A novel strategy for production of liraglutide precursor peptide and development of a new long-acting incretin mimic

Incretin-Based Therapies Role in COVID-19 Era: Evolving Insights

(2020) Anca Pantea Stoian et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

Peak Fitting Applied to Fourier Transform Infrared and Raman Spectroscopic Analysis of Proteins

(2020) Azin Sadat et al.   Applied Sciences-Basel

Synthesis and Statistical Optimization of Poly (Lactic-Co-Glycolic Acid) Nanoparticles Encapsulating GLP1 Analog Designed for Oral Delivery

(2019) Ruba Ismail et al.   PHARMACEUTICAL RESEARCH

The Discovery and Development of Liraglutide and Semaglutide

(2019) Lotte Bjerre Knudsen et al.   Frontiers in Endocrinology

Liraglutide treatment reduced interleukin 6 in adults with type 1 diabetes but did not improve established autonomic or polyneuropathy

(2019) C. Brock et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Structural and functional characterization of D109H and R69C mutant versions of human αB-crystallin: The biochemical pathomechanism underlying cataract and myopathy development

(2019) Maryam Ghahramani et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Glycation of human serum albumin impairs binding to the glucagon-like peptide-1 analogue liraglutide

(2018) Angélique Gajahi Soudahome et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glucagon-like peptide 1 in health and disease

(2018) Andreas Andersen et al.   Nature Reviews Endocrinology

Human αB-crystallin as fusion protein and molecular chaperone increases the expression and folding efficiency of recombinant insulin

(2018) Mohsen Akbarian et al.   PLoS One

Liraglutide pharmacotherapy reduces body weight and improves glycaemic control in juvenile obese/hyperglycaemic male and female rats

(2018) Claudia G. Liberini et al.   DIABETES OBESITY & METABOLISM

A novel strategy to prepare the precursor peptide of liraglutide

(2017) Nian Cheng et al.   PROCESS BIOCHEMISTRY

Innovative chemical synthesis and conformational hints on the lipopeptide liraglutide

(2016) Ivan Guryanov et al.   JOURNAL OF PEPTIDE SCIENCE

Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes

(2016) Steven P. Marso et al.   NEW ENGLAND JOURNAL OF MEDICINE

Expression and Characterization of a Potent Long-Acting GLP-1 Receptor Agonist, GLP-1-IgG2σ-Fc

(2016) Yi Yang et al.   PLoS One

Incretin mimetics: a novel therapeutic option for patients with type 2 diabetes – a review

(2016) Filip Krag Knop et al.   Diabetes Metabolic Syndrome and Obesity-Targets and Therapy

Concomitant Raman spectroscopy and dynamic light scattering for characterization of therapeutic proteins at high concentrations

(2015) Chen Zhou et al.   ANALYTICAL BIOCHEMISTRY

Transformation of Oligomers of Lipidated Peptide Induced by Change in pH

(2015) Ying Wang et al.   MOLECULAR PHARMACEUTICS

Physiology of Proglucagon Peptides: Role of Glucagon and GLP-1 in Health and Disease

(2015) Darleen A. Sandoval et al.   PHYSIOLOGICAL REVIEWS

Type 2 diabetes mellitus

(2015) Ralph A. DeFronzo et al.   Nature Reviews Disease Primers

Liraglutide Improves Pancreatic Beta Cell Mass and Function in Alloxan-Induced Diabetic Mice

(2015) Kanako Tamura et al.   PLoS One

A strategy for fusion expression and preparation of functional glucagon-like peptide-1 (GLP-1) analogue by introducing an enterokinase cleavage site

(2014) Yang Liu et al.   BIOTECHNOLOGY LETTERS

One size does not fit all: The oligomeric states of αB crystallin

(2013) Scott P. Delbecq et al.   FEBS LETTERS

GLP-1 receptor activation and Epac2 link atrial natriuretic peptide secretion to control of blood pressure

(2013) Minsuk Kim et al.   NATURE MEDICINE

Effects of exenatide and liraglutide on heart rate, blood pressure and body weight: systematic review and meta-analysis

(2013) Louise E Robinson et al.   BMJ Open

Liraglutide: short-lived effect on gastric emptying-long lasting effects on body weight

(2012) J. Jelsing et al.   DIABETES OBESITY & METABOLISM

The structure and function of the glucagon-like peptide-1 receptor and its ligands

(2011) Dan Donnelly   BRITISH JOURNAL OF PHARMACOLOGY

The Diabetes Drug Liraglutide Prevents Degenerative Processes in a Mouse Model of Alzheimer's Disease

(2011) P. L. McClean et al.   JOURNAL OF NEUROSCIENCE

Cyanogen bromide cleavage of proteins in salt and buffer solutions

(2010) Yaroslav A. Andreev et al.   ANALYTICAL BIOCHEMISTRY

Liraglutide: the therapeutic promise from animal models

(2010) L. B. Knudsen   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

Protein characterisation by synchrotron radiation circular dichroism spectroscopy

(2010) B. A. Wallace   QUARTERLY REVIEWS OF BIOPHYSICS

Raman spectra of amino acids and their aqueous solutions

(2010) Guangyong Zhu et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

Lens aging: Effects of crystallins

(2009) K. Krishna Sharma et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Development, Characterization, and Evaluation of a Fusion Protein of a Novel Glucagon-Like Peptide-1 (GLP-1) Analog and Human Serum Albumin inPichia pastoris

(2009) Zhihui GAO et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Crystal Structure of Glucagon-like Peptide-1 in Complex with the Extracellular Domain of the Glucagon-like Peptide-1 Receptor

(2009) Christina Rye Underwood et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evaluating the glucose tolerance test in mice

(2008) Sofianos Andrikopoulos et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Extrinsic Fluorescent Dyes as Tools for Protein Characterization

(2008) Andrea Hawe et al.   PHARMACEUTICAL RESEARCH

Interactions of Hydrophobin Proteins in Solution Studied by Small-Angle X-Ray Scattering

(2007) Kaisa Kisko et al.   BIOPHYSICAL JOURNAL