COVID-19 and Aging-Related Genome (Chromosome) Instability in the Brain: Another Possible Time-Bomb of SARS-CoV-2 Infection

Mapping the SARS-CoV-2–Host Protein–Protein Interactome by Affinity Purification Mass Spectrometry and Proximity-Dependent Biotin Labeling: A Rational and Straightforward Route to Discover Host-Directed Anti-SARS-CoV-2 Therapeutics

(2021) Rosa Terracciano et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The SARS-CoV-2 RNA interactome

(2021) Sungyul Lee et al.   MOLECULAR CELL

Chromosome Instability, Aging and Brain Diseases

(2021) Ivan Y. Iourov et al.   Cells

ER Stress and Micronuclei Cluster: Stress Response Contributes to Genome Chaos in Cancer

(2021) Eric Heng et al.   Frontiers in Cell and Developmental Biology

Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modelling study

(2020) Joseph T Wu et al.   LANCET

Cellular Senescence in Neurodegenerative Diseases

(2020) Carmen Martínez-Cué et al.   Frontiers in Cellular Neuroscience

A Review of SARS-CoV-2 and the Ongoing Clinical Trials

(2020) Yung-Fang Tu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

(2020) David E. Gordon et al.   NATURE

Dynamic nature of somatic chromosomal mosaicism, genetic-environmental interactions and therapeutic opportunities in disease and aging

(2020) Svetlana G. Vorsanova et al.   Molecular Cytogenetics

Master Regulator Analysis of the SARS-CoV-2/Human Interactome

(2020) Pietro H. Guzzi et al.   Journal of Clinical Medicine

SARS-CoV-2 and the Nervous System: From Clinical Features to Molecular Mechanisms

(2020) Manuela Pennisi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

SARS-CoV-2 Molecular Network Structure

(2020) José Díaz   Frontiers in Physiology

The current landscape of coronavirus-host protein–protein interactions

(2020) Laure Perrin-Cocon et al.   Journal of Translational Medicine

Characteristics of SARS-CoV-2 and COVID-19

(2020) Ben Hu et al.   NATURE REVIEWS MICROBIOLOGY

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms

(2020) David E. Gordon et al.   SCIENCE

The SARS-CoV-2 RNA–protein interactome in infected human cells

(2020) Nora Schmidt et al.   Nature Microbiology

Ontogenetic and Pathogenetic Views on Somatic Chromosomal Mosaicism

(2019) Ivan Y. Iourov et al.   Genes

Chromosome Instability in the Neurodegenerating Brain

(2019) Yuri B. Yurov et al.   Frontiers in Genetics

Genomic mosaicism in the developing and adult brain

(2018) Suzanne Rohrback et al.   Developmental Neurobiology

Mitotic defects lead to neuronal aneuploidy and apoptosis in frontotemporal lobar degeneration caused by MAPT mutations

(2018) Julbert Caneus et al.   MOLECULAR BIOLOGY OF THE CELL

Somatic Mutagenesis in Mammals and Its Implications for Human Disease and Aging

(2018) Lei Zhang et al.   Annual Review of Genetics

Mechanisms and consequences of aneuploidy and chromosome instability in the aging brain

(2017) Grasiella A. Andriani et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Cohesion and the aneuploid phenotype in Alzheimer's disease: A tale of genome instability

(2015) Vladan Bajic et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

The DNA Replication Stress Hypothesis of Alzheimer’s Disease

(2012) Yuri B. Yurov et al.   TheScientificWorldJOURNAL

DNA repair deficiency in neurodegeneration

(2011) Dennis Kjølhede Jeppesen et al.   PROGRESS IN NEUROBIOLOGY

Ontogenetic Variation of the Human Genome

(2010) Y. Yurov et al.   CURRENT GENOMICS

Increased chromosome instability dramatically disrupts neural genome integrity and mediates cerebellar degeneration in the ataxia-telangiectasia brain

(2009) Ivan Y. Iourov et al.   HUMAN MOLECULAR GENETICS