Prolonged epigenomic and synaptic plasticity alterations following single exposure to a psychedelic in mice

Increased thin-spine density in frontal cortex pyramidal neurons in a genetic rat model of schizophrenia-relevant features

(2021) A. Sánchez-González et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Positive expectations predict improved mental-health outcomes linked to psychedelic microdosing

(2021) L. S. Kaertner et al.   Scientific Reports

Trial of Psilocybin versus Escitalopram for Depression

(2021) Robin Carhart-Harris et al.   NEW ENGLAND JOURNAL OF MEDICINE

Harnessing psilocybin: antidepressant-like behavioral and synaptic actions of psilocybin are independent of 5-HT2R activation in mice

(2021) Natalie Hesselgrave et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Psilocybin induces rapid and persistent growth of dendritic spines in frontal cortex in vivo

(2021) Ling-Xiao Shao et al.   NEURON

Psychedelics, but Not Ketamine, Produce Persistent Antidepressant-like Effects in a Rodent Experimental System for the Study of Depression

(2020) Meghan Hibicke et al.   ACS Chemical Neuroscience

An atlas of dynamic chromatin landscapes in mouse fetal development

(2020) David U. Gorkin et al.   NATURE

A non-hallucinogenic psychedelic analogue with therapeutic potential

(2020) Lindsay P. Cameron et al.   NATURE

A Dendrite-Focused Framework for Understanding the Actions of Ketamine and Psychedelics

(2020) Neil K. Savalia et al.   TRENDS IN NEUROSCIENCES

Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder

(2020) Alan K. Davis et al.   JAMA Psychiatry

(2R,6R)-hydroxynorketamine exerts mGlu2receptor-dependent antidepressant actions

(2019) Panos Zanos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The critical importance of basic animal research for neuropsychiatric disorders

(2019) Tracy L. Bale et al.   NEUROPSYCHOPHARMACOLOGY

White Matter Abnormalities in Major Depression Biotypes Identified by Diffusion Tensor Imaging

(2019) Sugai Liang et al.   Neuroscience Bulletin

Neurobiological functions of transcriptional enhancers

(2019) Alex S. Nord et al.   NATURE NEUROSCIENCE

MOWChIP-seq for low-input and multiplexed profiling of genome-wide histone modifications

(2019) Bohan Zhu et al.   Nature Protocols

Fully automated head-twitch detection system for the study of 5-HT2A receptor pharmacology in vivo

(2019) Mario de la Fuente Revenga et al.   Scientific Reports

A Novel Neighbor Housing Environment Enhances Social Interaction and Rescues Cognitive Deficits from Social Isolation in Adolescence

(2019) Alexander B. Pais et al.   Brain Sciences

Oligodendrocyte Neurofascin Independently Regulates Both Myelin Targeting and Sheath Growth in the CNS

(2019) Anna Klingseisen et al.   DEVELOPMENTAL CELL

Neurog2 Deficiency Uncovers a Critical Period of Cell Fate Plasticity and Vulnerability among Neural-Crest-Derived Somatosensory Progenitors

(2019) Stéphanie Ventéo et al.   Cell Reports

Effects of N,N-Dimethyltryptamine on Rat Behaviors Relevant to Anxiety and Depression

(2018) Lindsay P. Cameron et al.   ACS Chemical Neuroscience

HDAC2-dependent Antipsychotic-like Effects of Chronic Treatment with the HDAC Inhibitor SAHA in Mice

(2018) Mario de la Fuente Revenga et al.   NEUROSCIENCE

Psychedelics Promote Structural and Functional Neural Plasticity

(2018) Calvin Ly et al.   Cell Reports

Low-input and multiplexed microfluidic assay reveals epigenomic variation across cerebellum and prefrontal cortex

(2018) Sai Ma et al.   Science Advances

Role of mGlu2 in the 5-HT2A receptor-dependent antipsychotic activity of clozapine in mice

(2018) Kelsey S. Hideshima et al.   PSYCHOPHARMACOLOGY

Antipsychotic-induced Hdac2 transcription via NF-κB leads to synaptic and cognitive side effects

(2017) Daisuke Ibi et al.   NATURE NEUROSCIENCE

Characterisation of CASPR2 deficiency disorder - a syndrome involving autism, epilepsy and language impairment

(2016) Pedro Rodenas-Cuadrado et al.   BMC Medical Genetics

Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial

(2016) Roland R Griffiths et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Dysregulation of the dopamine system in the pathophysiology of schizophrenia and depression

(2016) Anthony A. Grace   NATURE REVIEWS NEUROSCIENCE

Neuronal subtypes and diversity revealed by single-nucleus RNA sequencing of the human brain

