Meiotic recombination in mammals: localization and regulation

Suppression of genetic recombination in the pseudoautosomal region and at subtelomeres in mice with a hypomorphic Spo11 allele

(2013) Fatima Smagulova et al.   BMC GENOMICS

Programmed induction of DNA double strand breaks during meiosis: setting up communication between DNA and the chromosome structure

(2013) Valérie Borde et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Homologous Pairing Preceding SPO11-Mediated Double-Strand Breaks in Mice

(2013) Kingsley A. Boateng et al.   DEVELOPMENTAL CELL

Numerical constraints and feedback control of double-strand breaks in mouse meiosis

(2013) L. Kauppi et al.   GENES & DEVELOPMENT

Sequencing of isolated sperm cells for direct haplotyping of a human genome

(2013) E. F. Kirkness et al.   GENOME RESEARCH

RNF212 is a dosage-sensitive regulator of crossing-over during mammalian meiosis

(2013) April Reynolds et al.   NATURE GENETICS

Characterization of Prdm9 in Equids and Sterility in Mules

(2013) Cynthia C. Steiner et al.   PLoS One

Mechanistic basis of infertility of mouse intersubspecific hybrids

(2013) T. Bhattacharyya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Essential Developmental, Genomic Stability, and Tumour Suppressor Functions of the Mouse Orthologue of hSSB1/NABP2

(2013) Wei Shi et al.   PLoS Genetics

Mouse HFM1/Mer3 Is Required for Crossover Formation and Complete Synapsis of Homologous Chromosomes during Meiosis

(2013) Michel F. Guiraldelli et al.   PLoS Genetics

DNA binding specificities of the long zinc-finger recombination protein PRDM9

(2013) Timothy Billings et al.   GENOME BIOLOGY

Prdm3 and Prdm16 are H3K9me1 Methyltransferases Required for Mammalian Heterochromatin Integrity

(2012) Inês Pinheiro et al.   CELL

Genome-wide Single-Cell Analysis of Recombination Activity and De Novo Mutation Rates in Human Sperm

(2012) Jianbin Wang et al.   CELL

Meiotic DSBs and the control of mammalian recombination

(2012) Kenneth Paigen et al.   CELL RESEARCH

Mechanisms for recurrent and complex human genomic rearrangements

(2012) Pengfei Liu et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

DISSECTING THE GENETIC ARCHITECTURE OF F1HYBRID STERILITY IN HOUSE MICE

(2012) Maria Dzur-Gejdosova et al.   EVOLUTION

The mammalian synaptonemal complex: Protein components, assembly and role in meiotic recombination

(2012) Johanna Fraune et al.   EXPERIMENTAL CELL RESEARCH

Meiotic DNA double-strand breaks and chromosome asynapsis in mice are monitored by distinct HORMAD2-independent and -dependent mechanisms

(2012) L. Wojtasz et al.   GENES & DEVELOPMENT

HORMAD2 is essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity

(2012) Hiroshi Kogo et al.   GENES TO CELLS

HORMAD1-dependent checkpoint/surveillance mechanism eliminates asynaptic oocytes

(2012) Hiroshi Kogo et al.   GENES TO CELLS

Fine-Scale Maps of Recombination Rates and Hotspots in the Mouse Genome

(2012) Hadassa Brunschwig et al.   GENETICS

Sensitive mapping of recombination hotspots using sequencing-based detection of ssDNA

(2012) P. P. Khil et al.   GENOME RESEARCH

MCM8- and MCM9-Deficient Mice Reveal Gametogenesis Defects and Genome Instability Due to Impaired Homologous Recombination

(2012) Malik Lutzmann et al.   MOLECULAR CELL

Spp1, a Member of the Set1 Complex, Promotes Meiotic DSB Formation in Promoters by Tethering Histone H3K4 Methylation Sites to Chromosome Axes

(2012) Vérane Sommermeyer et al.   MOLECULAR CELL

Genetic recombination is directed away from functional genomic elements in mice

(2012) Kevin Brick et al.   NATURE

Homeostatic control of recombination is implemented progressively in mouse meiosis

(2012) Francesca Cole et al.   NATURE CELL BIOLOGY

Human aneuploidy: mechanisms and new insights into an age-old problem

(2012) So I. Nagaoka et al.   NATURE REVIEWS GENETICS

High Diversity at PRDM9 in Chimpanzees and Bonobos

(2012) Linn Fenna Groeneveld et al.   PLoS One

Recombination regulator PRDM9 influences the instability of its own coding sequence in humans

