) Anne S. Dejean et al.   ANTIOXIDANTS & REDOX SIGNALING

Expanding role of ubiquitination in NF-κB signaling

(2010) Siqi Liu et al.   CELL RESEARCH

Urinary Biomarkers in Lupus Nephritis

(2010) Joyce Reyes-Thomas et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

A 5' Extended IFN-Stimulating Response Element Is Crucial for IFN- -Induced Tripartite Motif 22 Expression via Interaction with IFN Regulatory Factor-1

(2010) B. Gao et al.   JOURNAL OF IMMUNOLOGY

Blockade of Notch1 Signaling Alleviates Murine Lupus via Blunting Macrophage Activation and M2b Polarization

(2010) W. Zhang et al.   JOURNAL OF IMMUNOLOGY

Mechanisms and resistance in glucocorticoid control of inflammation

(2010) Peter J. Barnes   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

A New Fork for Clinical Application: Targeting Forkhead Transcription Factors in Cancer

(2009) J.-Y. Yang et al.   CLINICAL CANCER RESEARCH

FoxO4 Inhibits NF-κB and Protects Mice Against Colonic Injury and Inflammation

(2009) Wen Zhou et al.   GASTROENTEROLOGY

Tumor suppressor FOXO3 participates in the regulation of intestinal inflammation

(2009) Lobke Snoeks et al.   LABORATORY INVESTIGATION

Glucocorticoid resistance in inflammatory diseases

(2009) Peter J Barnes et al.   LANCET

Glucocorticoid-induced apoptosis requires FOXO3A activity

(2008) Jiexian Ma et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The FoxO code

(2008) D R Calnan et al.   ONCOGENE

Genomic and nongenomic effects of glucocorticoids

(2008) Cindy Stahn et al.   Nature clinical practice. Rheumatology