Adenosine signaling activates ATP-sensitive K + channels in endothelial cells and pericytes in CNS capillaries

Precapillary sphincters and pericytes at first-order capillaries as key regulators for brain capillary perfusion

(2021) Stefan Andreas Zambach et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATP sensitive potassium (KATP) channel inhibition: A promising new drug target for migraine

(2020) Sarah L Christensen et al.   CEPHALALGIA

Reducing Hypermuscularization of the Transitional Segment between Arterioles and Capillaries Protects Against Spontaneous Intracerebral Hemorrhage

(2020) Julien Ratelade et al.   CIRCULATION

ATP- and voltage-dependent electro-metabolic signaling regulates blood flow in heart

(2020) Guiling Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The pericyte connectome: spatial precision of neurovascular coupling is driven by selective connectivity maps of pericytes and endothelial cells and is disrupted in diabetes

(2020) Tamas Kovacs-Oller et al.   Cell Discovery

Contractile pericytes determine the direction of blood flow at capillary junctions

(2020) Albert L. Gonzales et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Calcitonin Gene‐Related Peptide Modulators – The History and Renaissance of a New Migraine Drug Class

(2019) Richard Hargreaves et al.   HEADACHE

Opening of ATP-sensitive potassium channels causes migraine attacks: a new target for the treatment of migraine

(2019) Mohammad Al-Mahdi Al-Karagholi et al.   BRAIN

CGRP as the target of new migraine therapies — successful translation from bench to clinic

(2018) Lars Edvinsson et al.   Nature Reviews Neurology

Pericyte Structural Remodeling in Cerebrovascular Health and Homeostasis

(2018) Andrée-Anne Berthiaume et al.   Frontiers in Aging Neuroscience

A molecular atlas of cell types and zonation in the brain vasculature

(2018) Michael Vanlandewijck et al.   NATURE

Transcriptional and epigenomic landscapes of CNS and non-CNS vascular endothelial cells

(2018) Mark F Sabbagh et al.   eLife

PIP2 depletion promotes TRPV4 channel activity in mouse brain capillary endothelial cells

(2018) Osama F Harraz et al.   eLife

Capillary K+-sensing initiates retrograde hyperpolarization to increase local cerebral blood flow

(2017) Thomas A Longden et al.   NATURE NEUROSCIENCE

The capillary bed offers the largest hemodynamic resistance to the cortical blood supply

(2016) Ian Gopal Gould et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Inhibition of Myogenic Tone in Rat Cremaster and Cerebral Arteries by SKA-31, an Activator of Endothelial KCa2.3 and KCa3.1 Channels

(2015) Ramesh C. Mishra et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Hypotension Due to Kir6.1 Gain‐of‐Function in Vascular Smooth Muscle

(2013) Anlong Li et al.   Journal of the American Heart Association

Acidosis Dilates Brain Parenchymal Arterioles by Conversion of Calcium Waves to Sparks to Activate BK Channels

(2011) Fabrice Dabertrand et al.   CIRCULATION RESEARCH

Adenosine receptors as drug targets

(2010) Bertil B. Fredholm   EXPERIMENTAL CELL RESEARCH

Glial and neuronal control of brain blood flow

(2010) David Attwell et al.   NATURE

Astrocytic endfoot Ca2+ and BK channels determine both arteriolar dilation and constriction

(2010) Hélène Girouard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA