Delicate regulation of IL-1β-mediated inflammation by cyclophilin A

Insights into the modulatory role of cyclosporine A and its research advances in acute inflammation

(2021) Qiuyi Gui et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The ubiquitylation of IL-1β limits its cleavage by caspase-1 and targets it for proteasomal degradation

(2021) Swarna L. Vijayaraj et al.   Nature Communications

Induction of cyclophilin A by influenza A virus infection facilitates group A Streptococcus coinfection

(2021) Xiaoyuan Bai et al.   Cell Reports

Cyclophilin A Plays Potential Roles in a Rat Model of Asthma and Suppression of Immune Response

(2021) Cai-Tao Chen et al.   Journal of Asthma and Allergy

Cyclophilin A is a key positive and negative feedback regulator within interleukin‐6 trans‐signaling pathway

(2021) Xiaohan Luan et al.   FASEB JOURNAL

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

Chronic IL-1β-induced inflammation regulates epithelial-to-mesenchymal transition memory phenotypes via epigenetic modifications in non-small cell lung cancer

(2020) Rui Li et al.   Scientific Reports

Cyclophilin A/EMMPRIN Axis Is Involved in Pro-Fibrotic Processes Associated with Thoracic Aortic Aneurysm of Marfan Syndrome Patients

(2020) Gianluca L. Perrucci et al.   Cells

Cyclophilin a knokdown inhibits cell migration and invasion through the suppression of epithelial–mesenchymal transition in colorectal cancer cells

(2020) Tetsushi Yamamoto et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mechanisms and Points of Control in the Spread of Inflammation: A Mathematical Investigation

(2020) A. Bayani et al.   BULLETIN OF MATHEMATICAL BIOLOGY

APOE4 leads to blood–brain barrier dysfunction predicting cognitive decline

(2020) Axel Montagne et al.   NATURE

Extracellular release of ATP promotes systemic inflammation during acute pancreatitis

(2019) Ajay Dixit et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

STAT3–CyPA signaling pathway in endothelial cell apoptosis

(2019) Yifan Xie et al.   CELLULAR SIGNALLING

Clonorchis sinensis cyclophilin A immunization protected mice from CLP-induced sepsis

(2018) Juan Jiang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Cyclophilin a increases CD68+ cell infiltration in rat experimental periodontitis

(2018) Lande Xue et al.   JOURNAL OF MOLECULAR HISTOLOGY

Inflammation induced by influenza virus impairs human innate immune control of pneumococcus

(2018) Simon P. Jochems et al.   NATURE IMMUNOLOGY

Cyclophilin A Aggravates Collagen-Induced Arthritis via Promoting Classically Activated Macrophages

(2017) Zhai Dongsheng et al.   INFLAMMATION

Pathogenetic insights from the treatment of rheumatoid arthritis

(2017) Iain B McInnes et al.   LANCET

Cyclophilin A promotes non-small cell lung cancer metastasis via p38 MAPK

(2017) Yinan Guo et al.   Thoracic Cancer

Cyclophilin A-regulated ubiquitination is critical for RIG-I-mediated antiviral immune responses

(2017) Wei Liu et al.   eLife

The purinergic receptor P2X5 regulates inflammasome activity and hyper-multinucleation of murine osteoclasts

(2017) Hyunsoo Kim et al.   Scientific Reports

SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling

(2016) Paul R. Elliott et al.   MOLECULAR CELL

Proteomic identification of cyclophilin A as a potential biomarker and therapeutic target in oral submucous fibrosis

(2016) Yao Yuan et al.   Oncotarget

A20 Restricts Ubiquitination of Pro-Interleukin-1β Protein Complexes and Suppresses NLRP3 Inflammasome Activity

(2015) Bao H. Duong et al.   IMMUNITY

The Cyclophilin A–CD147 complex promotes the proliferation and homing of multiple myeloma cells

(2015) Di Zhu et al.   NATURE MEDICINE

Dendritic Cell IL-1α and IL-1β Are Polyubiquitinated and Degraded by the Proteasome

(2014) Joseph S. Ainscough et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cyclophilin A (CypA) Interacts with NF-κB Subunit, p65/RelA, and Contributes to NF-κB Activation Signaling

(2014) Shan Sun et al.   PLoS One

The Interleukin-1 Family: Back to the Future

(2013) Cecilia Garlanda et al.   IMMUNITY

Interactions of the Extracellular Matrix and Progenitor Cells in Cutaneous Wound Healing

(2013) Susan W. Volk et al.   Advances in Wound Care

Cyclophilin A affects inflammation, virus elimination and myocardial fibrosis in coxsackievirus B3-induced myocarditis

(2012) Peter Seizer et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Apolipoprotein E controls cerebrovascular integrity via cyclophilin A

(2012) Robert D. Bell et al.   NATURE

ATP release and purinergic signaling: a common pathway for particle-mediated inflammasome activation

(2012) N Riteau et al.   Cell Death & Disease

Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β

(2011) Nicolas Dupont et al.   EMBO JOURNAL

Autophagy Controls IL-1β Secretion by Targeting Pro-IL-1β for Degradation

(2011) James Harris et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Inflammation 2010: New Adventures of an Old Flame

(2010) Ruslan Medzhitov   CELL

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

Cyclophilin A is an inflammatory mediator that promotes atherosclerosis in apolipoprotein E–deficient mice

(2010) Patrizia Nigro et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-1 pathways in inflammation and human diseases

(2010) Cem Gabay et al.   Nature Reviews Rheumatology

Cyclophilin A interacts with influenza A virus M1 protein and impairs the early stage of the viral replication

(2009) Xiaoling Liu et al.   CELLULAR MICROBIOLOGY

Universal sample preparation method for proteome analysis

(2009) Jacek R Wiśniewski et al.   NATURE METHODS

Differential requirement for the activation of the inflammasome for processing and release of IL-1  in monocytes and macrophages

(2008) M. G. Netea et al.   BLOOD

Mapping and quantifying mammalian transcriptomes by RNA-Seq

(2008) Ali Mortazavi et al.   NATURE METHODS