Effects of the 5-HT2A receptor antagonist volinanserin on head-twitch response and intracranial self-stimulation depression induced by different structural classes of psychedelics in rodents

Psychedelic-inspired drug discovery using an engineered biosensor

(2021) Chunyang Dong et al.   CELL

Trial of Psilocybin versus Escitalopram for Depression

(2021) Robin Carhart-Harris et al.   NEW ENGLAND JOURNAL OF MEDICINE

Harnessing psilocybin: antidepressant-like behavioral and synaptic actions of psilocybin are independent of 5-HT2R activation in mice

(2021) Natalie Hesselgrave et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Psilocybin induces rapid and persistent growth of dendritic spines in frontal cortex in vivo

(2021) Ling-Xiao Shao et al.   NEURON

Sex-specific effects of psychedelics on prepulse inhibition of startle in 129S6/SvEv mice

(2021) Hiba Z. Vohra et al.   PSYCHOPHARMACOLOGY

Role of the 5-HT2A Receptor in Acute Effects of LSD on Empathy and Circulating Oxytocin

(2021) Friederike Holze et al.   Frontiers in Pharmacology

Prolonged epigenomic and synaptic plasticity alterations following single exposure to a psychedelic in mice

(2021) Mario de la Fuente Revenga et al.   Cell Reports

Automated quantification of head-twitch response in mice via ear tag reporter coupled with biphasic detection

(2020) Mario de la Fuente Revenga et al.   JOURNAL OF NEUROSCIENCE METHODS

Kappa opioid agonists reduce oxycodone self-administration in male rhesus monkeys

(2020) C. Austin Zamarripa et al.   PSYCHOPHARMACOLOGY

Investigation of the Optical Isomers of Methcathinone, and Two Achiral Analogs, at Monoamine Transporters and in Intracranial Self-Stimulation Studies in Rats

(2020) Rachel A. Davies et al.   ACS Chemical Neuroscience

Correlation between the potency of hallucinogens in the mouse head-twitch response assay and their behavioral and subjective effects in other species

(2020) Adam L. Halberstadt et al.   NEUROPHARMACOLOGY

Automated detection of the head-twitch response using wavelet scalograms and a deep convolutional neural network

(2020) Adam L. Halberstadt   Scientific Reports

A non-hallucinogenic psychedelic analogue with therapeutic potential

(2020) Lindsay P. Cameron et al.   NATURE

Investigating the role of 5-HT2A and 5-HT2C receptor activation in the effects of psilocybin, DOI, and citalopram on marble burying in mice

(2020) Anna U. Odland et al.   BEHAVIOURAL BRAIN RESEARCH

Effects of acute and repeated treatment with serotonin 5-HT2A receptor agonist hallucinogens on intracranial self-stimulation in rats.

(2019) Farhana Sakloth et al.   EXPERIMENTAL AND CLINICAL PSYCHOPHARMACOLOGY

Interactions between pain states and opioid reward assessed with intracranial self-stimulation in rats

(2019) Megan J. Moerke et al.   NEUROPHARMACOLOGY

Effects of the synthetic psychedelic 2,5-dimethoxy-4-iodoamphetamine (DOI) on ethanol consumption and place conditioning in male mice

(2019) Aboagyewaah Oppong-Damoah et al.   PSYCHOPHARMACOLOGY

Fully automated head-twitch detection system for the study of 5-HT2A receptor pharmacology in vivo

(2019) Mario de la Fuente Revenga et al.   Scientific Reports

Psychedelics Promote Structural and Functional Neural Plasticity

(2018) Calvin Ly et al.   Cell Reports

LSD Administered as a Single Dose Reduces Alcohol Consumption in C57BL/6J Mice

(2018) Kenneth Alper et al.   Frontiers in Pharmacology

Changes in global and thalamic brain connectivity in LSD-induced altered states of consciousness are attributable to the 5-HT2A receptor

(2018) Katrin H Preller et al.   eLife

The mechanism of acute fasting-induced antidepressant-like effects in mice

(2017) Ranji Cui et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Opposing effects of dopamine D1- and D2-like agonists on intracranial self-stimulation in male rats.

(2016) Matthew F. Lazenka et al.   EXPERIMENTAL AND CLINICAL PSYCHOPHARMACOLOGY

Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial

(2016) Roland R Griffiths et al.   JOURNAL OF PSYCHOPHARMACOLOGY

The hallucinogen d -lysergic diethylamide (LSD) decreases dopamine firing activity through 5-HT 1A , D 2 and TAAR 1 receptors

(2016) Danilo De Gregorio et al.   PHARMACOLOGICAL RESEARCH

Long-term follow-up of psilocybin-facilitated smoking cessation

(2016) Matthew W. Johnson et al.   AMERICAN JOURNAL OF DRUG AND ALCOHOL ABUSE

Acute Effects of Lysergic Acid Diethylamide in Healthy Subjects

(2015) Yasmin Schmid et al.   BIOLOGICAL PSYCHIATRY

Psilocybin-assisted treatment for alcohol dependence: A proof-of-concept study

(2015) Michael P Bogenschutz et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Safety and Efficacy of Lysergic Acid Diethylamide-Assisted Psychotherapy for Anxiety Associated With Life-threatening Diseases

(2014) Peter Gasser et al.   JOURNAL OF NERVOUS AND MENTAL DISEASE

Pilot study of the 5-HT2AR agonist psilocybin in the treatment of tobacco addiction

(2014) Matthew W Johnson et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Pharmacological activity of Salvinorin A, the major component of Salvia divinorum

(2014) Joanna Listos et al.   Pharmacological Reports

Hallucinogenic 5-HT2AR agonists LSD and DOI enhance dopamine D2R protomer recognition and signaling of D2-5-HT2A heteroreceptor complexes

(2013) Dasiel O. Borroto-Escuela et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Activation of Serotonin 2A Receptors Underlies the Psilocybin-Induced Effects on   Oscillations, N170 Visual-Evoked Potentials, and Visual Hallucinations

(2013) M. Kometer et al.   JOURNAL OF NEUROSCIENCE

Effects of the hallucinogen 2,5-dimethoxy-4-iodophenethylamine (2C-I) and superpotent N-benzyl derivatives on the head twitch response

(2013) Adam L. Halberstadt et al.   NEUROPHARMACOLOGY

Animal Models of Serotonergic Psychedelics

(2012) James B. Hanks et al.   ACS Chemical Neuroscience

Lysergic acid diethylamide (LSD) for alcoholism: meta-analysis of randomized controlled trials

(2012) Teri S Krebs et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Repeated Exposure to the κ-Opioid Receptor Agonist Salvinorin A Modulates Extracellular Signal-Regulated Kinase and Reward Sensitivity

(2011) David N. Potter et al.   BIOLOGICAL PSYCHIATRY

Multiple receptors contribute to the behavioral effects of indoleamine hallucinogens

(2011) Adam L. Halberstadt et al.   NEUROPHARMACOLOGY

Serotonergic and dopaminergic distinctions in the behavioral pharmacology of (±)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD)

(2011) Emmanuelle A.D. Schindler et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Interaction of 5-HT2A and 5-HT2C Receptors in R(-)-2,5-Dimethoxy-4-iodoamphetamine-Elicited Head Twitch Behavior in Mice

(2010) W. E. Fantegrossi et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Depressive-like effects of the kappa opioid receptor agonist salvinorin A are associated with decreased phasic dopamine release in the nucleus accumbens

(2010) Stephanie R. Ebner et al.   PSYCHOPHARMACOLOGY