Regulation of Receptor for Advanced Glycation End Products (RAGE) Ectodomain Shedding and Its Role in Cell Function

Twenty years of theMEROPSdatabase of proteolytic enzymes, their substrates and inhibitors

(2015) Neil D. Rawlings et al.   NUCLEIC ACIDS RESEARCH

LC–MS Based Cleavage Site Profiling of the Proteases ADAM10 and ADAM17 Using Proteome-Derived Peptide Libraries

(2014) Joanna Tucher et al.   JOURNAL OF PROTEOME RESEARCH

The Receptor for Advanced Glycation End-Products (RAGE) Is Only Present in Mammals, and Belongs to a Family of Cell Adhesion Molecules (CAMs)

(2014) Luca Sessa et al.   PLoS One

Clearance Kinetics and Matrix Binding Partners of the Receptor for Advanced Glycation End Products

(2014) Pavle S. Milutinovic et al.   PLoS One

Effect of insulin on the soluble receptor for advanced glycation end products (RAGE)

(2013) J. K. Y. Lam et al.   DIABETIC MEDICINE

Common Interactions between S100A4 and S100A9 Defined by a Novel Chemical Probe

(2013) Per Björk et al.   PLoS One

Alternative Splicing of the RAGE Cytoplasmic Domain Regulates Cell Signaling and Function

(2013) Joel Jules et al.   PLoS One

JAM-A protects from thrombosis by suppressing integrin  IIb 3-dependent outside-in signaling in platelets

(2012) M. U. Naik et al.   BLOOD

RAGE binds C1q and enhances C1q-mediated phagocytosis

(2012) Wanchao Ma et al.   CELLULAR IMMUNOLOGY

S100P-Derived RAGE Antagonistic Peptide Reduces Tumor Growth and Metastasis

(2012) T. Arumugam et al.   CLINICAL CANCER RESEARCH

A multimodal RAGE-specific inhibitor reduces amyloid β–mediated brain disorder in a mouse model of Alzheimer disease

(2012) Rashid Deane et al.   JOURNAL OF CLINICAL INVESTIGATION

Disulfide Bonds within the C2 Domain of RAGE Play Key Roles in Its Dimerization and Biogenesis

(2012) Wen Wei et al.   PLoS One

The expression of the receptor for advanced glycation endproducts (RAGE) is permissive for early pancreatic neoplasia

(2012) R. Kang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RhoB regulates cell migration through altered focal adhesion dynamics

(2012) F. M. Vega et al.   Open Biology

Association of serum soluble Receptor for Advanced Glycation End-products with subclinical cerebrovascular disease: The Northern Manhattan Study (NOMAS)

(2011) Barry I. Hudson et al.   ATHEROSCLEROSIS

Function ofERBB4is determined by alternative splicing

(2011) Ville Veikkolainen et al.   CELL CYCLE

Soluble receptor for AGE (RAGE) is a novel independent predictor of all-cause and cardiovascular mortality in type 1 diabetes

(2011) M. C. Thomas et al.   DIABETOLOGIA

Receptor for Advanced Glycation End Products (RAGE) Prevents Endothelial Cell Membrane Resealing and Regulates F-actin Remodeling in a β-Catenin-dependent Manner

(2011) Fei Xiong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

S100A8/A9 Activate Key Genes and Pathways in Colon Tumor Progression

(2011) M. Ichikawa et al.   MOLECULAR CANCER RESEARCH

PKCα and PKCδ Regulate ADAM17-Mediated Ectodomain Shedding of Heparin Binding-EGF through Separate Pathways

(2011) Marie Kveiborg et al.   PLoS One

TIRAP, an Adaptor Protein for TLR2/4, Transduces a Signal from RAGE Phosphorylated upon Ligand Binding

(2011) Masakiyo Sakaguchi et al.   PLoS One

Molecular and Cellular Mechanisms of Ectodomain Shedding

(2010) Kazutaka Hayashida et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

The cytoplasmic domains of TNFα-converting enzyme (TACE/ADAM17) and L-selectin are regulated differently by p38 MAPK and PKC to promote ectodomain shedding

(2010) David J. Killock et al.   BIOCHEMICAL JOURNAL

Alternatively Spliced RAGEv1 Inhibits Tumorigenesis through Suppression of JNK Signaling

(2010) A. Z. Kalea et al.   CANCER RESEARCH

Cantharidin, a potent and selective PP2A inhibitor, induces an oxidative stress-independent growth inhibition of pancreatic cancer cells through G2/M cell-cycle arrest and apoptosis

(2010) Wei Li et al.   CANCER SCIENCE

Ectodomain shedding of angiotensin converting enzyme 2 in human airway epithelia

(2009) Hong Peng Jia et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Active-site determinants of substrate recognition by the metalloproteinases TACE and ADAM10

(2009) Cristina I. Caescu et al.   BIOCHEMICAL JOURNAL

Jalview Version 2--a multiple sequence alignment editor and analysis workbench

(2009) A. M. Waterhouse et al.   BIOINFORMATICS

The receptor for advanced glycation end products (RAGE) sustains autophagy and limits apoptosis, promoting pancreatic tumor cell survival

(2009) R Kang et al.   CELL DEATH AND DIFFERENTIATION

RAGE: a novel biological and genetic marker for vascular disease

(2009) Anastasia Z. Kalea et al.   CLINICAL SCIENCE

Alternative splicing of the murine receptor for advanced glycation end-products (RAGE) gene

(2009) Anastasia Z. Kalea et al.   FASEB JOURNAL

Levels of Soluble Receptor for Advanced Glycation End Products in Acute Ischemic Stroke without a Source of Cardioembolism

(2009) Hyun-Young Park et al.   Journal of Clinical Neurology

Low levels of plasma soluble receptor for advanced glycation end products are associated with severe leukoaraiosis in acute stroke patients

(2009) Chiaki Yokota et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Human S100A12: a novel key player in inflammation?

(2008) Jens Pietzsch et al.   AMINO ACIDS

Calcium-regulated intramembrane proteolysis of the RAGE receptor

(2008) Arnaud Galichet et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A soluble form of the receptor for advanced glycation endproducts (RAGE) is produced by proteolytic cleavage of the membrane-bound form by the sheddase a disintegrin and metalloprotease 10 (ADAM10)

(2008) Angela Raucci et al.   FASEB JOURNAL

Receptor for Advanced Glycation End Products Is Subjected to Protein Ectodomain Shedding by Metalloproteinases

(2008) Ling Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interaction of the RAGE Cytoplasmic Domain with Diaphanous-1 Is Required for Ligand-stimulated Cellular Migration through Activation of Rac1 and Cdc42

(2008) Barry I. Hudson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Etiologic Diagnosis of Ischemic Stroke Subtypes With Plasma Biomarkers

(2008) Joan Montaner et al.   STROKE

Identification, classification, and expression of RAGE gene splice variants

(2007) Barry I. Hudson et al.   FASEB JOURNAL