(2016) B. B. Lake et al.   SCIENCE

Serotonin 5-HT2 receptor activation prevents allergic asthma in a mouse model

(2015) Felix Nau et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

ChIPseeker: an R/Bioconductor package for ChIP peak annotation, comparison and visualization

(2015) Guangchuang Yu et al.   BIOINFORMATICS

Acute Effects of Lysergic Acid Diethylamide in Healthy Subjects

(2015) Yasmin Schmid et al.   BIOLOGICAL PSYCHIATRY

HISAT: a fast spliced aligner with low memory requirements

(2015) Daehwan Kim et al.   NATURE METHODS

A microfluidic device for epigenomic profiling using 100 cells

(2015) Zhenning Cao et al.   NATURE METHODS

Neuronal circuits for fear and anxiety

(2015) Philip Tovote et al.   NATURE REVIEWS NEUROSCIENCE

Full-length RNA-seq from single cells using Smart-seq2

(2014) Simone Picelli et al.   Nature Protocols

Chronic LSD alters gene expression profiles in the mPFC relevant to schizophrenia

(2014) David A. Martin et al.   NEUROPHARMACOLOGY

The STAR*D Trial: Revealing the Need for Better Treatments

(2014) Thomas R. Insel et al.   PSYCHIATRIC SERVICES

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Smart-seq2 for sensitive full-length transcriptome profiling in single cells

(2013) Simone Picelli et al.   NATURE METHODS

Histone acetylation: molecular mnemonics on the chromatin

(2013) Johannes Gräff et al.   NATURE REVIEWS NEUROSCIENCE

Molecular mechanisms of dendrite stability

(2013) Anthony J. Koleske   NATURE REVIEWS NEUROSCIENCE

Animal Models of Serotonergic Psychedelics

(2012) James B. Hanks et al.   ACS Chemical Neuroscience

Head-twitch response in rodents induced by the hallucinogen 2,5-dimethoxy-4-iodoamphetamine: a comprehensive history, a re-evaluation of mechanisms, and its utility as a model

(2012) Clint E. Canal et al.   Drug Testing and Analysis

Differential oestrogen receptor binding is associated with clinical outcome in breast cancer

(2012) Caryn S. Ross-Innes et al.   NATURE

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

HDAC2 regulates atypical antipsychotic responses through the modulation of mGlu2 promoter activity

(2012) Mitsumasa Kurita et al.   NATURE NEUROSCIENCE

Stimulation of serotonin 2A receptors facilitates consolidation and extinction of fear memory in C57BL/6J mice

(2012) Gongliang Zhang et al.   NEUROPHARMACOLOGY

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Systematic Localization of Common Disease-Associated Variation in Regulatory DNA

(2012) M. T. Maurano et al.   SCIENCE

Synaptic Dysfunction in Depression: Potential Therapeutic Targets

(2012) R. S. Duman et al.   SCIENCE

What does CNTNAP2 reveal about autism spectrum disorder?

(2012) Olga Peñagarikano et al.   TRENDS IN MOLECULAR MEDICINE

Amelioration of hypoxia-induced striatal 5-HT2A receptor, 5-HT transporter and HIF1 alterations by glucose, oxygen and epinephrine in neonatal rats

(2011) T.R. Anju et al.   NEUROSCIENCE LETTERS

BEDTools: a flexible suite of utilities for comparing genomic features

(2010) Aaron R. Quinlan et al.   BIOINFORMATICS

Axon growth and guidance genes identify nascent, immature, and mature olfactory sensory neurons

(2010) Jeremy C. McIntyre et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Hypoxia-Inducible Factors and the Response to Hypoxic Stress

(2010) Amar J. Majmundar et al.   MOLECULAR CELL

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

Psychedelics and the Human Receptorome

(2010) Thomas S. Ray   PLoS One

Histone H3K27ac separates active from poised enhancers and predicts developmental state

(2010) M. P. Creyghton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Essential Role of the Histone Methyltransferase G9a in Cocaine-Induced Plasticity

(2010) I. Maze et al.   SCIENCE

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Rapid modulation of spine morphology by the 5-HT2A serotonin receptor through kalirin-7 signaling

(2009) K. A. Jones et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS

Glial and neuronal isoforms of Neurofascin have distinct roles in the assembly of nodes of Ranvier in the central nervous system

(2008) Barbara Zonta et al.   JOURNAL OF CELL BIOLOGY

Mystical-type experiences occasioned by psilocybin mediate the attribution of personal meaning and spiritual significance 14 months later

(2008) RR Griffiths et al.   JOURNAL OF PSYCHOPHARMACOLOGY

The molecular neurobiology of depression

(2008) Vaishnav Krishnan et al.   NATURE

Pyramidal neurons: dendritic structure and synaptic integration

(2008) Nelson Spruston   NATURE REVIEWS NEUROSCIENCE

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY