Neu1 Is Released From Activated Microglia, Stimulating Microglial Phagocytosis and Sensitizing Neurons to Glutamate

Microglial phagocytosis of neurons in neurodegeneration, and its regulation

(2021) Claire A Butler et al.   JOURNAL OF NEUROCHEMISTRY

Neuronal Loss after Stroke Due to Microglial Phagocytosis of Stressed Neurons

(2021) Guy C. Brown   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Lipopolysaccharide activates microglia via neuraminidase 1 desialylation of Toll‐like Receptor 4

(2020) David Hans Allendorf et al.   JOURNAL OF NEUROCHEMISTRY

Sialylation and Galectin-3 in Microglia-Mediated Neuroinflammation and Neurodegeneration

(2020) Mar Puigdellívol et al.   Frontiers in Cellular Neuroscience

Sialylation acts as a checkpoint for innate immune responses in the central nervous system

(2020) Christine Klaus et al.   GLIA

Lysosomal Exocytosis: The Extracellular Role of an Intracellular Organelle

(2020) Brunella Tancini et al.   Membranes

Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer’s disease

(2019) Antonio Boza-Serrano et al.   ACTA NEUROPATHOLOGICA

Activated microglia desialylate their surface, stimulating complement receptor 3‐mediated phagocytosis of neurons

(2019) David H. Allendorf et al.   GLIA

Inflammation leads to distinct populations of extracellular vesicles from microglia

(2018) Yiyi Yang et al.   Journal of Neuroinflammation

Keeping it trim: roles of neuraminidases in CNS function

(2018) Alexey V. Pshezhetsky et al.   GLYCOCONJUGATE JOURNAL

Neurophagy, the phagocytosis of live neurons and synapses by glia, contributes to brain development and disease

(2017) Anna Vilalta et al.   FEBS Journal

Rapid regulation of sialidase activity in response to neural activity and sialic acid removal during memory processing in rat hippocampus

(2017) Akira Minami et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activated Microglia Desialylate and Phagocytose Cells via Neuraminidase, Galectin-3, and Mer Tyrosine Kinase

(2017) Koji Nomura et al.   JOURNAL OF IMMUNOLOGY

Rapid Trimming of Cell Surface Polysialic Acid (PolySia) by Exovesicular Sialidase Triggers Release of Preexisting Surface Neurotrophin

(2015) Mizuki Sumida et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rotenone induces neuronal death by microglial phagocytosis of neurons

(2013) Julius V. Emmrich et al.   FEBS Journal

Lactadherin/MFG-E8 is essential for microglia-mediated neuronal loss and phagoptosis induced by amyloid β

(2013) Urte Neniskyte et al.   JOURNAL OF NEUROCHEMISTRY

Depletion of polysialic acid from neural cell adhesion molecule (PSA-NCAM) increases CA3 dendritic arborization and increases vulnerability to excitotoxicity

(2012) Trudy McCall et al.   EXPERIMENTAL NEUROLOGY

Desialylation accelerates platelet clearance after refrigeration and initiates GPIb  metalloproteinase-mediated cleavage in mice

(2011) A. J. G. Jansen et al.   BLOOD

Inhibition of Microglial Phagocytosis Is Sufficient To Prevent Inflammatory Neuronal Death

(2011) J. J. Neher et al.   JOURNAL OF IMMUNOLOGY