(2012) A. J. Jeffreys et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Fine-Scale Chimpanzee Genetic Map from Population Sequencing

(2012) A. Auton et al.   SCIENCE

Rad51 Is an Accessory Factor for Dmc1-Mediated Joint Molecule Formation During Meiosis

(2012) V. Cloud et al.   SCIENCE

The COMPASS Subunit Spp1 Links Histone Methylation to Initiation of Meiotic Recombination

(2012) L. Acquaviva et al.   SCIENCE

Probing Meiotic Recombination and Aneuploidy of Single Sperm Cells by Whole-Genome Sequencing

(2012) S. Lu et al.   SCIENCE

Interallelic and Intergenic Incompatibilities of the Prdm9 (Hst1) Gene in Mouse Hybrid Sterility

(2012) Petr Flachs et al.   PLoS Genetics

Genetic Variants in REC8, RNF212, and PRDM9 Influence Male Recombination in Cattle

(2012) Cynthia Sandor et al.   PLoS Genetics

The Genetics of Hybrid Incompatibilities

(2011) Shamoni Maheshwari et al.   Annual Review of Genetics

PRDM proteins: Important players in differentiation and disease

(2011) Cathrine K. Fog et al.   BIOESSAYS

The Impressionistic Landscape of Meiotic Recombination

(2011) Michael Lichten et al.   CELL

A Hierarchical Combination of Factors Shapes the Genome-wide Topography of Yeast Meiotic Recombination Initiation

(2011) Jing Pan et al.   CELL

Double duty for Exo1 during meiotic recombination

(2011) Neil Hunter   CELL CYCLE

Genetic Evidence That Synaptonemal Complex Axial Elements Govern Recombination Pathway Choice in Mice

(2011) Xin Chenglin Li et al.   GENETICS

Death of PRDM9 coincides with stabilization of the recombination landscape in the dog genome

(2011) E. Axelsson et al.   GENOME RESEARCH

Functional Analysis of KAP1 Genomic Recruitment

(2011) S. Iyengar et al.   MOLECULAR AND CELLULAR BIOLOGY

ATM controls meiotic double-strand-break formation

(2011) Julian Lange et al.   NATURE

Genome-wide analysis reveals novel molecular features of mouse recombination hotspots

(2011) Fatima Smagulova et al.   NATURE

The landscape of recombination in African Americans

(2011) Anjali G. Hinch et al.   NATURE

Meiotic homologue alignment and its quality surveillance are controlled by mouse HORMAD1

(2011) Katrin Daniel et al.   NATURE CELL BIOLOGY

Variation in Human Recombination Rates and Its Genetic Determinants

(2011) Adi Fledel-Alon et al.   PLoS One

Meiosis in Mice without a Synaptonemal Complex

(2011) Anna Kouznetsova et al.   PLoS One

Prdm9, a Major Determinant of Meiotic Recombination Hotspots, Is Not Functional in Dogs and Their Wild Relatives, Wolves and Coyotes

(2011) Violeta Muñoz-Fuentes et al.   PLoS One

Variants of the protein PRDM9 differentially regulate a set of human meiotic recombination hotspots highly active in African populations

(2011) I. L. Berg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The PR/SET domain in PRDM4 is preceded by a zinc knuckle

(2011) Klára Briknarová et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Distinct Properties of the XY Pseudoautosomal Region Crucial for Male Meiosis

(2011) L. Kauppi et al.   SCIENCE

What are the genomic drivers of the rapid evolution of PRDM9?

(2011) Chris P. Ponting   TRENDS IN GENETICS

Mouse PRDM9 DNA-Binding Specificity Determines Sites of Histone H3 Lysine 4 Trimethylation for Initiation of Meiotic Recombination

(2011) Corinne Grey et al.   PLOS BIOLOGY

The SSX Family of Cancer-Testis Antigens as Target Proteins for Tumor Therapy

(2010) Heath A. Smith et al.   Clinical & Developmental Immunology

Evidence that Meiotic Sex Chromosome Inactivation Is Essential for Male Fertility

(2010) Hélène Royo et al.   CURRENT BIOLOGY

Functional conservation of Mei4 for meiotic DNA double-strand break formation from yeasts to mice

(2010) R. Kumar et al.   GENES & DEVELOPMENT

Mammalian BLM helicase is critical for integrating multiple pathways of meiotic recombination

(2010) J. Kim Holloway et al.   JOURNAL OF CELL BIOLOGY

The Expression Profile of the Major Mouse SPO11 Isoforms Indicates that SPO11  Introduces Double Strand Breaks and Suggests that SPO11  Has an Additional Role in Prophase in both Spermatocytes and Oocytes

(2010) M. A. Bellani et al.   MOLECULAR AND CELLULAR BIOLOGY

Fine-scale recombination rate differences between sexes, populations and individuals

(2010) Augustine Kong et al.   NATURE

PRDM9 variation strongly influences recombination hot-spot activity and meiotic instability in humans

(2010) Ingrid L Berg et al.   NATURE GENETICS

Mammalian recombination hot spots: properties, control and evolution

(2010) Kenneth Paigen et al.   NATURE REVIEWS GENETICS

Patterns of Recombination Activity on Mouse Chromosome 11 Revealed by High Resolution Mapping

(2010) Timothy Billings et al.   PLoS One

Prdm9 Controls Activation of Mammalian Recombination Hotspots

(2010) E. D. Parvanov et al.   SCIENCE

Drive Against Hotspot Motifs in Primates Implicates the PRDM9 Gene in Meiotic Recombination

(2010) S. Myers et al.   SCIENCE

PRDM9 Is a Major Determinant of Meiotic Recombination Hotspots in Humans and Mice

(2010) F. Baudat et al.   SCIENCE

Mouse TRIP13/PCH2 Is Required for Recombination and Normal Higher-Order Chromosome Structure during Meiosis

(2010) Ignasi Roig et al.   PLoS Genetics

Hormad1 Mutation Disrupts Synaptonemal Complex Formation, Recombination, and Chromosome Segregation in Mammalian Meiosis

(2010) Yong-Hyun Shin et al.   PLoS Genetics

BRIT1/MCPH1 Is Essential for Mitotic and Meiotic Recombination DNA Repair and Maintaining Genomic Stability in Mice

(2010) Yulong Liang et al.   PLoS Genetics

Histone methyltransferase PRDM8 regulates mouse testis steroidogenesis

(2009) Gwang Hyeon Eom et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

DNA polymerase β is critical for mouse meiotic synapsis

(2009) Dawit Kidane et al.   EMBO JOURNAL

Distinct histone modifications define initiation and repair of meiotic recombination in the mouse

(2009) Jérôme Buard et al.   EMBO JOURNAL

A New Standard Genetic Map for the Laboratory Mouse

(2009) Allison Cox et al.   GENETICS

Oogenesis and cell death in human prenatal ovaries: what are the criteria for oocyte selection?

(2009) G.M. Hartshorne et al.   MOLECULAR HUMAN REPRODUCTION

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

The rise and fall of a human recombination hot spot

(2009) Alec J Jeffreys et al.   NATURE GENETICS

The consequences of asynapsis for mammalian meiosis

(2009) Paul S. Burgoyne et al.   NATURE REVIEWS GENETICS

Extraordinary Molecular Evolution in the PRDM9 Fertility Gene

(2009) James H. Thomas et al.   PLoS One

Accelerated Evolution of the Prdm9 Speciation Gene across Diverse Metazoan Taxa

(2009) Peter L. Oliver et al.   PLoS Genetics

Genetic Analysis of Variation in Human Meiotic Recombination

(2009) Reshmi Chowdhury et al.   PLoS Genetics

Meiotic failure in male mice lacking an X-linked factor

(2008) F. Yang et al.   GENES & DEVELOPMENT

Functional Role of BLAP75 in BLM-Topoisomerase IIIα-dependent Holliday Junction Processing

(2008) Steven Raynard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A common sequence motif associated with recombination hot spots and genome instability in humans

(2008) Simon Myers et al.   NATURE GENETICS

High-Resolution Mapping of Crossovers Reveals Extensive Variation in Fine-Scale Recombination Patterns Among Humans

(2008) G. Coop et al.   SCIENCE

Sequence Variants in the RNF212 Gene Associate with Genome-Wide Recombination Rate

(2008) A. Kong et al.   SCIENCE

A Mouse Speciation Gene Encodes a Meiotic Histone H3 Methyltransferase

(2008) O. Mihola et al.   SCIENCE

ZIP4H (TEX11) Deficiency in the Mouse Impairs Meiotic Double Strand Break Repair and the Regulation of Crossing Over

(2008) Carrie A. Adelman et al.   PLoS Genetics

The Recombinational Anatomy of a Mouse Chromosome

(2008) Kenneth Paigen et al.   PLoS Genetics

MUS81 Generates a Subset of MLH1-MLH3–Independent Crossovers in Mammalian Meiosis

(2008) J. Kim Holloway et al.   PLoS Genetics