Reelin Alterations, Behavioral Phenotypes, and Brain Anomalies in Schizophrenia: A Systematic Review of Insights From Rodent Models

Analysis of Reelin signaling and neurodevelopmental trajectory in primary cultured cortical neurons with RELN deletion identified in schizophrenia

(2021) Yumi Tsuneura et al.   NEUROCHEMISTRY INTERNATIONAL

DNA methylation meta-analysis reveals cellular alterations in psychosis and markers of treatment-resistant schizophrenia

(2021) Eilis Hannon et al.   eLife

Maternal Deprivation in Rats Decreases the Expression of Interneuron Markers in the Neocortex and Hippocampus

(2021) Milan Aksic et al.   Frontiers in Neuroanatomy

Microinjection of Reelin into the mPFC prevents MK-801-induced recognition memory impairment in mice

(2021) Masahito Sawahata et al.   PHARMACOLOGICAL RESEARCH

Genetic contributors to risk of schizophrenia in the presence of a 22q11.2 deletion

(2020) Isabelle Cleynen et al.   MOLECULAR PSYCHIATRY

Schizophrenia and Influenza at the Centenary of the 1918-1919 Spanish Influenza Pandemic: Mechanisms of Psychosis Risk

(2020) Adrianna P. Kępińska et al.   Frontiers in Psychiatry

Reelin Functions, Mechanisms of Action and Signaling Pathways During Brain Development and Maturation

(2020) Yves Jossin   Biomolecules

Behavioral Tasks Evaluating Schizophrenia-like Symptoms in Animal Models: A Recent Update

(2020) Mary Jasmin Ang et al.   Current Neuropharmacology

Association Between REELIN Gene Polymorphisms (rs7341475 and rs262355) and Risk of Schizophrenia: an Updated Meta-analysis

(2020) Sadiatul Marzan et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Reelin Supplementation Into the Hippocampus Rescues Abnormal Behavior in a Mouse Model of Neurodevelopmental Disorders

(2020) Daisuke Ibi et al.   Frontiers in Cellular Neuroscience

Maternal Immune Activation and the Development of Dopaminergic Neurotransmission of the Offspring: Relevance for Schizophrenia and Other Psychoses

(2020) Argel Aguilar-Valles et al.   Frontiers in Psychiatry

Understanding sex differences in long-term outcomes after a first episode of psychosis

(2020) Rosa Ayesa-Arriola et al.   npj Schizophrenia

Stress during critical periods of development and risk for schizophrenia

(2019) Felipe V. Gomes et al.   SCHIZOPHRENIA RESEARCH

Maternal Immune Activation and Related Factors in the Risk of Offspring Psychiatric Disorders

(2019) Fiona Conway et al.   Frontiers in Psychiatry

Reelin is modulated by diet-induced obesity and has direct actions on arcuate proopiomelanocortin neurons

(2019) Brandon L. Roberts et al.   Molecular Metabolism

Selective Inactivation of Reelin in Inhibitory Interneurons Leads to Subtle Changes in the Dentate Gyrus But Leaves Cortical Layering and Behavior Unaffected

(2019) Jasmine Pahle et al.   CEREBRAL CORTEX

A disintegrin and metalloproteinase with thrombospondin motifs 2 cleaves and inactivates Reelin in the postnatal cerebral cortex and hippocampus, but not in the cerebellum

(2019) Yuko Yamakage et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Dopaminergic control of ADAMTS2 expression through cAMP/CREB and ERK: molecular effects of antipsychotics

(2019) Fulgencio Ruso-Julve et al.   Translational Psychiatry

An Overview of Animal Models Related to Schizophrenia

(2018) Ian R. Winship et al.   CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE

Single-cell trajectory analysis of human homogenous neurons carrying a rare RELN variant

