ZFP541 maintains the repression of pre-pachytene transcriptional programs and promotes male meiosis progression

Homozygous mutations in C14orf39/SIX6OS1 cause non-obstructive azoospermia and premature ovarian insufficiency in humans

(2021) Suixing Fan et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Four-pronged negative feedback of DSB machinery in meiotic DNA-break control in mice

(2021) Ihsan Dereli et al.   NUCLEIC ACIDS RESEARCH

KCTD19 and its associated protein ZFP541 are independently essential for meiosis in male mice

(2021) Seiya Oura et al.   PLoS Genetics

The CNOT4 Subunit of the CCR4‐NOT Complex is Involved in mRNA Degradation, Efficient DNA Damage Repair, and XY Chromosome Crossover during Male Germ Cell Meiosis

(2021) Xing‐Xing Dai et al.   Advanced Science

Meiosis-specific ZFP541 repressor complex promotes developmental progression of meiotic prophase towards completion during mouse spermatogenesis

(2021) Yuki Horisawa-Takada et al.   Nature Communications

Refined spatial temporal epigenomic profiling reveals intrinsic connection between PRDM9-mediated H3K4me3 and the fate of double-stranded breaks

(2020) Yao Chen et al.   CELL RESEARCH

MEIOSIN Directs the Switch from Mitosis to Meiosis in Mammalian Germ Cells

(2020) Kei-ichiro Ishiguro et al.   DEVELOPMENTAL CELL

The testis-specific LINC component SUN3 is essential for sperm head shaping during mouse spermiogenesis

(2020) Qian Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ensuring meiotic DNA break formation in the mouse pseudoautosomal region

(2020) Laurent Acquaviva et al.   NATURE

The BRCA2-MEILB2-BRME1 complex governs meiotic recombination and impairs the mitotic BRCA2-RAD51 function in cancer cells

(2020) Jingjing Zhang et al.   Nature Communications

Transcriptional activation during cell reprogramming correlates with the formation of 3D open chromatin hubs

(2020) Marco Di Stefano et al.   Nature Communications

ZCWPW1 is recruited to recombination hotspots by PRDM9, and is essential for meiotic double strand break repair

(2020) Daniel Wells et al.   eLife

A TOP6BL mutation abolishes meiotic DNA double-strand break formation and causes human infertility

(2020) Yuying Jiao et al.   Science Bulletin

A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis

(2019) Marcos Morgan et al.   CELL RESEARCH

Dynamic reorganization of the genome shapes the recombination landscape in meiotic prophase

(2019) Lucas Patel et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Reprogramming of Meiotic Chromatin Architecture during Spermatogenesis

(2019) Yao Wang et al.   MOLECULAR CELL

REC114 Partner ANKRD31 Controls Number, Timing, and Location of Meiotic DNA Breaks

(2019) Michiel Boekhout et al.   MOLECULAR CELL

Mouse ANKRD31 Regulates Spatiotemporal Patterning of Meiotic Recombination Initiation and Ensures Recombination between X and Y Sex Chromosomes

(2019) Frantzeskos Papanikos et al.   MOLECULAR CELL

Amplification of a broad transcriptional program by a common factor triggers the meiotic cell cycle in mice

(2019) Mina L Kojima et al.   eLife

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Meiosis I progression in spermatogenesis requires a type of testis-specific 20S core proteasome

(2019) Qianting Zhang et al.   Nature Communications

The ENCODE Blacklist: Identification of Problematic Regions of the Genome

(2019) Haley M. Amemiya et al.   Scientific Reports

Unified single-cell analysis of testis gene regulation and pathology in five mouse strains

(2019) Min Jung et al.   eLife

Identifying gene expression programs of cell-type identity and cellular activity with single-cell RNA-Seq

(2019) Dylan Kotliar et al.   eLife

The histone modification reader ZCWPW1 is required for meiosis prophase I in male but not in female mice

(2019) Miao Li et al.   Science Advances

Recovering Gene Interactions from Single-Cell Data Using Data Diffusion

(2018) David van Dijk et al.   CELL

SMC1α Substitutes for Many Meiotic Functions of SMC1β but Cannot Protect Telomeres from Damage

(2018) Uddipta Biswas et al.   CURRENT BIOLOGY

Batch effects in single-cell RNA-sequencing data are corrected by matching mutual nearest neighbors

(2018) Laleh Haghverdi et al.   NATURE BIOTECHNOLOGY

Single-cell RNA-seq uncovers dynamic processes and critical regulators in mouse spermatogenesis

(2018) Yao Chen et al.   CELL RESEARCH

Dimensionality reduction for visualizing single-cell data using UMAP

(2018) Etienne Becht et al.   NATURE BIOTECHNOLOGY

UMI-tools: modeling sequencing errors in Unique Molecular Identifiers to improve quantification accuracy

(2017) Tom Smith et al.   GENOME RESEARCH

A SUMO-ubiquitin relay recruits proteasomes to chromosome axes to regulate meiotic recombination

(2017) H. B. D. Prasada Rao et al.   SCIENCE

Emi2 Is Essential for Mouse Spermatogenesis

(2017) Lakshmi Gopinathan et al.   Cell Reports

The conserved RNA helicase YTHDC2 regulates the transition from proliferation to differentiation in the germline

(2017) Alexis S Bailey et al.   eLife

Control of Meiotic Crossovers: From Double-Strand Break Formation to Designation

(2016) Stephen Gray et al.   Annual Review of Genetics

Complex heatmaps reveal patterns and correlations in multidimensional genomic data

(2016) Zuguang Gu et al.   BIOINFORMATICS

Transcriptome analysis of highly purified mouse spermatogenic cell populations: gene expression signatures switch from meiotic-to postmeiotic-related processes at pachytene stage

(2016) Irene da Cruz et al.   BMC GENOMICS

Repair of Meiotic DNA Breaks and Homolog Pairing in Mouse Meiosis Requires a Minichromosome Maintenance (MCM) Paralog

(2016) Adrian J. McNairn et al.   GENETICS

Meiotic DNA break formation requires the unsynapsed chromosome axis-binding protein IHO1 (CCDC36) in mice

(2016) Marcello Stanzione et al.   NATURE CELL BIOLOGY

deepTools2: a next generation web server for deep-sequencing data analysis

(2016) Fidel Ramírez et al.   NUCLEIC ACIDS RESEARCH

A DNA topoisomerase VI-like complex initiates meiotic recombination

(2016) N. Vrielynck et al.   SCIENCE

The TopoVIB-Like protein family is required for meiotic DNA double-strand break formation

(2016) T. Robert et al.   SCIENCE

C14ORF39/SIX6OS1 is a constituent of the synaptonemal complex and is essential for mouse fertility

(2016) Laura Gómez-H et al.   Nature Communications

Implementation of meiosis prophase I programme requires a conserved retinoid-independent stabilizer of meiotic transcripts

(2016) Emilie Abby et al.   Nature Communications

Repair of Meiotic DNA Breaks and Homolog Pairing in Mouse Meiosis Requires a Minichromosome Maintenance (MCM) Paralog

(2016) Adrian J. McNairn et al.   GENETICS

ChIPseeker: an R/Bioconductor package for ChIP peak annotation, comparison and visualization

(2015) Guangchuang Yu et al.   BIOINFORMATICS

SCML2 Establishes the Male Germline Epigenome through Regulation of Histone H2A Ubiquitination

(2015) Kazuteru Hasegawa et al.   DEVELOPMENTAL CELL

Mechanisms of retinoic acid signalling and its roles in organ and limb development

(2015) Thomas J. Cunningham et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Multiple facets of histone variant H2AX: a DNA double-strand-break marker with several biological functions

(2015) Valentina Turinetto et al.   NUCLEIC ACIDS RESEARCH

Meiotic Recombination: The Essence of Heredity

(2015) Neil Hunter   Cold Spring Harbor Perspectives in Biology

The ATM Signaling Cascade Promotes Recombination-Dependent Pachytene Arrest in Mouse Spermatocytes

(2015) Sarai Pacheco et al.   PLoS Genetics

A Gene Regulatory Program for Meiotic Prophase in the Fetal Ovary

(2015) Y. Q. Shirleen Soh et al.   PLoS Genetics

Self-Organization of Meiotic Recombination Initiation: General Principles and Molecular Pathways

(2014) Scott Keeney et al.   Annual Review of Genetics

HSP70-binding protein HSPBP1 regulates chaperone expression at a posttranslational level and is essential for spermatogenesis

(2014) Christian Rogon et al.   MOLECULAR BIOLOGY OF THE CELL

Mechanism and Regulation of Meiotic Recombination Initiation

(2014) Isabel Lam et al.   Cold Spring Harbor Perspectives in Biology

The Meiotic Checkpoint Network: Step-by-Step through Meiotic Prophase

(2014) V. V. Subramanian et al.   Cold Spring Harbor Perspectives in Biology

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

RNF212 is a dosage-sensitive regulator of crossing-over during mammalian meiosis

(2013) April Reynolds et al.   NATURE GENETICS

Smart-seq2 for sensitive full-length transcriptome profiling in single cells

(2013) Simone Picelli et al.   NATURE METHODS

Target analysis by integration of transcriptome and ChIP-seq data with BETA

(2013) Su Wang et al.   Nature Protocols

Meiotic recombination in mammals: localization and regulation

(2013) Frédéric Baudat et al.   NATURE REVIEWS GENETICS

Mouse HFM1/Mer3 Is Required for Crossover Formation and Complete Synapsis of Homologous Chromosomes during Meiosis

(2013) Michel F. Guiraldelli et al.   PLoS Genetics

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Retinoic acid induces Sertoli cell paracrine signals for spermatogonia differentiation but cell autonomously drives spermatocyte meiosis

(2012) M. Raverdeau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Production of mouse pups from germline transmission-failed knockout chimeras

(2012) Yoshitaka Fujihara et al.   TRANSGENIC RESEARCH

A Novel Mouse Synaptonemal Complex Protein Is Essential for Loading of Central Element Proteins, Recombination, and Fertility

(2011) Sabine Schramm et al.   PLoS Genetics

Mutation of Eif4g3, encoding a eukaryotic translation initiation factor, causes male infertility and meiotic arrest of mouse spermatocytes

(2010) F. Sun et al.   DEVELOPMENT

Functional conservation of Mei4 for meiotic DNA double-strand break formation from yeasts to mice

(2010) R. Kumar et al.   GENES & DEVELOPMENT

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Asymmetric Distribution of UCH-L1 in Spermatogonia Is Associated With Maintenance and Differentiation of Spermatogonial Stem Cells

(2009) Jinping Luo et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Mouse HORMAD1 and HORMAD2, Two Conserved Meiotic Chromosomal Proteins, Are Depleted from Synapsed Chromosome Axes with the Help of TRIP13 AAA-ATPase

(2009) Lukasz Wojtasz et al.   PLoS Genetics

A Novel Germ Cell-specific Protein, SHIP1, Forms a Complex with Chromatin Remodeling Activity during Spermatogenesis

(2008) Eunyoung Choi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mouse TEX15 is essential for DNA double-strand break repair and chromosomal synapsis during male meiosis

(2008) Fang Yang et al.   JOURNAL OF CELL BIOLOGY

Retinoic acid in development: towards an integrated view

(2008) Karen Niederreither et al.   NATURE REVIEWS GENETICS

 -H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin

(2008) A. Kinner et al.   NUCLEIC ACIDS RESEARCH

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH

Stra8 and its inducer, retinoic acid, regulate meiotic initiation in both spermatogenesis and oogenesis in mice

(2008) E. L. Anderson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY