Plant‐based expression and characterization of SARS‐CoV‐2 virus‐like particles presenting a native spike protein

SARS-CoV-2 spike glycoprotein vaccine candidate NVX-CoV2373 immunogenicity in baboons and protection in mice

(2021) Jing-Hui Tian et al.   Nature Communications

Phase 1 randomized trial of a plant-derived virus-like particle vaccine for COVID-19

(2021) Brian J. Ward et al.   NATURE MEDICINE

Plant‐based production can result in covalent cross‐linking of proteins

(2021) Roger Castells‐Graells et al.   PLANT BIOTECHNOLOGY JOURNAL

Interactions of SARS-CoV-2 envelope protein with amilorides correlate with antiviral activity

(2021) Sang Ho Park et al.   PLoS Pathogens

SARS-CoV-2 Vaccines Based on the Spike Glycoprotein and Implications of New Viral Variants

(2021) Daniel Martínez-Flores et al.   Frontiers in Immunology

Development and Optimization of an Enzyme Immunoassay to Detect Serum Antibodies against the Hepatitis E Virus in Pigs, Using Plant-Derived ORF2 Recombinant Protein

(2021) Katerina Takova et al.   Vaccines

Producing Vaccines against Enveloped Viruses in Plants: Making the Impossible, Difficult

(2021) Hadrien Peyret et al.   Vaccines

Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding

(2020) Roujian Lu et al.   LANCET

Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses

(2020) Michael Letko et al.   Nature Microbiology

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

(2020) Alexandra C. Walls et al.   CELL

Cell entry mechanisms of SARS-CoV-2

(2020) Jian Shang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural and functional properties of SARS-CoV-2 spike protein: potential antivirus drug development for COVID-19

(2020) Yuan Huang et al.   ACTA PHARMACOLOGICA SINICA

Emerging coronaviruses: Genome structure, replication, and pathogenesis

(2020) Yu Chen et al.   JOURNAL OF MEDICAL VIROLOGY

Structure of Furin Protease Binding to SARS-CoV-2 Spike Glycoprotein and Implications for Potential Targets and Virulence

(2020) Naveen Vankadari   Journal of Physical Chemistry Letters

Safety and Immunogenicity of Two RNA-Based Covid-19 Vaccine Candidates

(2020) Edward E. Walsh et al.   NEW ENGLAND JOURNAL OF MEDICINE

Plant‐made dengue virus‐like particles produced by co‐expression of structural and non‐structural proteins induce a humoral immune response in mice

(2020) Daniel Ponndorf et al.   PLANT BIOTECHNOLOGY JOURNAL

Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine

(2020) Fernando P. Polack et al.   NEW ENGLAND JOURNAL OF MEDICINE

Highly sensitive and specific graphene/TiO2 impedimetric immunosensor based on plant-derived tetravalent envelope glycoprotein domain III (EDIII) probe antigen for dengue diagnosis

(2020) Qi Yan Siew et al.   BIOSENSORS & BIOELECTRONICS

Epitope Presentation of Dengue Viral Envelope Glycoprotein Domain III on Hepatitis B Core Protein Virus-Like Particles Produced in Nicotiana benthamiana

(2019) Ee Leen Pang et al.   Frontiers in Plant Science

Post-translational modifications of coronavirus proteins: roles and function

(2018) To Sing Fung et al.   Future Virology

Immunogenicity of an S1D epitope from porcine epidemic diarrhea virus and cholera toxin B subunit fusion protein transiently expressed in infiltrated Nicotiana benthamiana leaves

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A protocol for the gentle purification of virus-like particles produced in plants

(2015) Hadrien Peyret   JOURNAL OF VIROLOGICAL METHODS

The Use of Transient Expression Systems for the Rapid Production of Virus-like Particles in Plants

(2013) Eva Thuenemann et al.   CURRENT PHARMACEUTICAL DESIGN

A method for rapid production of heteromultimeric protein complexes in plants: assembly of protective bluetongue virus-like particles

(2013) Eva C. Thuenemann et al.   PLANT BIOTECHNOLOGY JOURNAL

Effect of mucosal and systemic immunization with virus-like particles of severe acute respiratory syndrome coronavirus in mice

(2010) Baojing Lu et al.   IMMUNOLOGY

A structural analysis of M protein in coronavirus assembly and morphology

(2010) Benjamin W. Neuman et al.   JOURNAL OF STRUCTURAL BIOLOGY

Proteolytic Activation of the Spike Protein at a Novel RRRR/S Motif Is Implicated in Furin-Dependent Entry, Syncytium Formation, and Infectivity of Coronavirus Infectious Bronchitis Virus in Cultured Cells

(2009) Y. Yamada et al.   JOURNAL OF VIROLOGY

The M, E, and N Structural Proteins of the Severe Acute Respiratory Syndrome Coronavirus Are Required for Efficient Assembly, Trafficking, and Release of Virus-Like Particles

(2008) Y. L. Siu et al.   JOURNAL OF VIROLOGY

Virus-Like Particles of SARS-Like Coronavirus Formed by Membrane Proteins from Different Origins Demonstrate Stimulating Activity in Human Dendritic Cells

(2008) Bingke Bai et al.   PLoS One

Chimeric coronavirus-like particles carrying severe acute respiratory syndrome coronavirus (SCoV) S protein protect mice against challenge with SCoV

(2008) Kumari G. Lokugamage et al.   VACCINE