The Lipidated Peptidomimetic Lau-((S)-Aoc)-(Lys-βNphe)6-NH2Is a Novel Formyl Peptide Receptor 2 Agonist That Activates Both Human and Mouse Neutrophil NADPH Oxidase

Basic characteristics of the neutrophil receptors that recognize formylated peptides, a danger-associated molecular pattern generated by bacteria and mitochondria

(2016) Claes Dahlgren et al.   BIOCHEMICAL PHARMACOLOGY

A pepducin designed to modulate P2Y 2 R function interacts with FPR2 in human neutrophils and transfers ATP to an NADPH-oxidase-activating ligand through a receptor cross-talk mechanism

(2016) Michael Gabl et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The proteolytically stable peptidomimetic Pam-(Lys-βNSpe)6-NH2 selectively inhibits human neutrophil activation via formyl peptide receptor 2

(2015) Sarah Line Skovbakke et al.   BIOCHEMICAL PHARMACOLOGY

P2Y2 receptor signaling in neutrophils is regulated from inside by a novel cytoskeleton-dependent mechanism

(2015) Michael Gabl et al.   EXPERIMENTAL CELL RESEARCH

A neutrophil inhibitory pepducin derived from FPR1 expected to target FPR1 signaling hijacks the closely related FPR2 instead

(2015) Malene Winther et al.   FEBS LETTERS

New development in studies of formyl-peptide receptors: critical roles in host defense

(2015) L. Li et al.   JOURNAL OF LEUKOCYTE BIOLOGY

A novel receptor cross-talk between the ATP receptor P2Y2 and formyl peptide receptors reactivates desensitized neutrophils to produce superoxide

(2014) Karin Önnheim et al.   EXPERIMENTAL CELL RESEARCH

Identification of Formyl Peptides from Listeria monocytogenes and Staphylococcus aureus as Potent Chemoattractants for Mouse Neutrophils

(2014) E. L. Southgate et al.   JOURNAL OF IMMUNOLOGY

Lipidated α-Peptide/β-Peptoid Hybrids with Potent Anti-inflammatory Activity

(2014) Sarah L. Skovbakke et al.   JOURNAL OF MEDICINAL CHEMISTRY

A Pepducin Derived from the Third Intracellular Loop of FPR2 Is a Partial Agonist for Direct Activation of This Receptor in Neutrophils But a Full Agonist for Cross-Talk Triggered Reactivation of FPR2

(2014) Michael Gabl et al.   PLoS One

The leukocyte chemotactic receptor FPR2, but not the closely related FPR1, is sensitive to cell-penetrating pepducins with amino acid sequences descending from the third intracellular receptor loop

(2013) Huamei Forsman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Characterization of a Proteolytically Stable Multifunctional Host Defense Peptidomimetic

(2013) Rasmus D. Jahnsen et al.   CHEMISTRY & BIOLOGY

Reactivation of Desensitized Formyl Peptide Receptors by Platelet Activating Factor: A Novel Receptor Cross Talk Mechanism Regulating Neutrophil Superoxide Anion Production

(2013) Huamei Forsman et al.   PLoS One

High in vitro antimicrobial activity of β-peptoid–peptide hybrid oligomers against planktonic and biofilm cultures of Staphylococcus epidermidis

(2012) Yang Liu et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Structural Characterization and Inhibitory Profile of Formyl Peptide Receptor 2 Selective Peptides Descending from a PIP2-Binding Domain of Gelsolin

(2012) H. Forsman et al.   JOURNAL OF IMMUNOLOGY

Antimicrobial Activity of Peptidomimetics against Multidrug-Resistant Escherichia coli: A Comparative Study of Different Backbones

(2012) Rasmus D. Jahnsen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Human Formyl Peptide Receptor 2 Senses Highly Pathogenic Staphylococcus aureus

(2010) Dorothee Kretschmer et al.   Cell Host & Microbe

Antimicrobial, Hemolytic, and Cytotoxic Activities of β-Peptoid-Peptide Hybrid Oligomers: Improved Properties Compared to Natural AMPs

(2010) Christian A. Olsen et al.   CHEMBIOCHEM

Cutting Edge: A Critical Role for the G Protein-Coupled Receptor mFPR2 in Airway Inflammation and Immune Responses

(2010) K. Chen et al.   JOURNAL OF IMMUNOLOGY

Anti-Inflammatory Role of the Murine Formyl-Peptide Receptor 2: Ligand-Specific Effects on Leukocyte Responses and Experimental Inflammation

(2010) Neil Dufton et al.   JOURNAL OF IMMUNOLOGY

The FPR2-specific ligand MMK-1 activates the neutrophil NADPH-oxidase, but triggers no unique pathway for opening of plasma membrane calcium channels

(2009) Jennie Karlsson et al.   CELL CALCIUM

A methodological approach to studies of desensitization of the formyl peptide receptor: Role of the read out system, reactive oxygen species and the specific agonist used to trigger neutrophils

(2009) Jennie Karlsson et al.   JOURNAL OF IMMUNOLOGICAL METHODS

International Union of Basic and Clinical Pharmacology. LXXIII. Nomenclature for the Formyl Peptide Receptor (FPR) Family

(2009) R. D. Ye et al.   PHARMACOLOGICAL REVIEWS

Tumour necrosis factor (TNF)-α primes murine neutrophils when triggered via formyl peptide receptor-related sequence 2, the murine orthologue of human formyl peptide receptor-like 1, through a process involving the type I TNF receptor and subcellular granule mobilization

(2008) Karin Önnheim et al.   IMMUNOLOGY

Dimeric Building Blocks for Solid-Phase Synthesis of α-Peptide-β-Peptoid Chimeras

(2008) Christian Olsen et al.   SYNTHESIS-STUTTGART