Mild Hypoxia Enhances the Expression of HIF and VEGF and Triggers the Response to Injury in Rat Kidneys

A novel gastroprotective effect of zeaxanthin against stress-induced gastritis in male rats targeting the expression of HIF-1α, TFF-1 and MMP-9 through PI3K/Akt/JNK signaling pathway

(2021) Mona G. Elhadidy et al.   LIFE SCIENCES

Inhibition of Histone H3K27 Acetylation Orchestrates Interleukin-9-Mediated and Plays an Anti-Inflammatory Role in Cisplatin-Induced Acute Kidney Injury

(2020) Wenjuan Jiang et al.   Frontiers in Immunology

Treatment of Type II Collagen-Induced Rat Rheumatoid Arthritis Model by Interleukin 10 (IL10)-Mesenchymal Stem Cells (BMSCs)

(2019) Shuai Tian et al.   MEDICAL SCIENCE MONITOR

In chronic hypoxia, glucose availability and hypoxic severity dictate the balance between HIF-1 and HIF-2 in astrocytes

(2019) Min Guo et al.   FASEB JOURNAL

Aging‐related carcinoembryonic antigen‐related cell adhesion molecule 1 signaling promotes vascular dysfunction

(2019) Florian Kleefeldt et al.   AGING CELL

Imbalance of Pro- and Anti-Angiogenic Factors Due to Maternal Vitamin D Deficiency Causes Renal Microvasculature Alterations Affecting the Adult Kidney Function

(2019) Lucas Ferreira de Almeida et al.   Nutrients

Advances in Hypoxia-Inducible Factor Biology

(2018) Hani Choudhry et al.   Cell Metabolism

Hypoxia‑induced expression of CXCR4 favors trophoblast cell migration and invasion via the activation of HIF‑1α

(2018) Zhan Zhang et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Systemic biopolymer-delivered vascular endothelial growth factor promotes therapeutic angiogenesis in experimental renovascular disease

(2018) Alejandro R. Chade et al.   KIDNEY INTERNATIONAL

Inhibition of mitochondrial respiration under hypoxia and increased antioxidant activity after reoxygenation of Tribolium castaneum

(2018) Lei Wang et al.   PLoS One

Acetyl-11-keto-β-boswellic acid ameliorates renal interstitial fibrosis via Klotho/TGF-β/Smad signalling pathway

(2018) Minna Liu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Hypoxia-inducible factor prolyl-4-hydroxylation in FOXD1 lineage cells is essential for normal kidney development

(2017) Hanako Kobayashi et al.   KIDNEY INTERNATIONAL

Systems biology of oxygen homeostasis

(2017) Debangshu Samanta et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Endothelial sirtuin 1 inactivation enhances capillary rarefaction and fibrosis following kidney injury through Notch activation

(2016) Yujiro Kida et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Endothelin Receptor Down-Regulation Mediated Ligand Regulation Mechanisms Protect Against Cellular Hypoxia Injury in Rat Vascular Endothelial Cells

(2016) Long Li et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Therapeutic angiogenesis by vascular endothelial growth factor supplementation for treatment of renal disease

(2016) Omar C. Logue et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Similar Hemoglobin Mass Response in Hypobaric and Normobaric Hypoxia in Athletes

(2016) ANNA HAUSER et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Neuroprotective Effects of Ginkgolide B Against Ischemic Stroke: A Review of Current Literature

(2015) Seyed Nabavi et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Podocytes protect glomerular endothelial cells from hypoxic injury via deSUMOylation of HIF-1α signaling

(2015) Lingyu Wang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Hypoxia-Inducible Factor-1: A Critical Player in the Survival Strategy of Stressed Cells

(2015) Shuyang Chen et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Chlorogenic acid inhibits hypoxia-induced angiogenesis via down-regulation of the HIF-1α/AKT pathway

(2015) Jin Ju Park et al.   CELLULAR ONCOLOGY

Oxygen Sensing, Hypoxia-Inducible Factors, and Disease Pathophysiology

(2013) Gregg L. Semenza   Annual Review of Pathology-Mechanisms of Disease

Regulation of the HIF-system in human macrophages – Differential regulation of HIF-α subunits under sustained hypoxia

(2013) David M. Poitz et al.   MOLECULAR IMMUNOLOGY

Renal function and injury in infants and young children with congenital heart disease

(2012) Jianyong Zheng et al.   PEDIATRIC NEPHROLOGY

Topical Insulin Accelerates Wound Healing in Diabetes by Enhancing the AKT and ERK Pathways: A Double-Blind Placebo-Controlled Clinical Trial

(2012) Maria H. M. Lima et al.   PLoS One

Silencing of Hypoxia-Inducible Factor-1α Gene Attenuated Angiotensin II–Induced Renal Injury in Sprague-Dawley Rats

(2011) Qing Zhu et al.   HYPERTENSION

Hypoxia-Inducible Factors and the Response to Hypoxic Stress

(2010) Amar J. Majmundar et al.   MOLECULAR CELL

Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury

(2010) Li Yang et al.   NATURE MEDICINE

HIF in Kidney Disease and Development

(2009) L. Gunaratnam et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Phosphatidylinositol 3,4,5-Triphosphate-Dependent Rac Exchanger 1 (P-Rex-1), a Guanine Nucleotide Exchange Factor for Rac, Mediates Angiogenic Responses to Stromal Cell-Derived Factor-1/Chemokine Stromal Cell Derived Factor-1 (SDF-1/CXCL-12) Linked to Rac Activation, Endothelial Cell Migration, and in Vitro Angiogenesis

(2009) J. Carretero-Ortega et al.   MOLECULAR PHARMACOLOGY

VEGF-B inhibits apoptosis via VEGFR-1–mediated suppression of the expression of BH3-only protein genes in mice and rats

(2008) Yang Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Chronic hypoxia as a mechanism of progression of chronic kidney diseases: from hypothesis to novel therapeutics

(2008) Leon G. Fine et al.   KIDNEY INTERNATIONAL