KOtBu-Catalyzed 1,2-Silaboration of N-Heteroarenes to Access 2-Silylheterocycles: A Cooperative Model for the Regioselectivity

Phosphorus(III)-assisted regioselective C–H silylation of heteroarenes

(2021) Dingyi Wang et al.   Nature Communications

Chelation‐driven Regioselective 1,2‐Dearomatizations of N‐Aromatic Zwitterions

(2021) Donguk Ko et al.   BULLETIN OF THE KOREAN CHEMICAL SOCIETY

Substituted Dihydropyridine Synthesis by Dearomatization of Pyridines

(2021) Arne Heusler et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalyst-free carbosilylation of alkenes using silyl boronates and organic fluorides via selective C-F bond activation

(2021) Jun Zhou et al.   Nature Communications

Silylboronate-Mediated Defluorosilylation of Aryl Fluorides with or without Ni-Catalyst

(2021) Jun Zhou et al.   Frontiers in Chemistry

Iridium-Catalyzed Silylation of Five-Membered Heteroarenes: High Sterically Derived Selectivity from a Pyridyl-Imidazoline Ligand

(2020) Caleb Karmel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent Advances in Catalytic Dearomative Hydroboration of N‐Heteroarenes

(2020) Sehoon Park   ChemCatChem

NHC-Catalyzed 1,2-Selective Hydroboration of Quinolines

(2020) Jinseong Jeong et al.   ACS Catalysis

Transition‐Metal‐Free C−H Silylation: An Emerging Strategy

(2020) Arpana Tyagi et al.   Asian Journal of Organic Chemistry

Copper(I)-catalyzed Stereoselective Silylative Dearomatization of Indoles and Pyrroles Using Silylboronates

(2020) Keiichi Hayama et al.   CHEMISTRY LETTERS

In Situ Generation of Silyl Anion Species through Si−B Bond Activation for the Concerted Nucleophilic Aromatic Substitution of Fluoroarenes

(2019) Kumiko Kojima et al.   ChemPlusChem

Alkoxide‐Promoted Selective Hydroboration of N ‐Heteroarenes: Pivotal Roles of in situ Generated BH 3 in the Dearomatization Process

(2019) Eunchan Jeong et al.   CHEMISTRY-A EUROPEAN JOURNAL

Iridium-Catalyzed Silylation of C–H Bonds in Unactivated Arenes: A Sterically Encumbered Phenanthroline Ligand Accelerates Catalysis

(2019) Caleb Karmel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Transition-Metal-Free Direct C−H Silylation of Electron-Deficient Heteroarenes with Hydrosilanes via a Radical Mechanism

(2018) Ryu Sakamoto et al.   Asian Journal of Organic Chemistry

Base-Mediated Defluorosilylation of C(sp2 )−F and C(sp3 )−F Bonds

(2018) Xiang-Wie Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Mild and Direct Site-Selective sp2 C–H Silylation of (Poly)Azines

(2018) Yiting Gu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Defluorosilylation of fluoroarenes and fluoroalkanes

(2018) Benqiang Cui et al.   Nature Communications

Quest for Novel Chemical Entities through Incorporation of Silicon in Drug Scaffolds

(2017) Remya Ramesh et al.   JOURNAL OF MEDICINAL CHEMISTRY

Utilization of a Trimethylsilyl Group as a Synthetic Equivalent of a Hydroxyl Group via Chemoselective C(sp3)–H Borylation at the Methyl Group on Silicon

(2017) Takeru Torigoe et al.   JOURNAL OF ORGANIC CHEMISTRY

B(C6F5)3-Catalyzed (Convergent) Disproportionation Reaction of Indoles

(2017) Yuxi Han et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Free-Radical-Promoted Site-Selective C–H Silylation of Arenes by Using Hydrosilanes

(2017) Zhengbao Xu et al.   ORGANIC LETTERS

N-Heterocycle-Ligated Borocations as Highly Tunable Carbon Lewis Acids

(2017) James E. Radcliffe et al.   ORGANOMETALLICS

A well-defined NHC–Ir(iii) catalyst for the silylation of aromatic C–H bonds: substrate survey and mechanistic insights

(2017) Laura Rubio-Pérez et al.   Chemical Science

Synthesis of Enantiomerically Enriched Chiral Tetrahydroquinolines via Sequential Dearomatization/Enantioselective Borylation Reactions