(2018) Yuko Arioka et al.   Translational Psychiatry

Secreted Metalloproteinase ADAMTS-3 Inactivates Reelin

(2017) Himari Ogino et al.   JOURNAL OF NEUROSCIENCE

Interaction of reelin and stress on immobility in the forced swim test but not dopamine-mediated locomotor hyperactivity or prepulse inhibition disruption: Relevance to psychotic and mood disorders

(2017) Michael J. Notaras et al.   SCHIZOPHRENIA RESEARCH

GABAergic Mechanisms in Schizophrenia: Linking Postmortem and In Vivo Studies

(2017) Jeroen C. de Jonge et al.   Frontiers in Psychiatry

The number of Purkinje neurons and their topology in the cerebellar vermis of normal and reln haplodeficient mouse

(2016) Chiara Magliaro et al.   ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER

A Complex Interaction Between Reduced Reelin Expression and Prenatal Organophosphate Exposure Alters Neuronal Cell Morphology

(2016) Brian R. Mullen et al.   ASN Neuro

Sensorimotor gating deficits are inheritable in an isolation-rearing paradigm in rats

(2016) Chih-Yuan Ko et al.   BEHAVIOURAL BRAIN RESEARCH

Reelin Regulates the Maturation of Dendritic Spines, Synaptogenesis and Glial Ensheathment of Newborn Granule Cells

(2016) Carles Bosch et al.   CEREBRAL CORTEX

Dorsal Forebrain-Specific Deficiency of Reelin-Dab1 Signal Causes Behavioral Abnormalities Related to Psychiatric Disorders

(2016) Hideaki Imai et al.   CEREBRAL CORTEX

Reelin: Neurodevelopmental Architect and Homeostatic Regulator of Excitatory Synapses

(2016) Catherine R. Wasser et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The effects of prenatal H1N1 infection at E16 on FMRP, glutamate, GABA, and reelin signaling systems in developing murine cerebellum

(2016) S. Hossein Fatemi et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Mice that lack the C-terminal region of Reelin exhibit behavioral abnormalities related to neuropsychiatric disorders

(2016) Kaori Sakai et al.   Scientific Reports

Behavioral and molecular neuroepigenetic alterations in prenatally stressed mice: relevance for the study of chromatin remodeling properties of antipsychotic drugs

(2016) E Dong et al.   Translational Psychiatry

Gene–environment interaction of reelin and stress in cognitive behaviours in mice: Implications for schizophrenia

(2015) Anna Schroeder et al.   BEHAVIOURAL BRAIN RESEARCH

Schizophrenia Gene Expression Profile Reverted to Normal Levels by Antipsychotics

(2015) Benedicto Crespo-Facorro et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Neuronal Heterotopias Affect the Activities of Distant Brain Areas and Lead to Behavioral Deficits

(2015) K. Ishii et al.   JOURNAL OF NEUROSCIENCE

Long-Term Effects of Prenatal Hypoxia on Schizophrenia-Like Phenotype in Heterozygous Reeler Mice

(2015) Kristy R. Howell et al.   MOLECULAR NEUROBIOLOGY

Reelin has a preventive effect on phencyclidine-induced cognitive and sensory-motor gating deficits

(2015) Kazuhiro Ishii et al.   NEUROSCIENCE RESEARCH

Prenatal Stress Down-Regulates Reelin Expression by Methylation of Its Promoter and Induces Adult Behavioral Impairments in Rats

(2015) Ismael Palacios-García et al.   PLoS One

SYRCLE’s risk of bias tool for animal studies

(2014) Carlijn R Hooijmans et al.   BMC Medical Research Methodology

Single and combined effects of prenatal immune activation and peripubertal stress on parvalbumin and reelin expression in the hippocampal formation

(2014) Sandra Giovanoli et al.   BRAIN BEHAVIOR AND IMMUNITY

Effects of prenatal hypoxia on schizophrenia-related phenotypes in heterozygous reeler mice: A gene×environment interaction study

(2014) Kristy R. Howell et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Alterations in the hippocampal and striatal catecholaminergic fiber densities of heterozygous reeler mice

(2014) S. Nullmeier et al.   NEUROSCIENCE

Sex-dependent alterations in BDNF-TrkB signaling in the hippocampus of reelin heterozygous mice: a role for sex steroid hormones

(2013) Rachel A. Hill et al.   JOURNAL OF NEUROCHEMISTRY

Prenatal Stress Induces Schizophrenia-Like Alterations of Serotonin 2A and Metabotropic Glutamate 2 Receptors in the Adult Offspring: Role of Maternal Immune System

(2013) T. Holloway et al.   JOURNAL OF NEUROSCIENCE

Nicotine Restores Wt-Like Levels of Reelin and GAD67 Gene Expression in Brain of Heterozygous Reeler Mice

(2013) Emilia Romano et al.   NEUROTOXICITY RESEARCH

Nicotine exposure during adolescence: cognitive performance and brain gene expression in adult heterozygous reeler mice

(2013) Emilia Romano et al.   PSYCHOPHARMACOLOGY

Perinatal phencyclidine administration decreases the density of cortical interneurons and increases the expression of neuregulin-1

(2013) Nevena V. Radonjić et al.   PSYCHOPHARMACOLOGY

Behaviour and hippocampus-specific changes in spiny mouse neonates after treatment of the mother with the viral-mimetic Poly I:C at mid-pregnancy

(2012) Udani Ratnayake et al.   BRAIN BEHAVIOR AND IMMUNITY

Reelin supplementation recovers sensorimotor gating, synaptic plasticity and associative learning deficits in the heterozygous reeler mouse

(2012) Justin T Rogers et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Inflammatory and immune response genes have significantly altered expression in schizophrenia

(2012) J Sainz et al.   MOLECULAR PSYCHIATRY

The involvement of Reelin in neurodevelopmental disorders

(2012) Timothy D. Folsom et al.   NEUROPHARMACOLOGY

Epigenetic modifications of GABAergic interneurons are associated with the schizophrenia-like phenotype induced by prenatal stress in mice

(2012) Francesco Matrisciano et al.   NEUROPHARMACOLOGY

Altered N-methyl-d-aspartate receptor function in reelin heterozygous mice: Male–female differences and comparison with dopaminergic activity

(2012) Maarten van den Buuse et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Vldlr overexpression causes hyperactivity in rats

(2012) Keiko Iwata et al.   Molecular Autism

Early Effects of Lipopolysaccharide-Induced Inflammation on Foetal Brain Development in Rat

(2011) Cristina A Ghiani et al.   ASN Neuro

Region-specific alteration of GABAergic markers in the brain of heterozygous reeler mice

(2011) S. Nullmeier et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Prenatal exposure to bacterial endotoxin reduces the number of GAD67- and reelin-immunoreactive neurons in the hippocampus of rat offspring

(2011) Dominique Nouel et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Sexual dimorphism in schizophrenia: is there a need for gender-based protocols?

(2011) Adrianna Mendrek et al.   Expert Review of Neurotherapeutics

Impairment of cognitive performance after reelin knockdown in the medial prefrontal cortex of pubertal or adult rats

(2011) Jan Brosda et al.   NEUROBIOLOGY OF DISEASE

A stereological comparison of GAD67 and reelin expression in the hippocampal stratum oriens of offspring from two mouse models of maternal inflammation during pregnancy

(2011) Louise Harvey et al.   NEUROPHARMACOLOGY

Overexpression of Reelin Prevents the Manifestation of Behavioral Phenotypes Related to Schizophrenia and Bipolar Disorder

(2011) Cátia M Teixeira et al.   NEUROPSYCHOPHARMACOLOGY

Neuropathological and Reelin Deficiencies in the Hippocampal Formation of Rats Exposed to MAM; Differences and Similarities with Schizophrenia

(2010) Julien Matricon et al.   PLoS One