IL-13–induced airway mucus production is attenuated by MAPK13 inhibition

TMEM16A Induces MAPK and Contributes Directly to Tumorigenesis and Cancer Progression

(2012) U. Duvvuri et al.   CANCER RESEARCH

p38 MAPK inhibitors, IKK2 inhibitors, and TNFα inhibitors in COPD

(2012) Audreesh Banerjee et al.   CURRENT OPINION IN PHARMACOLOGY

Self-cleavage of Human CLCA1 Protein by a Novel Internal Metalloprotease Domain Controls Calcium-activated Chloride Channel Activation

(2012) Zeynep Yurtsever et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mucin5B expression by lung alveolar macrophages is increased in long-term smokers

(2012) Ruth Sepper et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Impaired autoproteolytic cleavage of mCLCA6, a murine integral membrane protein expressed in enterocytes, leads to cleavage at the plasma membrane instead of the endoplasmic reticulum

(2012) Melanie K. Bothe et al.   MOLECULES AND CELLS

p38  and p38  kinases regulate the Toll-like receptor 4 (TLR4)-induced cytokine production by controlling ERK1/2 protein kinase pathway activation

(2012) A. Risco et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

3-Amino-pyrazolo[3,4-d]pyrimidines as p38α kinase inhibitors: Design and development to a highly selective lead

(2011) Michael Soth et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

p38 Mitogen-Activated Protein Kinase Pathways in Asthma and COPD

(2011) Kian Fan Chung   CHEST

Classification of scaffold-hopping approaches

(2011) Hongmao Sun et al.   DRUG DISCOVERY TODAY

Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases

(2011) M. Cargnello et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

The murine goblet cell protein mCLCA3 is a zinc-dependent metalloprotease with autoproteolytic activity

(2011) Melanie K. Bothe et al.   MOLECULES AND CELLS

Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor

(2011) Solveigh C Koeberle et al.   Nature Chemical Biology

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Mechanisms and functions of p38 MAPK signalling

(2010) Ana Cuadrado et al.   BIOCHEMICAL JOURNAL

X-ray crystal structure of JNK2 complexed with the p38α inhibitor BIRB796: Insights into the rational design of DFG-out binding MAP kinase inhibitors

(2010) Andreas Kuglstatter et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Global Initiative for Chronic Obstructive Lung Disease Stage 0 Is Associated With Excess FEV 1 Decline in a Representative Population Sample

(2010) Roshan Brito-Mutunayagam et al.   CHEST

Effects of IL-13 on Mucociliary Differentiation of Pediatric Asthmatic Bronchial Epithelial Cells

(2010) Surendran Thavagnanam et al.   PEDIATRIC RESEARCH

Regulation of Neuregulin 1β1–Induced MUC5AC and MUC5B Expression in Human Airway Epithelium

(2009) Rachel Kettle et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Cigarette Smoke Induces Nucleic-Acid Oxidation in Lung Fibroblasts

(2009) Gaetan Deslee et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

p38  Mitogen-Activated Protein Kinase Is Essential for Skin Tumor Development in Mice

(2009) E. M. Schindler et al.   CANCER RESEARCH

Regulation of PKD by the MAPK p38δ in Insulin Secretion and Glucose Homeostasis

(2009) Grzegorz Sumara et al.   CELL

Murine mCLCA5 is expressed in granular layer keratinocytes of stratified epithelia

(2009) Josephine Braun et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Selective p38α Inhibitors Clinically Evaluated for the Treatment of Chronic Inflammatory Disorders

(2009) David M. Goldstein et al.   JOURNAL OF MEDICINAL CHEMISTRY

Human ClCa1 modulates anionic conduction of calcium-dependent chloride currents

(2009) Martine Hamann et al.   JOURNAL OF PHYSIOLOGY-LONDON

Sphingosine kinase 1 regulates mucin production via ERK phosphorylation

(2009) Yuko Kono et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

mCLCA4 ER processing and secretion requires luminal sorting motifs

(2008) Chunlei Huan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

MUC5B Is the Major Mucin in the Gel Phase of Sputum in Chronic Obstructive Pulmonary Disease

(2008) Sara Kirkham et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The Role of CLCA Proteins in Inflammatory Airway Disease

(2008) Anand C. Patel et al.   Annual Review of Physiology

Murine mCLCA6 Is an Integral Apical Membrane Protein of Non-goblet Cell Enterocytes and Co-localizes With the Cystic Fibrosis Transmembrane Conductance Regulator

(2008) Melanie K. Bothe et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

A quantitative analysis of kinase inhibitor selectivity

(2008) Mazen W Karaman et al.   NATURE BIOTECHNOLOGY

Persistent activation of an innate immune response translates respiratory viral infection into chronic lung disease

(2008) Edy Y Kim et al.   NATURE MEDICINE

Increased activation of p38 MAPK in COPD

(2007) T. Renda et al.   EUROPEAN RESPIRATORY JOURNAL