(2016) Koji Kubota et al.   ADVANCED SYNTHESIS & CATALYSIS

Friedel-Crafts-Type Intermolecular C−H Silylation of Electron-Rich Arenes Initiated by Base-Metal Salts

(2016) Qin Yin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Electrophilic Aromatic Substitution with Silicon Electrophiles: Catalytic Friedel-Crafts C−H Silylation

(2016) Susanne Bähr et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

4-Position-Selective C–H Perfluoroalkylation and Perfluoroarylation of Six-Membered Heteroaromatic Compounds

(2016) Masahiro Nagase et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Brønsted Acid-Promoted Formation of Stabilized Silylium Ions for Catalytic Friedel–Crafts C–H Silylation

(2016) Qing-An Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Selective Functionalization of Pyridines via Heterocyclic Phosphonium Salts

(2016) Michael C. Hilton et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Electrophilic CH Silylation of Pyridines Enabled by Temporary Dearomatization

(2015) Simon Wübbolt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Silylation of Unactivated C–H Bonds

(2015) Chen Cheng et al.   CHEMICAL REVIEWS

Reaction Mechanism of the Anomalous Formal Nucleophilic Borylation of Organic Halides with Silylborane: Combined Theoretical and Experimental Studies

(2015) Ryohei Uematsu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Selective Silylative Reduction of Pyridines Leading to Structurally Diverse Azacyclic Compounds with the Formation of sp3 C–Si Bonds

(2015) Narasimhulu Gandhamsetty et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iridium-Catalyzed Silylation of Aryl C–H Bonds

(2015) Chen Cheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Silylation of C–H bonds in aromatic heterocycles by an Earth-abundant metal catalyst

(2015) Anton A. Toutov et al.   NATURE

Catalytic C–H bond silylation of aromatic heterocycles

(2015) Anton A Toutov et al.   Nature Protocols

Boryl substitution of functionalized aryl-, heteroaryl- and alkenyl halides with silylborane and an alkoxy base: expanded scope and mechanistic studies

(2015) Eiji Yamamoto et al.   Chemical Science

Silylative Cyclopropanation of Allyl Phosphates with Silylboronates

(2014) Ryo Shintani et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Boron-Catalyzed Silylative Reduction of Quinolines: Selective sp3 C–Si Bond Formation

(2014) Narasimhulu Gandhamsetty et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cobalt-Catalyzed C–H Borylation

(2014) Jennifer V. Obligacion et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium-Catalyzed Intermolecular C-H Silylation of Arenes with High Steric Regiocontrol

(2014) C. Cheng et al.   SCIENCE

Transition-Metal-Free BF3-Mediated Regioselective Direct Alkylation and Arylation of Functionalized Pyridines Using Grignard or Organozinc Reagents

(2013) Quan Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dearomatizing conversion of pyrazines to 1,4-dihydropyrazine derivatives via transition-metal-free diboration, silaboration, and hydroboration

(2012) Kazuyuki Oshima et al.   CHEMICAL COMMUNICATIONS

Potassium tert-butoxide-mediated regioselective silaboration of aromatic alkenes

(2012) Hajime Ito et al.   CHEMICAL COMMUNICATIONS

Organosilicon Molecules with Medicinal Applications

(2012) Annaliese K. Franz et al.   JOURNAL OF MEDICINAL CHEMISTRY

Gold-Catalyzed Direct Arylation

(2012) L. T. Ball et al.   SCIENCE

Cooperative Catalytic Activation of Si−H Bonds by a Polar Ru−S Bond: Regioselective Low-Temperature C−H Silylation of Indoles under Neutral Conditions by a Friedel−Crafts Mechanism

(2011) Hendrik F. T. Klare et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Regioselective Silaboration of Pyridines Leading to the Synthesis of Silylated Dihydropyridines

(2011) Kazuyuki Oshima et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Selective C-4 Alkylation of Pyridine by Nickel/Lewis Acid Catalysis

(2010) Yoshiaki Nakao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct C−H Arylation of Electron-Deficient Heterocycles with Arylboronic Acids

(2010) Ian B. Seiple et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Efficient Iridium-Catalyzed CH Functionalization/Silylation of Heteroarenes

(2008) Biao Lu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Strategy for C−H Activation of Pyridines:  Direct C-2 Selective Alkenylation of Pyridines by Nickel/Lewis Acid Catalysis

(2008) Yoshiaki Nakao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY