Lipid-tuned Zinc Transport Activity of Human ZnT8 Protein Correlates with Risk for Type-2 Diabetes

Zinc and diabetes

(2016) Pauline Chabosseau et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Rare and Common Genetic Events in Type 2 Diabetes: What Should Biologists Know?

(2015) Amélie Bonnefond et al.   Cell Metabolism

Characterization of Phospholipids in Insulin Secretory Granules and Mitochondria in Pancreatic Beta Cells and Their Changes with Glucose Stimulation

(2015) Michael J. MacDonald et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SLC30A8 mutations in type 2 diabetes

(2014) Guy A. Rutter et al.   DIABETOLOGIA

Visualizing the kinetic power stroke that drives proton-coupled zinc(ii) transport

(2014) Sayan Gupta et al.   NATURE

Loss-of-function mutations in SLC30A8 protect against type 2 diabetes

(2014) Jason Flannick et al.   NATURE GENETICS

Zinc transporter 8 (ZnT8) and β cell function

(2014) Howard W. Davidson et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Cholesterol Biosynthesis Pathway Intermediates and Inhibitors Regulate Glucose-Stimulated Insulin Secretion and Secretory Granule Formation in Pancreatic β-Cells

(2010) Miho Tsuchiya et al.   ENDOCRINOLOGY

A low-risk ZnT-8 allele (W325) for post-transplantation diabetes mellitus is protective against cyclosporin A-induced impairment of insulin secretion

(2010) I Kim et al.   PHARMACOGENOMICS JOURNAL

Lipid Rafts As a Membrane-Organizing Principle

(2010) D. Lingwood et al.   SCIENCE

Insulin Storage and Glucose Homeostasis in Mice Null for the Granule Zinc Transporter ZnT8 and Studies of the Type 2 Diabetes-Associated Variants

(2009) T. J. Nicolson et al.   DIABETES

Structural basis for autoregulation of the zinc transporter YiiP

(2009) Min Lu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Insulin crystallization depends on zinc transporter ZnT8 expression, but is not required for normal glucose homeostasis in mice

(2009) K. Lemaire et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA