SARS-CoV-2 infection of airway cells causes intense viral and cell shedding, two spreading mechanisms affected by IL-13

The Type 2 Asthma Mediator IL-13 Inhibits SARS-CoV-2 Infection of Bronchial Epithelium

(2022) Luke R Bonser et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

An evidence review of face masks against COVID-19

(2021) Jeremy Howard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Implications of preexisting asthma on COVID-19 pathogenesis

(2021) Rakhee K. Ramakrishnan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Functional landscape of SARS-CoV-2 cellular restriction

(2021) Laura Martin-Sancho et al.   MOLECULAR CELL

Treatment of cystic fibrosis airway cells with CFTR modulators reverses aberrant mucus properties via hydration

(2021) Cameron B. Morrison et al.   EUROPEAN RESPIRATORY JOURNAL

Mucociliary Clearance Differs in Mild Asthma by Levels of Type 2 Inflammation

(2021) Timothy E. Corcoran et al.   CHEST

Unique epidemiological and clinical features of the emerging 2019 novel coronavirus pneumonia (COVID‐19) implicate special control measures

(2020) Yixuan Wang et al.   JOURNAL OF MEDICAL VIROLOGY

Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study

(2020) Nanshan Chen et al.   LANCET

A pneumonia outbreak associated with a new coronavirus of probable bat origin

(2020) Peng Zhou et al.   NATURE

A Novel Coronavirus from Patients with Pneumonia in China, 2019

(2020) Na Zhu et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Incubation Period of Coronavirus Disease 2019 (COVID-19) From Publicly Reported Confirmed Cases: Estimation and Application

(2020) Stephen A. Lauer et al.   ANNALS OF INTERNAL MEDICINE

SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract

(2020) Yixuan J. Hou et al.   CELL

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Concerns about COVID-related Collateral Damage for Patients with COPD

(2020) Valerie Press et al.   CHEST

Type 2 Inflammation Modulates ACE2 and TMPRSS2 in Airway Epithelial Cells

(2020) Hiroki Kimura et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Association of respiratory allergy, asthma, and expression of the SARS-CoV-2 receptor ACE2

(2020) Daniel J. Jackson et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes

(2020) Waradon Sungnak et al.   NATURE MEDICINE

A Single-cell Atlas of the Human Healthy Airways

(2020) Marie Deprez et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Association of asthma and its genetic predisposition with the risk of severe COVID-19

(2020) Zhaozhong Zhu et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Prevalence and characterization of asthma in hospitalized and nonhospitalized patients with COVID-19

(2020) Krishan D. Chhiba et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Physical distancing, face masks, and eye protection to prevent person-to-person transmission of SARS-CoV-2 and COVID-19: a systematic review and meta-analysis

(2020) Derek K Chu et al.   LANCET

A Mouse-Adapted SARS-CoV-2 Induces Acute Lung Injury and Mortality in Standard Laboratory Mice

(2020) Sarah R. Leist et al.   CELL

SARS-CoV-2 Infection of Airway Cells

(2020) Camille Ehre   NEW ENGLAND JOURNAL OF MEDICINE

The Possible Dual Role of the ACE2 Receptor in Asthma and Coronavirus (SARS-CoV2) Infection

(2020) Anna Cláudia Calvielli Castelo Branco et al.   Frontiers in Cellular and Infection Microbiology

Secretory Cells Dominate Airway CFTR Expression and Function in Human Airway Superficial Epithelia

(2020) Kenichi Okuda et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

COVID-19 Susceptibility in Bronchial Asthma

(2020) Ilan Green et al.   Journal of Allergy and Clinical Immunology-In Practice

HSP90 inhibitor geldanamycin reverts IL-13– and IL-17–induced airway goblet cell metaplasia

(2019) Alejandro A. Pezzulo et al.   JOURNAL OF CLINICAL INVESTIGATION

A cellular census of human lungs identifies novel cell states in health and in asthma

(2019) Felipe A. Vieira Braga et al.   NATURE MEDICINE

IL-1β dominates the promucin secretory cytokine profile in cystic fibrosis

(2019) Gang Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Mucins: the frontline defence of the lung

(2018) Caroline Ridley et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Vesicle-Cloaked Virus Clusters Are Optimal Units for Inter-organismal Viral Transmission

(2018) Marianita Santiana et al.   Cell Host & Microbe

Airway Mucin Concentration as a Marker of Chronic Bronchitis

(2017) Mehmet Kesimer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Epithelial tethering of MUC5AC-rich mucus impairs mucociliary transport in asthma

(2016) Luke R. Bonser et al.   JOURNAL OF CLINICAL INVESTIGATION

Erratum: Corrigendum: A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence

(2016) Vineet D Menachery et al.   NATURE MEDICINE

SARS-like WIV1-CoV poised for human emergence

(2016) Vineet D. Menachery et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RSV-encoded NS2 promotes epithelial cell shedding and distal airway obstruction

(2014) Rachael M. Liesman et al.   JOURNAL OF CLINICAL INVESTIGATION

Molecular pathology of emerging coronavirus infections

(2014) Lisa E Gralinski et al.   JOURNAL OF PATHOLOGY

Ciliary dyskinesia is an early feature of respiratory syncytial virus infection

(2013) C. M. Smith et al.   EUROPEAN RESPIRATORY JOURNAL

Measures of gene expression in sputum cells can identify TH2-high and TH2-low subtypes of asthma

(2013) Michael C. Peters et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Influenza A Induces the Major Secreted Airway Mucin MUC5AC in a Protease–EGFR–Extracellular Regulated Kinase–Sp1–Dependent Pathway

(2012) Diane Barbier et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

IL-13–induced airway mucus production is attenuated by MAPK13 inhibition

(2012) Yael G. Alevy et al.   JOURNAL OF CLINICAL INVESTIGATION

Molecular organization of the mucins and glycocalyx underlying mucus transport over mucosal surfaces of the airways

(2012) M Kesimer et al.   Mucosal Immunology

Overexpressing mouse model demonstrates the protective role of Muc5ac in the lungs

(2012) C. Ehre et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Periciliary Brush Promotes the Lung Health by Separating the Mucus Layer from Airway Epithelia

(2012) B. Button et al.   SCIENCE

Distinct epithelial gene expression phenotypes in childhood respiratory allergy

(2011) Lisa Giovannini-Chami et al.   EUROPEAN RESPIRATORY JOURNAL

Rhinovirus induces MUC5AC in a human infection model and in vitro via NF- B and EGFR pathways

(2010) C. A. Hewson et al.   EUROPEAN RESPIRATORY JOURNAL

Airway Mucus Function and Dysfunction

(2010) John V. Fahy et al.   NEW ENGLAND JOURNAL OF MEDICINE