Pro- and anti-fibrotic effects of vascular endothelial growth factor in chronic kidney diseases

METTL14-regulated PI3K/Akt signaling pathway via PTEN affects HDAC5-mediated epithelial–mesenchymal transition of renal tubular cells in diabetic kidney disease

(2021) Zhaoxia Xu et al.   Cell Death & Disease

Nephrotoxicity of Anti-Angiogenic Therapies

(2021) Margaux Van Wynsberghe et al.   Diagnostics

VEGF-VEGFR2 inhibitor-associated hyaline occlusive glomerular microangiopathy: a Japanese single-center experience

(2021) Masatoyo Ozawa et al.   Clinical and Experimental Nephrology

Nitric oxide signalling in kidney regulation and cardiometabolic health

(2021) Mattias Carlström   Nature Reviews Nephrology

Mild Hypoxia Enhances the Expression of HIF and VEGF and Triggers the Response to Injury in Rat Kidneys

(2021) Yaya Xu et al.   Frontiers in Physiology

Neonatal hyperoxia: effects on nephrogenesis and the key role of klotho as an antioxidant factor

(2020) Lucas Ferreira de Almeida et al.   Journal of Maternal-Fetal & Neonatal Medicine

Human umbilical cord-derived mesenchymal stem cells prevent the progression of early diabetic nephropathy through inhibiting inflammation and fibrosis

(2020) E Xiang et al.   Stem Cell Research & Therapy

The endoplasmic reticulum stress and the unfolded protein response in kidney disease: Implications for vascular growth factors

(2020) Carlo Alberto Ricciardi et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Inhibition of lymphatic proliferation by the selective VEGFR-3 inhibitor SAR131675 ameliorates diabetic nephropathy in db/db mice

(2019) Seun Deuk Hwang et al.   Cell Death & Disease

VEGF Antagonism Attenuates Cerebral Ischemia/Reperfusion-Induced Injury via Inhibiting Endoplasmic Reticulum Stress-Mediated Apoptosis

(2019) Shu-Qing Feng et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

A single number for advocacy and communication—worldwide more than 850 million individuals have kidney diseases

(2019) Kitty J. Jager et al.   KIDNEY INTERNATIONAL

Calcium Dobesilate Restores Autophagy by Inhibiting the VEGF/PI3K/AKT/mTOR Signaling Pathway

(2019) Yue Wang et al.   Frontiers in Pharmacology

Targeted VEGF (Vascular Endothelial Growth Factor) Therapy Induces Long-Term Renal Recovery in Chronic Kidney Disease via Macrophage Polarization

(2019) Jason E. Engel et al.   HYPERTENSION

Endoplasmic reticulum stress in ischemic and nephrotoxic acute kidney injury

(2018) Mingjuan Yan et al.   ANNALS OF MEDICINE

VEGFR (Vascular Endothelial Growth Factor Receptor) Inhibition Induces Cardiovascular Damage via Redox-Sensitive ProcessesNovelty and Significance

(2018) Karla B. Neves et al.   HYPERTENSION

Gremlin Regulates Tubular Epithelial to Mesenchymal Transition via VEGFR2: Potential Role in Renal Fibrosis

(2018) Laura Marquez-Exposito et al.   Frontiers in Pharmacology

Vascular Endothelial Growth Factor Augments Arginine Transport and Nitric Oxide Generation via a KDR Receptor Signaling Pathway

(2017) Moshe Shashar et al.   KIDNEY & BLOOD PRESSURE RESEARCH

Progression of chronic kidney disease: too much cellular talk causes damage

(2017) Leslie Gewin et al.   KIDNEY INTERNATIONAL

Vascular endothelial growth factor-C ameliorates renal interstitial fibrosis through lymphangiogenesis in mouse unilateral ureteral obstruction

(2017) Shoko Hasegawa et al.   LABORATORY INVESTIGATION

Effects of bevacizumab on endoplasmic reticulum stress in hypoxic retinal pigment epithelial cells

(2017) Joo-Hee Park et al.   PLoS One

Restored nitric oxide bioavailability reduces the severity of acute-to-chronic transition in a mouse model of aristolochic acid nephropathy

(2017) Inès Jadot et al.   PLoS One

Selective Stimulation of Cardiac Lymphangiogenesis Reduces Myocardial Edema and Fibrosis Leading to Improved Cardiac Function Following Myocardial InfarctionCLINICAL PERSPECTIVE

(2016) Orianne Henri et al.   CIRCULATION

The origin of renal fibroblasts/myofibroblasts and the signals that trigger fibrosis

(2016) Yu Bo Yang Sun et al.   DIFFERENTIATION

Nitric Oxide Mediates Bleomycin-induced Angiogenesis and Pulmonary Fibrosis via Regulation of VEGF

(2015) Anand Krishnan V. Iyer et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Worldwide access to treatment for end-stage kidney disease: a systematic review

(2015) Thaminda Liyanage et al.   LANCET

RTN1 mediates progression of kidney disease by inducing ER stress

(2015) Ying Fan et al.   Nature Communications

Podocyte-Specific VEGF-A Gain of Function Induces Nodular Glomerulosclerosis in eNOS Null Mice

(2014) D. Veron et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Tubulovascular Cross-Talk by Vascular Endothelial Growth Factor A Maintains Peritubular Microvasculature in Kidney

(2014) H. Dimke et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

VEGF Signals through ATF6 and PERK to Promote Endothelial Cell Survival and Angiogenesis in the Absence of ER Stress

(2014) Evdoxia Karali et al.   MOLECULAR CELL

Nitric oxide donors rescue diabetic nephropathy through oxidative-stress- and nitrosative-stress-mediated Wnt signaling pathways

(2014) Yung-Chien Hsu et al.   Journal of Diabetes Investigation

Stressed to death – mechanisms of ER stress-induced cell death

(2013) Natalia Sovolyova et al.   BIOLOGICAL CHEMISTRY

VEGF suppresses epithelial-mesenchymal transition by inhibiting the expression of Smad3 and miR-192, a Smad3-dependent microRNA

(2013) JUN-PING HONG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

The cyclic GMP–dependent protein kinase Iα suppresses kidney fibrosis

(2013) Elisabeth Schinner et al.   KIDNEY INTERNATIONAL

Peritubular capillary rarefaction: a new therapeutic target in chronic kidney disease

(2013) Yujiro Kida et al.   PEDIATRIC NEPHROLOGY

Renal interstitial fibrosis

(2012) Alton B. Farris et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Vegfa Protects the Glomerular Microvasculature in Diabetes

(2012) G. A. Sivaskandarajah et al.   DIABETES

The Unfolded Protein Response Regulates an Angiogenic Response by the Kidney Epithelium during Ischemic Stress

(2012) Nicolas Bouvier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of nitric oxide on renal interstitial fibrosis in rats with unilateral ureteral obstruction

(2012) Dong Sun et al.   LIFE SCIENCES

VEGF ameliorates tubulointerstitial fibrosis in unilateral ureteral obstruction mice via inhibition of epithelial-mesenchymal transition

(2011) Yao-guo Lian et al.   ACTA PHARMACOLOGICA SINICA

Targeting Endothelium-Pericyte Cross Talk by Inhibiting VEGF Receptor Signaling Attenuates Kidney Microvascular Rarefaction and Fibrosis

(2011) Shuei-Liong Lin et al.   AMERICAN JOURNAL OF PATHOLOGY

Pivotal role of pericytes in kidney fibrosis

(2011) Yujiro Kida et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Podocyte vascular endothelial growth factor (Vegf 164 ) overexpression causes severe nodular glomerulosclerosis in a mouse model of type 1 diabetes

(2011) D. Veron et al.   DIABETOLOGIA

Unknown

(2011) Chih-Kang Chiang et al.   MOLECULAR MEDICINE

Capillary rarefaction, hypoxia, VEGF and angiogenesis in chronic renal disease

(2011) G. Mayer   NEPHROLOGY DIALYSIS TRANSPLANTATION

Hypertension Induced by the Tyrosine Kinase Inhibitor Sunitinib Is Associated With Increased Circulating Endothelin-1 Levels

(2010) Mariëtte H.W. Kappers et al.   HYPERTENSION

Glomerular Structure and Function Require Paracrine, Not Autocrine, VEGF-VEGFR-2 Signaling

(2010) K. Sison et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Autocrine VEGF-VEGF-R loop on podocytes during glomerulonephritis in humans

(2010) B. Hohenstein et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Effects of a cGMP-Specific Phosphodiesterase Inhibitor on Expression of Endothelial Nitric Oxide Synthase and Vascular Endothelial Growth Factor in Rats with Cyclosporine-Induced Nephrotoxicity

(2010) J.W. Yang et al.   TRANSPLANTATION PROCEEDINGS

Inhibition of VEGF or TGF-β Signaling Activates Endothelium and Increases Leukocyte Rolling

(2009) Tony E. Walshe et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Vascular Endothelial Growth Factor Inhibition by dRK6 Causes Endothelial Apoptosis, Fibrosis, and Inflammation in the Heart via the Akt/eNOS Axis in db/db Mice

(2009) C. Whee Park et al.   DIABETES

VEGF signalling inhibition-induced proteinuria: Mechanisms, significance and management

(2009) Hassane Izzedine et al.   EUROPEAN JOURNAL OF CANCER

Salidroside protects cardiomyocyte against hypoxia-induced death: A HIF-1α-activated and VEGF-mediated pathway

(2009) Jinping Zhang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Parathyroid Hormone-Related Protein Promotes Epithelial-Mesenchymal Transition

(2009) J. A. Ardura et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Hypoxia response and VEGF-A expression in human proximal tubular epithelial cells in stable and progressive renal disease

(2009) Michael Rudnicki et al.   LABORATORY INVESTIGATION

Role of renal microcirculation in experimental renovascular disease

(2009) R. Iliescu et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

ATF4-dependent transcription is a key mechanism in VEGF up-regulation by oxidized phospholipids: critical role of oxidized sn-2 residues in activation of unfolded protein response

(2008) O. V. Oskolkova et al.   BLOOD

How Do Mesangial and Endothelial Cells Form the Glomerular Tuft?

(2008) M. R. Vaughan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Inhibition of VEGF blocks TGF- 1 production through a PI3K/Akt signalling pathway

(2007) K. S. Lee et al.   EUROPEAN RESPIRATORY JOURNAL