Yishen Qingli Heluo Granule in the Treatment of Chronic Kidney Disease: Network Pharmacology Analysis and Experimental Validation

Danggui Buxue Decoction in the Treatment of Metastatic Colon Cancer: Network Pharmacology Analysis and Experimental Validation

(2021) Shi-Han Feng et al.   Drug Design Development and Therapy

Magnesium supplementation reduces inflammation in rats with induced chronic kidney disease

(2021) Rodrigo López‐Baltanás et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Jian-Pi-Yi-Shen Formula Ameliorates Oxidative Stress, Inflammation, and Apoptosis by Activating the Nrf2 Signaling in 5/6 Nephrectomized Rats

(2021) Fanyuan Zhou et al.   Frontiers in Pharmacology

Inhibition of cyclooxygenase‐2 enhanced intestinal epithelial homeostasis via suppressing β‐catenin signalling pathway in experimental liver fibrosis

(2021) Linhao Zhang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Main active components of Jiawei Gegen Qinlian decoction protects against ulcerative colitis under different dietary environments in a gut microbiota-dependent manner

(2021) Qinmei Li et al.   PHARMACOLOGICAL RESEARCH

Anti‑inflammation treatment for protection of hepatocytes and amelioration of hepatic fibrosis in rats

(2021) Shi Feng et al.   Experimental and Therapeutic Medicine

ZiBuPiYin Recipe Prevented and Treated Cognitive Decline in ZDF Rats With Diabetes-Associated Cognitive Decline via Microbiota–Gut–Brain Axis Dialogue

(2021) Tingting Bi et al.   Frontiers in Cell and Developmental Biology

The mechanisms of Chuanxiong Rhizoma in treating spinal cord injury based on network pharmacology and experimental verification

(2021) Bo Tao et al.   Annals of Translational Medicine

Altered Emotional Phenotypes in Chronic Kidney Disease Following 5/6 Nephrectomy

(2021) Yeon Hee Yu et al.   Brain Sciences

Traditional Chinese medicine in the treatment of nonalcoholic steatohepatitis

(2021) Mingtai Chen et al.   PHARMACOLOGICAL RESEARCH

Luteolin Attenuates Diabetic Nephropathy through Suppressing Inflammatory Response and Oxidative Stress by Inhibiting STAT3 Pathway

(2020) Miaoyuan Zhang et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Global, regional, and national burden of chronic kidney disease, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

(2020) Boris Bikbov et al.   LANCET

ACE Inhibitor Benefit to Kidney and Cardiovascular Outcomes for Patients with Non-Dialysis Chronic Kidney Disease Stages 3–5: A Network Meta-Analysis of Randomised Clinical Trials

(2020) Yaru Zhang et al.   DRUGS

Deciphering the Pharmacological Mechanisms of Taohe-Chengqi Decoction Extract Against Renal Fibrosis Through Integrating Network Pharmacology and Experimental Validation In Vitro and In Vivo

(2020) Shanshan Zhou et al.   Frontiers in Pharmacology

Distinct Responses of Gut Microbiota to Jian-Pi-Yi-Shen Decoction Are Associated With Improved Clinical Outcomes in 5/6 Nephrectomized Rats

(2020) Lin Zheng et al.   Frontiers in Pharmacology

Crosstalk between obesity, diabetes, and alzheimer’s disease: Introducing quercetin as an effective triple herbal medicine

(2020) Shiva Ebrahimpour et al.   AGEING RESEARCH REVIEWS

When should we start and stop ACEi/ARB in paediatric chronic kidney disease?

(2020) Eugene Yu-hin Chan et al.   PEDIATRIC NEPHROLOGY

Integrated Network Pharmacology Analysis and Pharmacological Evaluation to Explore the Active Components and Mechanism of Abelmoschus manihot (L.) Medik. on Renal Fibrosis

(2020) Lifei Gu et al.   Drug Design Development and Therapy

Role of gut microbiota in identification of novel TCM-derived active metabolites

(2020) Tzu-Lung Lin et al.   Protein & Cell

Antidiabetic Effects of Gegen Qinlian Decoction via the Gut Microbiota Are Attributable to Its Key Ingredient Berberine

(2020) Xizhan Xu et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Kaempferol attenuates streptozotocin-induced diabetic nephropathy by downregulating TRAF6 expression: The role of TRAF6 in diabetic nephropathy

(2020) Wu Luo et al.   JOURNAL OF ETHNOPHARMACOLOGY

Knockdown of periostin attenuates 5/6 nephrectomy‐induced intrarenal renin–angiotensin system activation, fibrosis, and inflammation in rats

(2019) Xiaohui Bian et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Gegen Qinlian decoction enhances the effect of PD-1 blockade in colorectal cancer with microsatellite stability by remodelling the gut microbiota and the tumour microenvironment

(2019) Ji Lv et al.   Cell Death & Disease

Microbiome–metabolomics reveals gut microbiota associated with glycine-conjugated metabolites and polyamine metabolism in chronic kidney disease

(2019) Ya-Long Feng et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Targeting ROS and cPLA2/COX2 Expressions Ameliorated Renal Damage in Obese Mice with Endotoxemia

(2019) Jia-Feng Chang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The role of diet and intestinal microbiota in the development of metabolic syndrome

(2019) Jose A. Santos-Marcos et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Early B Cell Factor 1 (EBF1) Regulates Glomerular Development by Controlling Mesangial Maturation and Consequently COX-2 Expression

(2019) Tracy Nelson et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Gut microbiota in phytopharmacology: A comprehensive overview of concepts, reciprocal interactions, biotransformations and mode of actions

(2019) Priyankar Dey   PHARMACOLOGICAL RESEARCH

Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease

(2019) LaTonya J. Hickson et al.   EBioMedicine

Exercise prevents high fat diet-induced bone loss, marrow adiposity and dysbiosis in male mice

(2018) Laura R. McCabe et al.   BONE

Evaluation of AutoDock and AutoDock Vina on the CASF-2013 benchmark

(2018) Thomas Gaillard   Journal of Chemical Information and Modeling

Disorder of gut amino acids metabolism during CKD progression is related with gut microbiota dysbiosis and metagenome change

(2018) Yang Liu et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Quercetin is able to alleviate TGF‑β‑induced fibrosis in renal tubular epithelial cells by suppressing miR‑21

(2018) Yaochen Cao et al.   Experimental and Therapeutic Medicine

Renoprotective effects of the novel prostaglandin EP4 receptor-selective antagonist ASP7657 in 5/6 nephrectomized chronic kidney disease rats

(2018) Kazuhiko Mizukami et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

P53 in kidney injury and repair: Mechanism and therapeutic potentials

(2018) Chengyuan Tang et al.   PHARMACOLOGY & THERAPEUTICS

Network Pharmacology to Unveil the Biological Basis of Health-Strengthening Herbal Medicine in Cancer Treatment

(2018) Jiahui Zheng et al.   Cancers

Impacts of dietary silver nanoparticles and probiotic administration on the microbiota of an in-vitro gut model

(2018) Cristina Cattò et al.   ENVIRONMENTAL POLLUTION

Dahuang Zexie Decoction Protects against High-Fat Diet-Induced NAFLD by Modulating Gut Microbiota-Mediated Toll-Like Receptor 4 Signaling Activation and Loss of Intestinal Barrier

(2017) Jing Fang et al.   Evidence-based Complementary and Alternative Medicine

Understanding the Molecular Mechanisms of the Interplay Between Herbal Medicines and Gut Microbiota

(2017) Jun Xu et al.   MEDICINAL RESEARCH REVIEWS

Coexpression of NOS2 and COX2 accelerates tumor growth and reduces survival in estrogen receptor-negative breast cancer

(2017) Debashree Basudhar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emodin ameliorates cisplatin-induced apoptosis of rat renal tubular cells in vitro by activating autophagy

(2016) Hong Liu et al.   ACTA PHARMACOLOGICA SINICA

Worldwide access to treatment for end-stage kidney disease: a systematic review

(2015) Thaminda Liyanage et al.   LANCET

TCMSP: a database of systems pharmacology for drug discovery from herbal medicines

(2014) Jinlong Ru et al.   Journal of Cheminformatics

The Uremic Toxin Indoxyl Sulphate Enhances Macrophage Response to LPS

(2013) Simona Adesso et al.   PLoS One

Renoprotective Effect of Renin-Angiotensin-Aldosterone System Blockade in Patients With Predialysis Advanced Chronic Kidney Disease, Hypertension, and Anemia

(2013) Ta-Wei Hsu et al.   JAMA Internal Medicine

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Angiotensin-receptor blockade and risk of cancer: meta-analysis of randomised controlled trials

(2010) Ilke Sipahi et al.   LANCET ONCOLOGY

Antihypertensive drugs and risk of cancer: network meta-analyses and trial sequential analyses of 324 168 participants from randomised trials

(2010) Sripal Bangalore et al.   LANCET ONCOLOGY