A Pepducin Derived from the Third Intracellular Loop of FPR2 Is a Partial Agonist for Direct Activation of This Receptor in Neutrophils But a Full Agonist for Cross-Talk Triggered Reactivation of FPR2

The role of protein dynamics in GPCR function: insights from the β2AR and rhodopsin

(2014) Aashish Manglik et al.   CURRENT OPINION IN CELL BIOLOGY

A novel receptor cross-talk between the ATP receptor P2Y2 and formyl peptide receptors reactivates desensitized neutrophils to produce superoxide

(2014) Karin Önnheim et al.   EXPERIMENTAL CELL RESEARCH

Biasing GPCR Signaling from Inside

(2014) A. K. Shukla   Science Signaling

Functional selectivity of G-protein-coupled receptors: From recombinant systems to native human cells

(2013) Roland Seifert   BIOCHEMICAL PHARMACOLOGY

The leukocyte chemotactic receptor FPR2, but not the closely related FPR1, is sensitive to cell-penetrating pepducins with amino acid sequences descending from the third intracellular receptor loop

(2013) Huamei Forsman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Reactivation of Desensitized Formyl Peptide Receptors by Platelet Activating Factor: A Novel Receptor Cross Talk Mechanism Regulating Neutrophil Superoxide Anion Production

(2013) Huamei Forsman et al.   PLoS One

Pepducin targeting the C-X-C chemokine receptor type 4 acts as a biased agonist favoring activation of the inhibitory G protein

(2013) J. Quoyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Restructuring G-Protein- Coupled Receptor Activation

(2012) Martin Audet et al.   CELL

Turning Receptors On and Off with Intracellular Pepducins: New Insights into G-protein-coupled Receptor Drug Development

(2012) Katie O'Callaghan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of CXCR2 profoundly suppresses inflammation-driven and spontaneous tumorigenesis

(2012) Thomas Jamieson et al.   JOURNAL OF CLINICAL INVESTIGATION

Structural Characterization and Inhibitory Profile of Formyl Peptide Receptor 2 Selective Peptides Descending from a PIP2-Binding Domain of Gelsolin

(2012) H. Forsman et al.   JOURNAL OF IMMUNOLOGY

Regulation of GPCR activity, trafficking and localization by GPCR-interacting proteins

(2011) Ana C Magalhaes et al.   BRITISH JOURNAL OF PHARMACOLOGY

Ligand functional selectivity and quantitative pharmacology at G protein-coupled receptors

(2011) Wayne Stallaert et al.   Expert Opinion on Drug Discovery

Neutrophils cascading their way to inflammation

(2011) Christian D. Sadik et al.   TRENDS IN IMMUNOLOGY

Cytoskeletal regulation of chemotactic receptors: Molecular complexation of N-formyl peptide receptors with G proteins and actin

(2010) Algirdas J. Jesaitis et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Activation of human monocytes by a formyl peptide receptor 2-derived pepducin

(2010) Ha Young Lee et al.   FEBS LETTERS

The FPR2-specific ligand MMK-1 activates the neutrophil NADPH-oxidase, but triggers no unique pathway for opening of plasma membrane calcium channels

(2009) Jennie Karlsson et al.   CELL CALCIUM

A methodological approach to studies of desensitization of the formyl peptide receptor: Role of the read out system, reactive oxygen species and the specific agonist used to trigger neutrophils

(2009) Jennie Karlsson et al.   JOURNAL OF IMMUNOLOGICAL METHODS

International Union of Basic and Clinical Pharmacology. LXXIII. Nomenclature for the Formyl Peptide Receptor (FPR) Family

(2009) R. D. Ye et al.   PHARMACOLOGICAL REVIEWS

Regulation of G protein-coupled receptor signalling: Focus on the cardiovascular system and regulator of G protein signalling proteins

(2008) Mariëlle C. Hendriks-Balk et al.   EUROPEAN JOURNAL OF PHARMACOLOGY