MyD88 in hepatic stellate cells enhances liver fibrosis via promoting macrophage M1 polarization

Hepatic fibrosis 2022: Unmet needs and a blueprint for the future

(2021) Scott L. Friedman et al.   HEPATOLOGY

MyD88 in Macrophages Enhances Liver Fibrosis by Activation of NLRP3 Inflammasome in HSCs

(2021) Shuang Ge et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

S100A4 promotes hepatocellular carcinogenesis by intensifying fibrosis-associated cancer cell stemness

(2020) Yanan Li et al.   OncoImmunology

Toll-like Receptors and the Control of Immunity

(2020) Katherine A. Fitzgerald et al.   CELL

Author Correction: Dioscin alleviates alcoholic liver fibrosis by attenuating hepatic stellate cell activation via the TLR4/MyD88/NF-κB signaling pathway

(2020) Min Liu et al.   Scientific Reports

The systemic inflammation hypothesis: Towards a new paradigm of acute decompensation and multiorgan failure in cirrhosis

(2020) Vicente Arroyo et al.   JOURNAL OF HEPATOLOGY

Extracellular histones stimulate collagen expression in vitro and promote liver fibrogenesis in a mouse model via the TLR4-MyD88 signaling pathway

(2020) Zhi Wang et al.   WORLD JOURNAL OF GASTROENTEROLOGY

The Power of Plasticity—Metabolic Regulation of Hepatic Stellate Cells

(2020) Parth Trivedi et al.   Cell Metabolism

Disrupting the TRIB3-SQSTM1 interaction reduces liver fibrosis by restoring autophagy and suppressing exosome-mediated HSC activation

(2019) Xiao-Wei Zhang et al.   Autophagy

Diversity, Mechanisms, and Significance of Macrophage Plasticity

(2019) Massimo Locati et al.   Annual Review of Pathology-Mechanisms of Disease

Pulmonary fibroblasts-secreted CXCL10 polarizes alveolar macrophages under pro-inflammatory stimuli

(2019) Cheng-Fang Tsai et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Effects of the gut–liver axis on ischaemia-mediated hepatocellular carcinoma recurrence in the mouse liver

(2018) Lorenzo A. Orci et al.   JOURNAL OF HEPATOLOGY

The immunology of hepatocellular carcinoma

(2018) Marc Ringelhan et al.   NATURE IMMUNOLOGY

S100A4 blockage alleviates agonistic anti-CD137 antibody-induced liver pathology without disruption of antitumor immunity

(2018) Jinhua Zhang et al.   OncoImmunology

Liver fibrosis: Pathophysiology, pathogenetic targets and clinical issues

(2018) Maurizio Parola et al.   MOLECULAR ASPECTS OF MEDICINE

The role of macrophages in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis

(2018) Konstantin Kazankov et al.   Nature Reviews Gastroenterology & Hepatology

Liver inflammation and fibrosis

(2017) Yukinori Koyama et al.   JOURNAL OF CLINICAL INVESTIGATION

Targeting hepatic macrophages to treat liver diseases

(2017) Frank Tacke   JOURNAL OF HEPATOLOGY

Mechanisms of hepatic stellate cell activation

(2017) Takuma Tsuchida et al.   Nature Reviews Gastroenterology & Hepatology

Macrophage Phenotype in Liver Injury and Repair

(2017) Y.-Y. Sun et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Pericyte MyD88 and IRAK4 control inflammatory and fibrotic responses to tissue injury

(2016) Irina A. Leaf et al.   JOURNAL OF CLINICAL INVESTIGATION

Mechanisms of CCl4-induced liver fibrosis with combined transcriptomic and proteomic analysis

(2016) Shu Dong et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Liver fibrosis and hepatic stellate cells: Etiology, pathological hallmarks and therapeutic targets

(2016) Chong-Yang Zhang et al.   WORLD JOURNAL OF GASTROENTEROLOGY

CXCL10-Mediates Macrophage, but not Other Innate Immune Cells-Associated Inflammation in Murine Nonalcoholic Steatohepatitis

(2016) Kyoko Tomita et al.   Scientific Reports

TLR-independent anti-inflammatory function of intestinal epithelial TRAF6 signalling prevents DSS-induced colitis in mice

(2015) Katerina Vlantis et al.   GUT

Liver fibrosis occurs through dysregulation of MyD88-dependent innate B-cell activity

(2015) Manoj Thapa et al.   HEPATOLOGY

S100A4 promotes liver fibrosis via activation of hepatic stellate cells

(2015) Lin Chen et al.   JOURNAL OF HEPATOLOGY

Dioscin alleviates alcoholic liver fibrosis by attenuating hepatic stellate cell activation via the TLR4/MyD88/NF-κB signaling pathway

(2015) Min Liu et al.   Scientific Reports

Effect of Surface Modification and Macrophage Phenotype on Particle Internalization

(2014) Daniel Wang et al.   BIOMACROMOLECULES

Hepatic macrophages but not dendritic cells contribute to liver fibrosis by promoting the survival of activated hepatic stellate cells in mice

(2013) Jean-Philippe Pradere et al.   HEPATOLOGY

Promotion of Hepatocellular Carcinoma by the Intestinal Microbiota and TLR4

(2012) Dianne H. Dapito et al.   CANCER CELL

Role of innate immunity and the microbiota in liver fibrosis: crosstalk between the liver and gut

(2011) Ekihiro Seki et al.   JOURNAL OF PHYSIOLOGY-LONDON

In Vivo Fate Mapping Identifies Mesenchymal Progenitor Cells

(2011) Danka Grcevic et al.   STEM CELLS

CXCL10 promotes liver fibrosis by prevention of NK cell mediated hepatic stellate cell inactivation

(2010) Edith Hintermann et al.   JOURNAL OF AUTOIMMUNITY

Role of TLR9 in hepatic stellate cells and experimental liver fibrosis

(2008) Erwin Gäbele et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

STAT3 is a Critical Regulator of Astrogliosis and Scar Formation after Spinal Cord Injury

(2008) J. E. Herrmann et al.   JOURNAL OF NEUROSCIENCE