Hempseed (Cannabis sativa) Peptide H3 (IGFLIIWV) Exerts Cholesterol-Lowering Effects in Human Hepatic Cell Line

Hempseed (Cannabis sativa) Peptides WVSPLAGRT and IGFLIIWV Exert Anti-inflammatory Activity in the LPS-Stimulated Human Hepatic Cell Line

(2022) Ivan Cruz-Chamorro et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Targeting AMPK by Statins: A Potential Therapeutic Approach

(2021) Sajad Dehnavi et al.   DRUGS

Investigation of the intestinal trans-epithelial transport and antioxidant activity of two hempseed peptides WVSPLAGRT (H2) and IGFLIIWV (H3)

(2021) Carlotta Bollati et al.   FOOD RESEARCH INTERNATIONAL

The VEGA suite of programs: an versatile platform for cheminformatics and drug design projects

(2020) Alessandro Pedretti et al.   BIOINFORMATICS

Processing, Nutrition, and Functionality of Hempseed Protein: A Review

(2019) Qingling Wang et al.   COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY

Worldwide burden of LDL cholesterol: implications in cardiovascular disease

(2019) Camilla Mattiuzzi et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Hempseed in food industry: Nutritional value, health benefits, and industrial applications

(2019) William Leonard et al.   COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY

Statins: An Under-Appreciated Asset for the Prevention and the Treatment of NAFLD or NASH and the Related Cardiovascular Risk

(2018) Vasilios G. Athyros et al.   Current Vascular Pharmacology

Inhibition of PCSK9D374Y/LDLR Protein–Protein Interaction by Computationally Designed T9 Lupin Peptide

(2018) Carmen Lammi et al.   ACS Medicinal Chemistry Letters

Hempseed Peptides Exert Hypocholesterolemic Effects with a Statin-Like Mechanism

(2017) Chiara Zanoni et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Exploration of Potentially Bioactive Peptides Generated from the Enzymatic Hydrolysis of Hempseed Proteins

(2017) Gilda Aiello et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Binding Space Concept: A New Approach To Enhance the Reliability of Docking Scores and Its Application to Predicting Butyrylcholinesterase Hydrolytic Activity

(2017) Giulio Vistoli et al.   Journal of Chemical Information and Modeling

Investigations on the hypocholesterolaemic activity of LILPKHSDAD and LTFPGSAED, two peptides from lupin β-conglutin: Focus on LDLR and PCSK9 pathways

(2017) Chiara Zanoni et al.   Journal of Functional Foods

Proanthocyanidins Attenuation of H2O2-Induced Oxidative Damage in Tendon-Derived Stem Cells via Upregulating Nrf-2 Signaling Pathway

(2017) Wenshuang Sun et al.   Biomed Research International

Citrus junos Tanaka peel ameliorates hepatic lipid accumulation in HepG2 cells and in mice fed a high-cholesterol diet

(2016) Eun Ju Shin et al.   BMC Complementary and Alternative Medicine

Pharmacological Targeting of the Atherogenic Dyslipidemia Complex: The Next Frontier in CVD Prevention Beyond Lowering LDL Cholesterol

(2016) Changting Xiao et al.   DIABETES

Lupin protein exerts cholesterol-lowering effects targeting PCSK9: From clinical evidences to elucidation of the in vitro molecular mechanism using HepG2 cells

(2016) Carmen Lammi et al.   Journal of Functional Foods

Hypocholesterolaemic Activity of Lupin Peptides: Investigation on the Crosstalk between Human Enterocytes and Hepatocytes Using a Co-Culture System Including Caco-2 and HepG2 Cells

(2016) Carmen Lammi et al.   Nutrients

A simple and high-throughput in-cell Western assay using HepG2 cell line for investigating the potential hypocholesterolemic effects of food components and nutraceutics

(2015) Carmen Lammi et al.   FOOD CHEMISTRY

Major Peptides from Amaranth (Amaranthus cruentus) Protein Inhibit HMG-CoA Reductase Activity

(2015) Rosana Soares et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Two Peptides from Soy β-Conglycinin Induce a Hypocholesterolemic Effect in HepG2 Cells by a Statin-Like Mechanism: Comparative in Vitro and in Silico Modeling Studies

(2015) Carmen Lammi et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

IAVPGEVA, IAVPTGVA, and LPYP, three peptides from soy glycinin, modulate cholesterol metabolism in HepG2 cells through the activation of the LDLR-SREBP2 pathway

(2015) Carmen Lammi et al.   Journal of Functional Foods

AMPK—Sensing Energy while Talking to Other Signaling Pathways

(2014) D. Grahame Hardie   Cell Metabolism

Inhibition ofPCSK9Transcription by Berberine Involves Down-regulation of Hepatic HNF1α Protein Expression through the Ubiquitin-Proteasome Degradation Pathway

(2014) Bin Dong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PCSK9 plays a significant role in cholesterol homeostasis and lipid transport in intestinal epithelial cells

(2013) Emile Levy et al.   ATHEROSCLEROSIS

Pravastatin accelerates ischemia-induced angiogenesis through AMP-activated protein kinase

(2009) Yasukatsu Izumi et al.   HYPERTENSION RESEARCH

Empirical Scoring Functions for Advanced Protein−Ligand Docking with PLANTS

(2009) Oliver Korb et al.   Journal of Chemical Information and Modeling

Regulation of HMGCoA Reductase Activity by Policosanol and Octacosadienol, a New Synthetic Analogue of Octacosanol

(2009) Simonetta Oliaro-Bosso et al.   LIPIDS

Anti-inflammatory effect of allylpyrocatechol in LPS-induced macrophages is mediated by suppression of iNOS and COX-2 via the NF-κB pathway

(2008) Debjani Sarkar et al.   INTERNATIONAL IMMUNOPHARMACOLOGY